{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T05:17:06Z","timestamp":1774415826047,"version":"3.50.1"},"reference-count":61,"publisher":"Informa UK Limited","issue":"5","funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","award":["WO 2385\/1-1"],"award-info":[{"award-number":["WO 2385\/1-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Clinician Scientist program of the University of Tubingen","award":["418-0-0"],"award-info":[{"award-number":["418-0-0"]}]},{"name":"FP6 Integrated Project EPICURE","award":["LSHM-CT-2006-037315"],"award-info":[{"award-number":["LSHM-CT-2006-037315"]}]},{"name":"DFG EUROCORES Program EuroEPINOMICS","award":["SA434\/5\u2013xs1"],"award-info":[{"award-number":["SA434\/5\u2013xs1"]}]},{"name":"DFG Research Unit","award":["FOR2715 (SA434\/6-1)"],"award-info":[{"award-number":["FOR2715 (SA434\/6-1)"]}]},{"name":"BOF-University of Antwerp","award":["FFB180053"],"award-info":[{"award-number":["FFB180053"]}]},{"name":"Frontier Works Organization","award":["1861419N"],"award-info":[{"award-number":["1861419N"]}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"crossref","award":["279062"],"award-info":[{"award-number":["279062"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Pharmacogenomics"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.2217\/pgs-2019-0179","type":"journal-article","created":{"date-parts":[[2020,4,20]],"date-time":"2020-04-20T09:41:39Z","timestamp":1587375699000},"page":"325-335","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":26,"title":["Pharmacoresponse in Genetic Generalized Epilepsy: A Genome-Wide Association Study"],"prefix":"10.1080","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1460-6623","authenticated-orcid":false,"given":"Stefan","family":"Wolking","sequence":"first","affiliation":[{"name":"Department of Neurology &amp;\u00a0Epileptology, Hertie Institute for Clinical Brain Research, University of T\u00fcbingen, 72076T\u00fcbingen, Germany"},{"name":"Department of Neurosciences, CHUM Research Center, University of Montreal, Montreal, H2X 0A9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert","family":"Schulz","sequence":"additional","affiliation":[{"name":"Cologne Center for Genomics, University of Cologne, 50931Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne T","family":"Nies","sequence":"additional","affiliation":[{"name":"Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, 70376Stuttgart, Germany"},{"name":"University of T\u00fcbingen, 72076T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"McCormack","sequence":"additional","affiliation":[{"name":"Molecular &amp; Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elke","family":"Schaeffeler","sequence":"additional","affiliation":[{"name":"Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, 70376Stuttgart, Germany"},{"name":"University of T\u00fcbingen, 72076T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pauls","family":"Auce","sequence":"additional","affiliation":[{"name":"Walton Centre NHS Foundation Trust, Liverpool, L33 4YD, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreja","family":"Avbersek","sequence":"additional","affiliation":[{"name":"Department of Clinical &amp; Experimental Epilepsy, UCL Queen Square Institute of Neurology, London &amp; Chalfont Centre for Epilepsy, London, SL9 0RJ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicitas","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of Neurology &amp;\u00a0Epileptology, Hertie Institute for Clinical Brain Research, University of T\u00fcbingen, 72076T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl M","family":"Klein","sequence":"additional","affiliation":[{"name":"Epilepsy Center Frankfurt Rhine-Main, University Hospital Frankfurt, Goethe University Frankfurt, 60590Frankfurt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Krenn","sequence":"additional","affiliation":[{"name":"Department of Neurology, Medical University of Vienna, 1090Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rikke S","family":"M\u00f8ller","sequence":"additional","affiliation":[{"name":"Danish Epilepsy Centre \u2013\u00a0Filadelfia, 4293Dianalund, Denmark"},{"name":"Department of Regional Health Research, University of Southern Denmark, 5000Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Nikanorova","sequence":"additional","affiliation":[{"name":"Danish Epilepsy Centre \u2013\u00a0Filadelfia, 4293Dianalund, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Weckhuysen","sequence":"additional","affiliation":[{"name":"Neurogenetics Group, Center for Molecular Neurology, VIB-University of Antwerp, 2650Edegem, Belgium"},{"name":"Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, 2650Edegem, Belgium"},{"name":"Department of Neurology, Antwerp University Hospital, 2650Edegem, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"EpiPGx","family":"Consortium","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianpiero L","family":"Cavalleri","sequence":"additional","affiliation":[{"name":"Molecular &amp; Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland"},{"name":"Division of Brain Sciences, Imperial College Faculty of Medicine, London, SW2 2AZ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norman","family":"Delanty","sequence":"additional","affiliation":[{"name":"Molecular &amp; Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland"},{"name":"Division of Neurology, Beaumont Hospital, Dublin 9, Ireland"},{"name":"The FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chantal","family":"Depondt","sequence":"additional","affiliation":[{"name":"Department of Neurology, H\u00f4pital Erasme, Universit\u00e9 Libre de Bruxelles, 1070Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R","family":"Johnson","sequence":"additional","affiliation":[{"name":"Division of Brain Sciences, Imperial College Faculty of Medicine, London, SW2 2AZ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bobby PC","family":"Koeleman","sequence":"additional","affiliation":[{"name":"Department of Genetics, University Medical Center Utrecht, 3584Utrecht, The\u00a0Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfram S","family":"Kunz","sequence":"additional","affiliation":[{"name":"Institute of Experimental Epileptology &amp; Cognition Research &amp; Department of Epileptology, University of Bonn, 53127Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony G","family":"Marson","sequence":"additional","affiliation":[{"name":"Department of Molecular &amp; Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, L69 7ZB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josemir W","family":"Sander","sequence":"additional","affiliation":[{"name":"Department of Clinical &amp; Experimental Epilepsy, UCL Queen Square Institute of Neurology, London &amp; Chalfont Centre for Epilepsy, London, SL9 0RJ, UK"},{"name":"Stichting Epilepsie Instellingen Nederland (SEIN), 2103Heemstede, The\u00a0Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graeme