{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T01:25:12Z","timestamp":1794014712330,"version":"4.8.0"},"reference-count":49,"publisher":"Informa UK Limited","issue":"13","funder":[{"name":"Internal Grant Agency, Ministry of Health","award":["NT-14025-3\/2013"],"award-info":[{"award-number":["NT-14025-3\/2013"]}]},{"name":"(IKEM, Prague, Czech Republic)","award":["00023001"],"award-info":[{"award-number":["00023001"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Pharmacogenomics"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.2217\/pgs-2016-0071","type":"journal-article","created":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T11:29:33Z","timestamp":1465903773000},"page":"1405-1414","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":19,"title":["Rare Variants in known and Novel Candidate Genes Predisposing to Statin-Associated Myopathy"],"prefix":"10.1080","volume":"17","author":[{"given":"Magdal\u00e9na","family":"Ne\u0159oldov\u00e1","sequence":"first","affiliation":[{"name":"Laboratory of Experimental Hepatology, Center for Experimental Medicine, Institute for Clinical & Experimental Medicine, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktor","family":"Str\u00e1neck\u00fd","sequence":"additional","affiliation":[{"name":"Institute of Inherited Metabolic Diseases, First Medical Faculty, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate\u0159ina","family":"Hoda\u0148ov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Inherited Metabolic Diseases, First Medical Faculty, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Hartmannov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Inherited Metabolic Diseases, First Medical Faculty, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Piherov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Inherited Metabolic Diseases, First Medical Faculty, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"P\u0159istoupilov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Inherited Metabolic Diseases, First Medical Faculty, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Mr\u00e1zov\u00e1","sequence":"additional","affiliation":[{"name":"Laboratory for Atherosclerosis Research, Center for Experimental Medicine, Institute for Clinical & Experimental Medicine, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Vrabl\u00edk","sequence":"additional","affiliation":[{"name":"Third Medical Department, First Faculty of Medicine, Charles University & General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u011bra","family":"Ad\u00e1mkov\u00e1","sequence":"additional","affiliation":[{"name":"Preventive Cardiology Department, Institute for Clinical & Experimental Medicine, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaroslav A","family":"Hub\u00e1\u010dek","sequence":"additional","affiliation":[{"name":"Laboratory for Atherosclerosis Research, Center for Experimental Medicine, Institute for Clinical & Experimental Medicine, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Jirsa","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental Hepatology, Center for Experimental Medicine, Institute for Clinical & Experimental Medicine, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislav","family":"Kmoch","sequence":"additional","affiliation":[{"name":"Institute of Inherited Metabolic Diseases, First Medical Faculty, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,6,14]]},"reference":[{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e32833f0fc7"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.13.1681"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200022060-00003"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12604"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-014-1776-9"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2009.11.033"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12360"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOL.0000000000000125"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0801936"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000034125.94759.41"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2010.255"},{"key":"e_1_3_4_14_1","unstructured":"1000 Genomes . A deep catalog of human genetic variation . http:\/\/browser.1000genomes.org\/index.html ."},{"key":"e_1_3_4_15_1","unstructured":"NHLBI Exome Sequencing Project (ESP) . Exome variant server . http:\/\/evs.gs.washington.edu\/EVS\/ ."},{"key":"e_1_3_4_16_1","unstructured":"ExAC Browser (Beta) | Exome Aggregation Consortium . http:\/\/exac.broadinstitute.org\/ ."},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2010.04.007"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6614"},{"key":"e_1_3_4_19_1","unstructured":"Picard . http:\/\/broadinstitute.github.io\/picard\/ ."