{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T04:26:21Z","timestamp":1770265581802,"version":"3.49.0"},"reference-count":64,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Womens Health (Lond Engl)"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:p> Health burden related to osteoporotic fractures in an aging female population far exceeds that imposed by other chronic disorders such as cardiovascular disease and breast cancer. Bone mineral density assessment and clinical risk factors provide independent insights into fracture risk in individuals. A finite list of clinical risk factors are identified as prognostic of fracture risk, namely among aging women, including low body mass, compromised reproductive physiology (e.g., prolonged periods of amenorrhea and early menopause), parental and personal histories of fracture, and alcohol and tobacco use. Pelvic organ prolapse is a common gynecologic entity and a contributor to age-related morbidities. The purpose of this review is to communicate data identifying pelvic organ prolapse as another clinical risk factor for fracture risk in postmenopausal women and to increase the caregiver's vigilance in anticipating and instituting preventive care strategies to a population (i.e., postmenopausal women with clinically appreciable pelvic organ prolapse) that may be at an enhanced lifetime risk for skeletal fractures. <\/jats:p>","DOI":"10.2217\/whe.09.19","type":"journal-article","created":{"date-parts":[[2009,4,24]],"date-time":"2009-04-24T15:04:54Z","timestamp":1240585494000},"page":"325-333","source":"Crossref","is-referenced-by-count":4,"title":["Pelvic Organ Prolapse and Relationship with Skeletal Integrity"],"prefix":"10.1177","volume":"5","author":[{"given":"Lubna","family":"Pal","sequence":"first","affiliation":[{"name":"Lubna Pal, MBBS, MRCOG, MSc Assistant Professor, Department of Obstetrics, Gynecology & Reproductive Sciences, Yale University School of Medicine, New Haven CT, USA, Tel.: +1 203 785 4016, Fax: +1 203 785 7134,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,5,1]]},"reference":[{"key":"bibr00101-WHE.09.19","unstructured":"Papers of special note have been highlighted as:"},{"key":"bibr00102-WHE.09.19","unstructured":"of interest"},{"key":"bibr00103-WHE.09.19","unstructured":"of considerable interest"},{"key":"bibr1-WHE.09.19","first-page":"1","volume":"13","author":"Popovic JR","year":"1998","journal-title":"Vital Health Stat."},{"key":"bibr2-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2008.09.002"},{"key":"bibr3-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2008.07.003"},{"key":"bibr0107-WHE.09.19","unstructured":"\u2022 Excellent review regarding bone matrix and archictectural contributions to overall skeletal integrity."},{"key":"bibr4-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-7404(02)00016-6"},{"key":"bibr5-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2008.04.003"},{"key":"bibr01010-WHE.09.19","unstructured":"\u2022\u2022 Fracture risk assessment tool provides population and race-adjusted individualized 10-year absolute fracture risk (for any osteoporotic fracture as well as for hip fracture)."},{"key":"bibr6-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1541-9215.2007.06350.x"},{"key":"bibr7-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(02)00815-3"},{"key":"bibr01013-WHE.09.19","unstructured":"\u2022 Excellent review of bone matrix and archictectural contributions to overall skeletal integrity."},{"key":"bibr8-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1999.14.3.330"},{"key":"bibr9-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.105410"},{"key":"bibr01016-WHE.09.19","unstructured":"\u2022 Identifies gynecological issues in women with generalized connective tissue disorders."},{"key":"bibr10-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90351-O"},{"key":"bibr01018-WHE.09.19","unstructured":"\u2022 Identifies skeletal concerns in women with generalized connective tissue disorders."},{"key":"bibr11-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1007\/s001980070104"},{"key":"bibr120-WHE.09.19","unstructured":"\u2022 Identifies skeletal concerns in women with generalized connective tissue disorders."},{"key":"bibr12-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(68)90325-6"},{"key":"bibr13-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-36730"},{"key":"bibr14-WHE.09.19","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.123819"},{"key":"bibr01024-WHE.09.19","unstructured":"\u2022\u2022 Excellent overview of the prevalence of pelvic organ prolapse (POP) in postmenopausal population in the USA."},{"issue":"4","key":"bibr15-WHE.09.19","first-page":"646","volume":"98","author":"Subak LL","year":"2001","journal-title":"Obstet. 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