{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:43:15Z","timestamp":1790239395846,"version":"4.1.0"},"reference-count":35,"publisher":"Informa UK Limited","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacogenomics"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.2217\/pgs.13.124","type":"journal-article","created":{"date-parts":[[2013,9,11]],"date-time":"2013-09-11T15:26:16Z","timestamp":1378913176000},"page":"1389-1396","source":"Crossref","is-referenced-by-count":9,"title":["Irreversible Hepatotoxicity After Administration of Trabectedin to a Pleiomorphic Sarcoma Patient with a Rare\n            <i>ABCC2<\/i>\n            Polymorphism: A Case Report"],"prefix":"10.1080","volume":"14","author":[{"given":"Anne-Pascale","family":"Laurenty","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, Institut Claudius Regaud, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabienne","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Pharmacology &amp; EA4553, Institut Claudius Regaud, 20\u201324, rue du Pont St Pierre, 31052Toulouse Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Chatelut","sequence":"additional","affiliation":[{"name":"Department of Pharmacology &amp; EA4553, Institut Claudius Regaud, 20\u201324, rue du Pont St Pierre, 31052Toulouse Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"B\u00e9trian","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Institut Claudius Regaud, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal Le","family":"Guellec","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, H\u00f4pital Bretonneau, CHRU Tours, Tours, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Hennebelle","sequence":"additional","affiliation":[{"name":"Department of Pharmacology &amp; EA4553, Institut Claudius Regaud, 20\u201324, rue du Pont St Pierre, 31052Toulouse Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie Le","family":"Guellec","sequence":"additional","affiliation":[{"name":"Department of Anatomopathology, Institut Claudius Regaud, Toulouse Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Chevreau","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Institut Claudius Regaud, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2013,9,11]]},"reference":[{"key":"e_1_3_3_3_1_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi960306b"},{"key":"e_1_3_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2009.03490.x"},{"key":"e_1_3_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2013.01.008"},{"key":"e_1_3_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-011-9662-0"},{"key":"e_1_3_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-012-1864-4"},{"key":"e_1_3_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-2127"},{"key":"e_1_3_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0091270003253617"},{"key":"e_1_3_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(05)70097-0"},{"key":"e_1_3_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(03)00458-1"},{"key":"e_1_3_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2006.24.18_suppl.9568"},{"key":"e_1_3_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2009.02.020"},{"key":"e_1_3_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-005-4538-9"},{"issue":"15","key":"e_1_3_3_3_13_1","first-page":"4256","article-title":"Hepatobiliary damage and changes in hepatic gene expression caused by the antitumor drug ecteinascidin-743 (ET-743) in the female rat.","volume":"62","author":"Donald S","year":"2002","unstructured":"Donald S , VerschoyleRD, EdwardsR et al. Hepatobiliary damage and changes in hepatic gene expression caused by the antitumor drug ecteinascidin-743 (ET-743) in the female rat. Cancer Res. 62(15) , 4256\u20134262 (2002).","journal-title":"Cancer Res."},{"key":"e_1_3_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-009-0748-0"},{"key":"e_1_3_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008571-200107000-00008"},{"key":"e_1_3_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.2133\/dmpk.DMPK-11-RV-111"},{"key":"e_1_3_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-006-7773-9"},{"key":"e_1_3_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-009-9234-8"},{"key":"e_1_3_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1067\/mcp.2001.114164"},{"key":"e_1_3_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.7.3473"},{"key":"e_1_3_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.tpj.6500403"},{"key":"e_1_3_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clpt.2006.08.012"},{"key":"e_1_3_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e328329940b"},{"key":"e_1_3_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.2217\/pgs.10.95"},{"key":"e_1_3_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.11.023"},{"key":"e_1_3_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e32834d672b"},{"key":"e_1_3_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2005.01.005"},{"key":"e_1_3_3_3_28_1","first-page":"389","volume":"38","author":"Thummel KE","year":"1998","unstructured":"Thummel KE , WilkinsonGR. In vitro and in vivo drug interactions involving human CYP3A. Annu. Rev. Pharmacol. Toxicol.38 , 389\u2013430 (1998).","journal-title":"In vitro"},{"issue":"12","key":"e_1_3_3_3_29_1","first-page":"4725","article-title":"Pharmacokinetics and pharmacodynamics of the novel marine-derived anticancer agent ecteinascidin 743 in a Phase I dose-finding study.","volume":"6","author":"van Kesteren C","year":"2000","unstructured":"van Kesteren C , CvitkovicE, TaammaA et al. Pharmacokinetics and pharmacodynamics of the novel marine-derived anticancer agent ecteinascidin 743 in a Phase I dose-finding study. Clin. Cancer Res. 6(12) , 4725\u20134732 (2000).","journal-title":"Clin. Cancer Res."},{"key":"e_1_3_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2009-0325"},{"key":"e_1_3_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-2030-7"},{"key":"e_1_3_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-002-0498-3"},{"key":"e_1_3_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2006.02.010"},{"key":"e_1_3_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018812021549"},{"key":"e_1_3_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.20356"}],"container-title":["Pharmacogenomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/pgs.13.124","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T01:54:33Z","timestamp":1715997273000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/pgs.13.124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["10.2217\/pgs.13.124"],"URL":"https:\/\/doi.org\/10.2217\/pgs.13.124","relation":{},"ISSN":["1462-2416","1744-8042"],"issn-type":[{"value":"1462-2416","type":"print"},{"value":"1744-8042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9]]}}}