{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T11:08:17Z","timestamp":1759230497896},"reference-count":102,"publisher":"Informa UK Limited","issue":"6","funder":[{"name":"the National Nature Science Foundation, Ministry of Science and Technology of China and Shanghai City Science Foundation","award":["08dj1400503","90919002","30870805","81271003","2009CB941100","2012CB966300","2010CB945500"],"award-info":[{"award-number":["08dj1400503","90919002","30870805","81271003","2009CB941100","2012CB966300","2010CB945500"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Regen. Med."],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.2217\/rme.12.97","type":"journal-article","created":{"date-parts":[[2012,11,20]],"date-time":"2012-11-20T13:15:12Z","timestamp":1353417312000},"page":"865-875","source":"Crossref","is-referenced-by-count":9,"title":["Towards Retinal Ganglion Cell Regeneration"],"prefix":"10.1080","volume":"7","author":[{"given":"Huasong","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Fudan University Huashan Hospital, National Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen L","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Genetics, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajun","family":"Shou","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fudan University Huashan Hospital, National Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luping","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fudan University Huashan Hospital, National Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiwen","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fudan University Huashan Hospital, National Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qisheng","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fudan University Huashan Hospital, National Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiongwei","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fudan University Huashan Hospital, National Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianhong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fudan University Huashan Hospital, National Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2012,11,20]]},"reference":[{"key":"e_1_3_2_3_1_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0b013e3181e755af"},{"key":"e_1_3_2_3_2_1","first-page":"6","volume":"37","author":"Jin H","year":"2009","unstructured":"JinH, HouL, PanC. Opportunity of optic nerve decompression in treatment of traumatic optic nerve neuropathy: review of domestic literature. Clin. J. Med. Officer37 , 6\u201363 (2009).","journal-title":"Clin. J. Med. Officer"},{"key":"e_1_3_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.081224"},{"key":"e_1_3_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.124.12.1754"},{"key":"e_1_3_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.080986"},{"key":"e_1_3_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2004.01.025"},{"key":"e_1_3_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2005.04.018"},{"key":"e_1_3_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1068428"},{"key":"e_1_3_2_3_9_1","first-page":"123","volume":"9","author":"Tello F","year":"1911","unstructured":"TelloF. La influencia del neurotropismo en la regeneraci\u00f3n de los centros nerviosos. Trab. Lab. Invest. Biol. Univ. Madrid9 , 123\u2013128 (1911).","journal-title":"Trab. Lab. Invest. Biol. Univ. Madrid"},{"key":"e_1_3_2_3_10_1","doi-asserted-by":"crossref","unstructured":"Cajal\u2018s Degeneration and Regeneration of the Nervous System. Defelipe J Jones E (Eds). Oxford University Press UK (1991).","DOI":"10.1093\/acprof:oso\/9780195065169.001.0001"},{"issue":"5","key":"e_1_3_2_3_11_1","first-page":"433","volume":"5","author":"Walsh FB","year":"1966","unstructured":"WalshFB. Pathological\u2013clinical correlations. I. Indirect trauma to the optic nerves and chiasm. II. Certain cerebral involvements associated with defective blood supply. Invest. Ophthalmol.5(5) , 433\u2013449 (1966).","journal-title":"Invest. Ophthalmol."},{"key":"e_1_3_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.03-0365"},{"key":"e_1_3_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0148-11.2011"},{"key":"e_1_3_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.22584"},{"key":"e_1_3_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2006.10.013"},{"key":"e_1_3_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2010.12.008"},{"key":"e_1_3_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2010.02044.x"},{"key":"e_1_3_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2009.113"},{"key":"e_1_3_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-4310"},{"key":"e_1_3_2_3_20_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-1473"},{"key":"e_1_3_2_3_21_1","first-page":"39","article-title":"Establishment of animal model of traumatic optic neuropathy and its function evaluation by F-VEP.","volume":"28","author":"Ronggu Y","year":"2010","unstructured":"RongguY, JinguoY, ZhanshengS et al. Establishment of animal model of traumatic optic neuropathy and its function evaluation by F-VEP. Chin. Ophthalmic Res.28 , 39\u201343 (2010).","journal-title":"Chin. Ophthalmic Res."