J","family":"Sills","sequence":"additional","affiliation":[{"name":"Department of Molecular &amp; Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, L69 7ZB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasquale","family":"Striano","sequence":"additional","affiliation":[{"name":"Pediatric Neurology &amp; Muscular Diseases Unit, IRCCS \u2018G. Gaslini\u2019 Institute, 16147Genova, Italy"},{"name":"Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal &amp; Child Health, University of Genova, 16147Genova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Zara","sequence":"additional","affiliation":[{"name":"Laboratory of Neurogenetics and Neuroscience, IRCCS \u2018G. Gaslini\u2019 Institute, 16147Genova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fritz","family":"Zimprich","sequence":"additional","affiliation":[{"name":"Department of Neurology, Medical University of Vienna, 1090Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yvonne G","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Neurology &amp;\u00a0Epileptology, Hertie Institute for Clinical Brain Research, University of T\u00fcbingen, 72076T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9938-7126","authenticated-orcid":false,"given":"Roland","family":"Krause","sequence":"additional","affiliation":[{"name":"Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4362Esch-sur-Alzette, Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Sisodiya","sequence":"additional","affiliation":[{"name":"Department of Clinical &amp; Experimental Epilepsy, UCL Queen Square Institute of Neurology, London &amp; Chalfont Centre for Epilepsy, London, SL9 0RJ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Schwab","sequence":"additional","affiliation":[{"name":"Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, 70376Stuttgart, Germany"},{"name":"Department of Clinical Pharmacology, University Hospital T\u00fcbingen, 72076T\u00fcbingen, Germany"},{"name":"Department of Pharmacy &amp; Biochemistry, University T\u00fcbingen, 72076T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Sander","sequence":"additional","affiliation":[{"name":"Cologne Center for Genomics, University of Cologne, 50931Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Lerche","sequence":"additional","affiliation":[{"name":"Department of Neurology &amp;\u00a0Epileptology, Hertie Institute for Clinical Brain Research, University of T\u00fcbingen, 72076T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,4,20]]},"reference":[{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07524-z"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0501-49"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng885"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21724"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.292"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp311"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp262"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1005226"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182a95829"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2019.05.020"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30215-1"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(16)30359-3"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2009.02397.x"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182563b19"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2017.3949"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12074"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/428486a"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12217"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1013297"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000004853"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001034"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24886"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2017.01.014"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/17425255.2018.1473377"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-015-0267-1"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.2133\/dmpk.DMPK-11-NT-144"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-015-1925-9"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dmpk.2015.05.002"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6509-3"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.13210"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01866.x"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.13709"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1086\/519795"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1847"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000529"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1681"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1004219"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2156-9-36"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01261-5"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2017.1328499"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12182"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01516.x"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1080\/13543784.2018.1543398"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2016.04.006"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.115.5.1319"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13908"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1904348116"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1851-06.2006"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2008.06.001"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2012.12.003"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00648"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0095579"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.668392"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200305018"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052773"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.08.040"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2009.01.017"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2014.07.004"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1007285"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08185"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3863"}],"container-title":["Pharmacogenomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/pgs-2019-0179","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T21:40:33Z","timestamp":1715982033000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/pgs-2019-0179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":61,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.2217\/pgs-2019-0179"],"URL":"https:\/\/doi.org\/10.2217\/pgs-2019-0179","relation":{},"ISSN":["1462-2416","1744-8042"],"issn-type":[{"value":"1462-2416","type":"print"},{"value":"1744-8042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ipgs20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ipgs20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}