{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T03:00:13Z","timestamp":1768014013660,"version":"3.49.0"},"reference-count":82,"publisher":"Informa UK Limited","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacogenomics"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.2217\/pgs.10.62","type":"journal-article","created":{"date-parts":[[2010,7,6]],"date-time":"2010-07-06T10:04:32Z","timestamp":1278410672000},"page":"927-941","source":"Crossref","is-referenced-by-count":38,"title":["Genetic Profile of Patients with Epilepsy on First-Line Antiepileptic Drugs and Potential Directions for Personalized Treatment"],"prefix":"10.1080","volume":"11","author":[{"given":"Sandeep","family":"Grover","sequence":"first","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mandaville","family":"Gourie-Devi","sequence":"additional","affiliation":[{"name":"Institute of Human Behavior &amp; Allied Sciences (IHBAS), Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruchi","family":"Baghel","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sangeeta","family":"Sharma","sequence":"additional","affiliation":[{"name":"Institute of Human Behavior &amp; Allied Sciences (IHBAS), Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran","family":"Bala","sequence":"additional","affiliation":[{"name":"Institute of Human Behavior &amp; Allied Sciences (IHBAS), Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meena","family":"Gupta","sequence":"additional","affiliation":[{"name":"Institute of Human Behavior &amp; Allied Sciences (IHBAS), Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishnamoorthy","family":"Narayanasamy","sequence":"additional","affiliation":[{"name":"The Centre for Genomic Application (TCGA), New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binuja","family":"Varma","sequence":"additional","affiliation":[{"name":"The Centre for Genomic Application (TCGA), New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meenal","family":"Gupta","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavita","family":"Kaur","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Puneet","family":"Talwar","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harpreet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudheer","family":"Giddaluru","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhay","family":"Sharma","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir K","family":"Brahmachari","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Indian Genome Variation","family":"Consortium","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ritushree","family":"Kukreti","sequence":"additional","affiliation":[{"name":"Institute of Genomics &amp; Integrative Biology (IGIB), Council of Scientific &amp; Industrial Research (CSIR), India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2010,7,6]]},"reference":[{"key":"e_1_3_4_3_1_1","doi-asserted-by":"publisher","DOI":"10.1159\/000080090"},{"key":"e_1_3_4_3_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2009.53"},{"key":"e_1_3_4_3_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1997.tb01251.x"},{"key":"e_1_3_4_3_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6505(1998)6:3<100::AID-EVAN4>3.0.CO;2-I"},{"key":"e_1_3_4_3_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-005-0009-9"},{"key":"e_1_3_4_3_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12041-008-0002-x"},{"key":"e_1_3_4_3_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.2003.01883.x"},{"key":"e_1_3_4_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2008.08.019"},{"key":"e_1_3_4_3_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/16.3.1215"},{"key":"e_1_3_4_3_10_1","doi-asserted-by":"publisher","DOI":"10.1086\/302959"},{"key":"e_1_3_4_3_11_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.30.11.1170"},{"key":"e_1_3_4_3_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.1999.00898.x"},{"key":"e_1_3_4_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(94)90071-X"},{"key":"e_1_3_4_3_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008571-200110000-00006"},{"key":"e_1_3_4_3_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e328329940b"},{"key":"e_1_3_4_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(91)91680-B"},{"key":"e_1_3_4_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70352-0"},{"key":"e_1_3_4_3_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008571-200106000-00002"},{"key":"e_1_3_4_3_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e318030def0"},{"key":"e_1_3_4_3_20_1","doi-asserted-by":"publisher","DOI":"10.5483\/BMBRep.2007.40.3.448"},{"key":"e_1_3_4_3_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.fpc.0000230114.41828.73"},{"key":"e_1_3_4_3_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1998.tb01330.x"},{"key":"e_1_3_4_3_23_1","doi-asserted-by":"publisher","DOI":"10.2133\/dmpk.20.107"},{"key":"e_1_3_4_3_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2003.07.018"},{"key":"e_1_3_4_3_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.fpc.0000174787.92861.91"},{"key":"e_1_3_4_3_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2006.00761.x"},{"key":"e_1_3_4_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2006.05.015"},{"key":"e_1_3_4_3_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(99)00034-9"},{"key":"e_1_3_4_3_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2710.2006.00712.x"},{"key":"e_1_3_4_3_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9236(97)90031-X"},{"key":"e_1_3_4_3_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002280050703"},{"key":"e_1_3_4_3_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2004.02.010"},{"key":"e_1_3_4_3_33_1","doi-asserted-by":"publisher","DOI":"10.2217\/14622416.9.5.527"},{"key":"e_1_3_4_3_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/00498250110055479"},{"key":"e_1_3_4_3_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/em.10199"},{"key":"e_1_3_4_3_36_1","doi-asserted-by":"publisher","DOI":"10.2133\/dmpk.17.150"},{"key":"e_1_3_4_3_37_1","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0090-9556(25)06571-7","volume":"9","author":"Tybring G","year":"1981","unstructured":"Tybring G , von Bahr C, Bertilsson L, Collste H, Glaumann H, Solbrand M: Metabolism of carbamazepine and its epoxide metabolite in human and rat liver in vitro. Drug Metab. Dispos.9 , 561\u2013564 (1981).","journal-title":"Drug Metab. Dispos."