},{"key":"e_1_3_2_3_22_1","first-page":"996","volume":"38","author":"Yingjuan L","year":"2010","unstructured":"YingjuanL, XiulanZ, ShizhongW, HuaY. Expression of P53, Bax and caspase 3 after traumatic optic nerve injury in rats. Tianjin Med. J.38 , 996\u2013998 (2010).","journal-title":"Tianjin Med. J."},{"key":"e_1_3_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2011.07.012"},{"key":"e_1_3_2_3_24_1","first-page":"549","author":"Chiu K","year":"2007","unstructured":"ChiuK, ChangR, SoKF. Laser-induced chronic ocular hypertension model on SD rats. J. Vis. Exp. (10) , 549 (2007).","journal-title":"J. Vis. Exp."},{"key":"e_1_3_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2010.01.001"},{"key":"e_1_3_2_3_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2010.05.020"},{"key":"e_1_3_2_3_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2011.54"},{"key":"e_1_3_2_3_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2008.09.029"},{"key":"e_1_3_2_3_29_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4443-07.2008"},{"key":"e_1_3_2_3_30_1","first-page":"147","volume":"12","author":"Bernstein S","year":"2006","unstructured":"BernsteinS, KooJ, SlaterB, GuoY, MargolisF. Analysis of optic nerve stroke by retinal Bex expression. Mol. Vis.12 , 147\u2013155 (2006).","journal-title":"Mol. Vis."},{"key":"e_1_3_2_3_31_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08-3267"},{"key":"e_1_3_2_3_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2011.02.001"},{"key":"e_1_3_2_3_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2009.05.072"},{"key":"e_1_3_2_3_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)00084-2"},{"key":"e_1_3_2_3_35_1","first-page":"1559","volume":"14","author":"Raymond I","year":"2009","unstructured":"RaymondI, VilaA, HuynhU, BrechaN. Cyan fluorescent protein expression in ganglion and amacrine cells in a thy1-CFP transgenic mouse retina. Mol. Vis.14 , 1559\u20131574 (2009).","journal-title":"Mol. Vis."},{"key":"e_1_3_2_3_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/35053072"},{"key":"e_1_3_2_3_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/35000219"},{"key":"e_1_3_2_3_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/35000226"},{"key":"e_1_3_2_3_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/35000287"},{"key":"e_1_3_2_3_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/cdg325"},{"key":"e_1_3_2_3_41_1","first-page":"717","volume":"85","author":"Lauren J","year":"2003","unstructured":"LaurenJ, AiraksinenMS, SaarmaM, TimmuskT. Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems. Mol. Cell Neurosci.85 , 717\u2013728 (2003).","journal-title":"Mol. Cell Neurosci."},{"key":"e_1_3_2_3_42_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2003.01710.x"},{"key":"e_1_3_2_3_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(94)90247-X"},{"key":"e_1_3_2_3_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(94)90042-6"},{"key":"e_1_3_2_3_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature00867"},{"key":"e_1_3_2_3_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)00770-5"},{"key":"e_1_3_2_3_47_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2828-04.2004"},{"key":"e_1_3_2_3_48_1","doi-asserted-by":"publisher","DOI":"10.1089\/089771504774129946"},{"key":"e_1_3_2_3_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2004.01.001"},{"key":"e_1_3_2_3_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-213X-6-36"},{"key":"e_1_3_2_3_51_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0332-06.2006"},{"key":"e_1_3_2_3_52_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5317-06.2007"},{"key":"e_1_3_2_3_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/dneu.20362"},{"key":"e_1_3_2_3_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2005.08.015"},{"key":"e_1_3_2_3_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2006.00671.x"},{"key":"e_1_3_2_3_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20361"},{"key":"e_1_3_2_3_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/78774"},{"key":"e_1_3_2_3_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20290"},{"key":"e_1_3_2_3_59_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0402129101"},{"key":"e_1_3_2_3_60_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4193-06.2007"},{"key":"e_1_3_2_3_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2007.11.002"},{"key":"e_1_3_2_3_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.08.178"},{"key":"e_1_3_2_3_63_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200407053"},{"key":"e_1_3_2_3_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.wnr.0000176517.96475.18"},{"key":"e_1_3_2_3_