{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T10:40:09Z","timestamp":1722681609762},"reference-count":53,"publisher":"Informa UK Limited","issue":"15","funder":[{"name":"European Community\u2019s Seventh Framework Programme","award":["FP7\/2007\u20132013"],"award-info":[{"award-number":["FP7\/2007\u20132013"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacogenomics"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.2217\/pgs.13.182","type":"journal-article","created":{"date-parts":[[2013,11,15]],"date-time":"2013-11-15T16:20:33Z","timestamp":1384532433000},"page":"1907-1914","source":"Crossref","is-referenced-by-count":9,"title":["Opening Pandora\u2018s Box in the UK: a Hypothetical Pharmacogenetic Test for Clozapine"],"prefix":"10.1080","volume":"14","author":[{"given":"Benjamin\ufffdWJ","family":"Spencer","sequence":"first","affiliation":[{"name":"South London &amp; Maudsley NHS Foundation Trust, London, UK"},{"name":"Institute of Psychiatry, King\u2019s College London, London, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Prainsack","sequence":"additional","affiliation":[{"name":"Department of Social Science, Health &amp; Medicine, King\u2019s College London, London, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Rujescu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Halle, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ina","family":"Giegling","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Halle, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David\u00a0A","family":"Collier","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, King\u2019s College London, London, UK."},{"name":"Eli Lilly &amp; Company Ltd, Erl Wood, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona","family":"Gaughran","sequence":"additional","affiliation":[{"name":"South London &amp; Maudsley NHS Foundation Trust, London, UK"},{"name":"Institute of Psychiatry, King\u2019s College London, London, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James H","family":"MacCabe","sequence":"additional","affiliation":[{"name":"South London &amp; Maudsley NHS Foundation Trust, London, UK"},{"name":"Institute of Psychiatry, King\u2019s College London, London, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathy L","family":"Barr","sequence":"additional","affiliation":[{"name":"The Toronto Western Research Institute, Toronto, ON, Canada."},{"name":"The Hospital for Sick Children, Toronto, ON, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Engilbert","family":"Sigurdsson","sequence":"additional","affiliation":[{"name":"University of Iceland, Reykjavik, Iceland."},{"name":"Department of Psychiatry, Landspitali-University Hospital, Reykjavik, Iceland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Stovring","sequence":"additional","affiliation":[{"name":"Department of Public Health, Aarhus University, Denmark."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil\u00a0K","family":"Malhotra","sequence":"additional","affiliation":[{"name":"The Zucker Hillside Hospital, Glen Oaks, NY, USA."},{"name":"Hofstra North Shore-LIJ School of Medicine, Hemptead, NY, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah R","family":"Curran","sequence":"additional","affiliation":[{"name":"South London &amp; Maudsley NHS Foundation Trust, London, UK"},{"name":"Institute of Psychiatry, King\u2019s College London, London, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2013,11,15]]},"reference":[{"key":"e_1_3_2_3_1_1","unstructured":"Melzer E RavenA DetmerDE LingT Zimmern RL; Department of Public Health and Primary Care. My Very Own Medicine: What Must I Know? University of Cambridge Cambridge UK (2003)."},{"key":"e_1_3_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e31818de71c"},{"key":"e_1_3_2_3_3_1","unstructured":"American Psychiatric Association. Diagnostic and Statistical Manual Of Mental Disorders: DSM-IV (4th Edition) . American Psychiatric Association Washington DC USA (1994)."},{"key":"e_1_3_2_3_4_1","unstructured":"WHO. The ICD-10 classification of mental and behavioural disorders: diagnostic criteria for research. WHO Geneva Switzerland (1993)."},{"key":"e_1_3_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-0754"},{"key":"e_1_3_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht024"},{"key":"e_1_3_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2008.08030368"},{"key":"e_1_3_2_3_8_1","unstructured":"Schizophrenia: Core Interventions In The Treatment And Management Of Schizophrenia In Adults In Primary And Secondary Care (Updated Edition). British Psychological Society Royal College of Psychiatrists London UK (2010)."