},{"key":"e_1_3_4_3_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/3.3.421"},{"key":"e_1_3_4_3_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/0049825021000061615"},{"key":"e_1_3_4_3_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-004-0878-1"},{"key":"e_1_3_4_3_41_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.30.11.1250"},{"key":"e_1_3_4_3_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4439(98)00013-1"},{"key":"e_1_3_4_3_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clpt.2004.01.010"},{"key":"e_1_3_4_3_44_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.104.073114"},{"key":"e_1_3_4_3_45_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.108.022426"},{"key":"e_1_3_4_3_46_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.11.023"},{"key":"e_1_3_4_3_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9236(03)00053-5"},{"key":"e_1_3_4_3_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2008.08.032"},{"key":"e_1_3_4_3_49_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.103.054197"},{"key":"e_1_3_4_3_50_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200111160-00037"},{"key":"e_1_3_4_3_51_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.7.3473"},{"key":"e_1_3_4_3_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.tpj.6500025"},{"key":"e_1_3_4_3_53_1","doi-asserted-by":"publisher","DOI":"10.1517\/14622416.6.4.411"},{"key":"e_1_3_4_3_54_1","doi-asserted-by":"publisher","DOI":"10.2217\/pgs.09.32"},{"key":"e_1_3_4_3_55_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000141021.42763.F6"},{"key":"e_1_3_4_3_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2009.02059.x"},{"key":"e_1_3_4_3_57_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021986"},{"key":"e_1_3_4_3_58_1","doi-asserted-by":"publisher","DOI":"10.1159\/000109264"},{"key":"e_1_3_4_3_59_1","first-page":"11","article-title":"Association of a polymorphism in MDR1 C3435T with response to antiepileptic drug treatment in ethic Han Chinese children with epilepsy.","volume":"9","author":"Chen L","year":"2007","unstructured":"Chen L , LiuCQ, HuY, XiaoZT, ChenY, LiaoJX: Association of a polymorphism in MDR1 C3435T with response to antiepileptic drug treatment in ethic Han Chinese children with epilepsy.Zhongguo Dang Dai Er Ke Za Zhi9 , 11\u201314 (2007).","journal-title":"Zhongguo Dang Dai Er Ke Za Zhi"},{"key":"e_1_3_4_3_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2007.04.013"},{"key":"e_1_3_4_3_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2005.46304.x"},{"key":"e_1_3_4_3_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2006.02.015"},{"key":"e_1_3_4_3_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2008.03.004"},{"key":"e_1_3_4_3_64_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000137051.33486.C7"},{"key":"e_1_3_4_3_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01661.x"},{"key":"e_1_3_4_3_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2008.01.003"},{"key":"e_1_3_4_3_67_1","doi-asserted-by":"publisher","DOI":"10.2217\/14622416.7.4.551"},{"key":"e_1_3_4_3_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2008.12.001"},{"key":"e_1_3_4_3_69_1","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e318067ce90"},{"key":"e_1_3_4_3_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2006.10.004"},{"key":"e_1_3_4_3_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1989.tb05300.x"},{"key":"e_1_3_4_3_72_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0407346102"},{"key":"e_1_3_4_3_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2008.03203.x"},{"key":"e_1_3_4_3_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01549_4.x"},{"key":"e_1_3_4_3_75_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000344401.02915.00"},{"key":"e_1_3_4_3_76_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e3283117d67"},{"key":"e_1_3_4_3_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/1252"},{"key":"e_1_3_4_3_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2005.03.003"},{"key":"e_1_3_4_3_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10038-008-0306-y"},{"key":"e_1_3_4_3_80_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11373-005-9009-y"},{"key":"e_1_3_4_3_81_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.111065098"},{"key":"e_1_3_4_3_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01049.x"}],"container-title":["Pharmacogenomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/pgs.10.62","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T17:08:37Z","timestamp":1740244117000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/pgs.10.62"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":82,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.2217\/pgs.10.62"],"URL":"https:\/\/doi.org\/10.2217\/pgs.10.62","relation":{},"ISSN":["1462-2416","1744-8042"],"issn-type":[{"value":"1462-2416","type":"print"},{"value":"1744-8042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7]]}}}