{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:16:42Z","timestamp":1791919002995,"version":"4.3.4"},"reference-count":49,"publisher":"Informa UK Limited","issue":"12","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Nanomedicine"],"published-print":{"date-parts":[[2024,5,14]]},"DOI":"10.2217\/nnm-2024-0023","type":"journal-article","created":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T13:22:33Z","timestamp":1713532953000},"page":"1051-1068","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":9,"title":["Enhanced oral bioavailability of levormeloxifene and raloxifene by nanoemulsion: simultaneous bioanalysis using liquid chromatography-tandem mass spectrometry"],"prefix":"10.1080","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8883-1719","authenticated-orcid":false,"given":"Divya","family":"Chauhan","sequence":"first","affiliation":[{"name":"Division of Pharmaceutics & Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, 226031, Uttar Pradesh, India"},{"name":"Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debalina","family":"Maity","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutics & Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, 226031, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4092-2320","authenticated-orcid":false,"given":"Pavan K","family":"Yadav","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutics & Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, 226031, Uttar Pradesh, India"},{"name":"Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachin","family":"Vishwakarma","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutics & Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, 226031, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutics & Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, 226031, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8318-9325","authenticated-orcid":false,"given":"Manish K","family":"Chourasia","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutics & Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, 226031, Uttar Pradesh, India"},{"name":"Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7703-9307","authenticated-orcid":false,"given":"Jiaur R","family":"Gayen","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutics & Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, 226031, Uttar Pradesh, India"},{"name":"Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,4,19]]},"reference":[{"key":"e_1_3_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jmwh.12954"},{"key":"e_1_3_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpendmet0325"},{"key":"e_1_3_7_5_1","doi-asserted-by":"publisher","DOI":"10.3803\/EnM.2021.301"},{"key":"e_1_3_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2006.02.007"},{"key":"e_1_3_7_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.123938"},{"key":"e_1_3_7_8_1","doi-asserted-by":"publisher","DOI":"10.4155\/bio-2023-0046"},{"key":"e_1_3_7_9_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S6083"},{"key":"e_1_3_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.07.470"},{"issue":"4","key":"e_1_3_7_11_1","first-page":"789","article-title":"Pharmacokinetic interaction potential assessment of cladrin, a potent bioactive constituent of Butea monosperma, and raloxifene, a prescription anti-osteoporotic by in vitro ADME approach","volume":"21","author":"Chauhan D","year":"2022","unstructured":"Chauhan D, Sultana N, Yadav PK et al. Pharmacokinetic interaction potential assessment of cladrin, a potent bioactive constituent of Butea monosperma, and raloxifene, a prescription anti-osteoporotic by in vitro ADME approach. Indian J. Tradit. Knowl. 21(4), 789\u2013796 (2022).","journal-title":"Indian J. Tradit. Knowl."},{"key":"e_1_3_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001831"},{"key":"e_1_3_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(01)00465-3"},{"key":"e_1_3_7_14_1","doi-asserted-by":"publisher","DOI":"10.4155\/bio-2023-0206"},{"key":"e_1_3_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12275-021-0617-7"},{"key":"e_1_3_7_16_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200528080-00006"},{"key":"e_1_3_7_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm401144z"},{"key":"e_1_3_7_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0306-5251.2001.01181.x"},{"key":"e_1_3_7_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2019.1568403"},{"key":"e_1_3_7_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21207586"},{"key":"e_1_3_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcma.2013.03.010"},{"key":"e_1_3_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-018-4414-z"},{"key":"e_1_3_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-020-05497-8"},{"issue":"5","key":"e_1_3_7_24_1","first-page":"503","article-title":"Metabolism, disposition, excretion, and pharmacokinetics of levormeloxifene, a selective estrogen receptor modulator, in the rat","volume":"28","author":"Mountfield RJ","year":"2000","unstructured":"Mountfield RJ, Kiehr B, John BA. Metabolism, disposition, excretion, and pharmacokinetics of levormeloxifene, a selective estrogen receptor modulator, in the rat. Drug Metab. Dispos. 28(5), 503\u2013513 (2000).","journal-title":"Drug Metab. Dispos."},{"key":"e_1_3_7_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199712043372301"},{"issue":"0607","key":"e_1_3_7_26_1","first-page":"847","article-title":"Raloxifene and cardiovascular events in osteoporotic postmenopausal women","volume":"287","author":"Barrett-Connor E","year":"2015","unstructured":"Barrett-Connor E, Grady D, Sashegyi A, Anderson PW, Cox DA, Harper KD. Raloxifene and cardiovascular events in osteoporotic postmenopausal women. JAMA 287(0607), 847\u2013857 (2015).","journal-title":"JAMA"},{"key":"e_1_3_7_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.17.10.2264"},{"issue":"2","key":"e_1_3_7_28_1","first-page":"755","article-title":"Efficacy of levormeloxifene in the prevention of postmenopausal bone loss and on the lipid profile compared to low dose hormone replacement therapy","volume":"86","author":"Alexandersen P","year":"2015","unstructured":"Alexandersen P, Riis BJ, Stakkestad JA, Delmas PD. Efficacy of levormeloxifene in the prevention of postmenopausal bone loss and on the lipid profile compared to low dose hormone replacement therapy. J. Clin. Endocrinol. Metab. 86(2), 755\u2013760 (2015).","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"e_1_3_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2007.05.004"},{"key":"e_1_3_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.202000835"},{"key":"e_1_3_7_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano10061085"},{"key":"e_1_3_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2016.03.052"},{"key":"e_1_3_7_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42250-022-00457-7"},{"key":"e_1_3_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjac.2022.100197"},{"key":"e_1_3_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2016.07.042"},{"key":"e_1_3_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2009.01.003"},{"key":"e_1_3_7_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac020361s"},{"key":"e_1_3_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2017.09.042"},{"key":"e_1_3_7_39_1","doi-asserted-by":"publisher","DOI":"10.3109\/02652048.2014.950710"},{"key":"e_1_3_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.10.010"},{"key":"e_1_3_7_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13197-017-2800-8"},{"key":"e_1_3_7_42_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph15010070"},{"key":"e_1_3_7_43_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S80297"},{"key":"e_1_3_7_44_1","doi-asserted-by":"publisher","DOI":"10.4155\/bio-2022-0100"},{"key":"e_1_3_7_45_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S33186"},{"key":"e_1_3_7_46_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-020-01855-1"},{"key":"e_1_3_7_47_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S124158"},{"key":"e_1_3_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2023.123209"},{"key":"e_1_3_7_49_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2022-0268"},{"key":"e_1_3_7_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules15118478"},{"key":"e_1_3_7_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2010.03.029"}],"container-title":["Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/nnm-2024-0023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T19:05:26Z","timestamp":1727204726000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/nnm-2024-0023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,19]]},"references-count":49,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,5,14]]}},"alternative-id":["10.2217\/nnm-2024-0023"],"URL":"https:\/\/doi.org\/10.2217\/nnm-2024-0023","relation":{},"ISSN":["1743-5889","1748-6963"],"issn-type":[{"value":"1743-5889","type":"print"},{"value":"1748-6963","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,19]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=innm20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=innm20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}