},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.4161\/fly.19695"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003153"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts146"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2012-1012"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(00)00150-4"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2012.06.012"},{"key":"e_1_3_4_26_1","volume-title":"GeneReviews(R)","author":"Malicdan MCV","year":"1993","unstructured":"Malicdan MCV , NishinoI . Central core disease . In : GeneReviews(R) . PagonRA , AdamMP , ArdingerHHet al. ( Eds ). University of Washington , WA, USA ( 1993 )."},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110888"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2010.212"},{"key":"e_1_3_4_29_1","volume-title":"GeneReviews(R)","author":"Bonne G","year":"1993","unstructured":"Bonne G , LeturcqF , Ben YaouR . Emery-Dreifuss muscular dystrophy . In : GeneReviews(R) . PagonRA , AdamMP , ArdingerHHet al. ( Eds ). University of Washington , WA, USA ( 1993 )."},{"key":"e_1_3_4_30_1","volume-title":"GeneReviews (Internet)","author":"Pegoraro E","year":"2012","unstructured":"Pegoraro E , HoffmanEP . Limb-girdle muscular dystrophy overview . In : GeneReviews (Internet) . PagonRA , AdamMP , ArdingerHH ( Eds ). University of Washington Seattle , WA, USA ( 2012 )."},{"key":"e_1_3_4_31_1","volume-title":"GeneReviews (Internet)","author":"North KN","year":"2015","unstructured":"North KN , RyanMN . Nemaline myopathy . In : GeneReviews (Internet) . PagonRA , AdamMP , ArdingerHH ( Eds ). University of Washington Seattle , WA, USA ( 2015 )."},{"key":"e_1_3_4_32_1","volume-title":"GeneReviews (Internet)","author":"Abicht A","year":"2012","unstructured":"Abicht A , MullerJS , LochmullerH . Congenital myasthenic syndromes . In : GeneReviews (Internet) . PagonRA , AdamMP , ArdingerHH ( Eds ). University of Washington Seattle , WA, USA ( 2012 )."},{"key":"e_1_3_4_33_1","volume-title":"GeneReviews(R)","author":"Chinnery PF","year":"1993","unstructured":"Chinnery PF . Mitochondrial disorders overview . In : GeneReviews(R) . PagonRA , AdamMP , ArdingerHHet al.University of Washington Seattle , WA, USA ( 1993 )."},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1558973"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1086\/519795"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1001322"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2303"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003874"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2003-4-5-p3"},{"key":"e_1_3_4_40_1","unstructured":"GeneRIF: Gene Reference into Function . www.ncbi.nlm.nih.gov\/gene\/about-generif ."},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.33549\/physiolres.932865"},{"issue":"2","key":"e_1_3_4_42_1","first-page":"22","article-title":"Possible gene\u2013gender interaction between the SLCO1B1 polymorphism and statin treatment efficacy","volume":"33","author":"Hubacek JA","year":"2012","unstructured":"Hubacek JA , DlouhaD , AdamkovaV , LanskaV , CeskaR , VrablikM . Possible gene\u2013gender interaction between the SLCO1B1 polymorphism and statin treatment efficacy . Neuro Endocrinol. Lett.33 ( Suppl. 2 ), 22 \u2013 25 ( 2012 ).","journal-title":"Neuro Endocrinol. Lett."},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.110.002857"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0908094"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI59526"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.109.203596"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.10.118"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2014.02.023"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.12482"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2008.00079.x"},{"issue":"12","key":"e_1_3_4_51_1","first-page":"3940","article-title":"The muscle-specific ubiquitin ligase atrogin-1\/MAFbx mediates statin-induced muscle toxicity","volume":"117","author":"Hanai J","year":"2007","unstructured":"Hanai J , CaoP , TanksalePet al. The muscle-specific ubiquitin ligase atrogin-1\/MAFbx mediates statin-induced muscle toxicity . J. Clin. Invest.117 ( 12 ), 3940 \u2013 3951 ( 2007 ).","journal-title":"J. Clin. Invest."}],"container-title":["Pharmacogenomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/pgs-2016-0071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T19:21:30Z","timestamp":1715973690000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/pgs-2016-0071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,14]]},"references-count":49,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.2217\/pgs-2016-0071"],"URL":"https:\/\/doi.org\/10.2217\/pgs-2016-0071","relation":{},"ISSN":["1462-2416","1744-8042"],"issn-type":[{"value":"1462-2416","type":"print"},{"value":"1744-8042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,14]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ipgs20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ipgs20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-04-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-05-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-06-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}