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1657"},{"key":"e_1_3_2_3_66_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5460.2032"},{"key":"e_1_3_2_3_67_1","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2006-0541"},{"key":"e_1_3_2_3_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2003.10.021"},{"key":"e_1_3_2_3_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1088"},{"key":"e_1_3_2_3_70_1","doi-asserted-by":"publisher","DOI":"10.3727\/096368910X492625"},{"key":"e_1_3_2_3_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-011-1635-7"},{"key":"e_1_3_2_3_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6701577"},{"key":"e_1_3_2_3_73_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713680600681210"},{"key":"e_1_3_2_3_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0463.2005.apm_334.x"},{"key":"e_1_3_2_3_75_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e3180391a18"},{"key":"e_1_3_2_3_76_1","doi-asserted-by":"publisher","DOI":"10.2217\/rme.09.59"},{"key":"e_1_3_2_3_77_1","doi-asserted-by":"publisher","DOI":"10.3129\/i10-077"},{"key":"e_1_3_2_3_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(08)01135-7"},{"key":"e_1_3_2_3_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-007-0710-6"},{"key":"e_1_3_2_3_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.320"},{"key":"e_1_3_2_3_81_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-4509"},{"key":"e_1_3_2_3_82_1","doi-asserted-by":"publisher","DOI":"10.1006\/mcne.2000.0869"},{"issue":"13","key":"e_1_3_2_3_83_1","first-page":"4268","article-title":"Incorporation and differentiation of hippocampus-derived neural stem cells transplanted in injured adult rat retina.","volume":"41","author":"Nishida A","year":"2000","unstructured":"NishidaA, TakahashiM, TaniharaH et al. Incorporation and differentiation of hippocampus-derived neural stem cells transplanted in injured adult rat retina. Invest. Ophthalmol. Vis. Sci.41(13) , 4268\u20134274 (2000).","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"e_1_3_2_3_84_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-0511"},{"key":"e_1_3_2_3_85_1","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.20-2-163"},{"key":"e_1_3_2_3_86_1","doi-asserted-by":"publisher","DOI":"10.1006\/exer.2001.1172"},{"key":"e_1_3_2_3_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00005657"},{"key":"e_1_3_2_3_88_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5274.510"},{"key":"e_1_3_2_3_89_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.09-11-04042.1989"},{"key":"e_1_3_2_3_90_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2799387"},{"key":"e_1_3_2_3_91_1","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2005-0009"},{"key":"e_1_3_2_3_92_1","doi-asserted-by":"publisher","DOI":"10.3727\/096368910X524764"},{"key":"e_1_3_2_3_93_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.16-04-01294.1996"},{"key":"e_1_3_2_3_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4886(02)00058-4"},{"key":"e_1_3_2_3_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-328X(01)00044-4"},{"key":"e_1_3_2_3_96_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-1136(200103)33:3<225::AID-GLIA1021>3.0.CO;2-Y"},{"key":"e_1_3_2_3_97_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18-10-03803.1998"},{"key":"e_1_3_2_3_98_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-21-07783.2003"},{"key":"e_1_3_2_3_99_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08-1770"},{"issue":"2","key":"e_1_3_2_3_100_1","first-page":"177","volume":"25","author":"Mellough CB","year":"2007","unstructured":"MelloughCB, CuiQ, HarveyAR. Treatment of adult neural progenitor cells prior to transplantation affects graft survival and integration in a neonatal and adult rat model of selective retinal ganglion cell depletion. Restor. Neurol. Neurosci.25(2) , 177\u2013190 (2007).","journal-title":"Restor. Neurol. Neurosci."},{"key":"e_1_3_2_3_101_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-0875"},{"issue":"10","key":"e_1_3_2_3_102_1","first-page":"3210","volume":"41","author":"Chiang SK","year":"2000","unstructured":"ChiangSK, LamTT. Post-treatment at 12 or 18 hours with 3-aminobenzamide ameliorates retinal ischemia-reperfusion damage. Invest. Ophthalmol. Vis. Sci.41(10) , 3210\u20133214 (2000).","journal-title":"Invest. Ophthalmol. Vis. Sci."}],"container-title":["Regenerative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/rme.12.97","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T18:28:34Z","timestamp":1715970514000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/rme.12.97"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":102,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.2217\/rme.12.97"],"URL":"https:\/\/doi.org\/10.2217\/rme.12.97","relation":{},"ISSN":["1746-0751","1746-076X"],"issn-type":[{"value":"1746-0751","type":"print"},{"value":"1746-076X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}