},{"key":"e_1_3_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2012.12060778"},{"key":"e_1_3_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/10401230309085668"},{"key":"e_1_3_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.11r06977"},{"key":"e_1_3_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v64n0107"},{"key":"e_1_3_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.111.105833"},{"key":"e_1_3_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1176\/ps.2008.59.5.567"},{"key":"e_1_3_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psc.2009.12.001"},{"key":"e_1_3_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1432"},{"key":"e_1_3_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2008.10.002"},{"key":"e_1_3_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbn114"},{"key":"e_1_3_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2011.01710.x"},{"key":"e_1_3_2_3_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-012-2922-7"},{"key":"e_1_3_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2013.06.035"},{"key":"e_1_3_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2013.2"},{"key":"e_1_3_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-003-0496-x"},{"key":"e_1_3_2_3_24_1","doi-asserted-by":"publisher","DOI":"10.2147\/ndt.s1752"},{"key":"e_1_3_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.8.869"},{"key":"e_1_3_2_3_26_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199307153290303"},{"key":"e_1_3_2_3_27_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.09m05527yel"},{"key":"e_1_3_2_3_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-011-0185-3"},{"key":"e_1_3_2_3_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2011.146"},{"key":"e_1_3_2_3_30_1","doi-asserted-by":"publisher","DOI":"10.1353\/ken.2002.0001"},{"key":"e_1_3_2_3_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02221-2"},{"key":"e_1_3_2_3_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-012-2773-2"},{"key":"e_1_3_2_3_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2008.02.004"},{"issue":"2","key":"e_1_3_2_3_34_1","first-page":"44","volume":"8","author":"Gigerenzer G","year":"2008","unstructured":"Gigerenzer G , GaissmaierW, Kurz-MilckeE, SchwartzLM, WoloshinS. Helping doctors and patients make sense of health statistics. Psychol. Sci. Public Interest8(2) , 44 (2008).","journal-title":"Psychol. Sci. Public Interest"},{"key":"e_1_3_2_3_35_1","doi-asserted-by":"publisher","DOI":"10.1037\/0003-066X.39.4.341"},{"key":"e_1_3_2_3_36_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2012.14.1\/jmarewski"},{"key":"e_1_3_2_3_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269881110364267"},{"key":"e_1_3_2_3_38_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269881112450782"},{"key":"e_1_3_2_3_39_1","unstructured":"Pharmacogenetics ethical issues. Nuffield Council on Bioethics London UK (2003)."},{"key":"e_1_3_2_3_40_1","unstructured":"Great Britain Parliament Genetic Information Nondiscrimination Act of 2008. HMSO London UK."},{"key":"e_1_3_2_3_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.tpj.6500052"},{"key":"e_1_3_2_3_42_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291702005895"},{"key":"e_1_3_2_3_43_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291702005640"},{"key":"e_1_3_2_3_44_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.106.035162"},{"key":"e_1_3_2_3_45_1","unstructured":"Great Britain Parliament The Mental Capacity Act 2005. HMSO London UK."},{"key":"e_1_3_2_3_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01499323"},{"key":"e_1_3_2_3_47_1","unstructured":"Great Britain Parliament The Mental Health Act 1983. HMSO London UK."},{"key":"e_1_3_2_3_48_1","unstructured":"Bartlett P SandlandR. Mental Health Law: Policy And Practice (2nd Edition). Oxford University Press NY USA (2003)."},{"key":"e_1_3_2_3_49_1","unstructured":"Mental Disorders and Genetics: the Ethical Context. Nuffield Council on Bioethics London UK (1998)."},{"key":"e_1_3_2_4_2_1","unstructured":"US FDA. Label approved on 07\/19\/2013 for CLOZARIL NDA no. 019758. www.accessdata.fda.gov\/drugsatfda_docs\/label\/2013\/019758s069s071lbl.pdf"},{"key":"e_1_3_2_4_3_1","unstructured":"CRESTAR \u2013 development of pharmacogenomic biomarkers for schizophrenia. www.crestar-project.eu"},{"key":"e_1_3_2_4_4_1","unstructured":"Insurance Genetics Moratorium extended to 2017. www.abi.org.uk\/News\/News-releases\/2011\/2004\/insurance-genetics-moratorium-extended-to-2017.aspx"},{"key":"e_1_3_2_4_5_1","unstructured":"Care Quality Commission. Monitoring the Mental Health Act in 2011\/12 (2013). www.cqc.org.uk\/sites\/default\/files\/media\/documents\/cqc_mentalhealth_2011_12_summary_final_web.pdf"}],"container-title":["Pharmacogenomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/pgs.13.182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T19:51:18Z","timestamp":1715975478000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/pgs.13.182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":53,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.2217\/pgs.13.182"],"URL":"https:\/\/doi.org\/10.2217\/pgs.13.182","relation":{},"ISSN":["1462-2416","1744-8042"],"issn-type":[{"value":"1462-2416","type":"print"},{"value":"1744-8042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11]]}}}