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The morbidity of SLNB is far less than traditional inguinofemoral lymphadenectomy, with less lymphedema and sensory deficit, shorter hospital stays and fewer infections. A multidisciplinary approach is required, with success of the SLNB technique maximized when radiolabeled colloid is used, with blue dye added when further identification is needed. Frozen-section analysis, followed by ultrastaging of the nodal sample, minimizes the need for reoperations and decreases the risk of false negatives. We believe that SLNB will become the standard of care for treatment of early-stage vulvar carcinoma. <\/jats:p>","DOI":"10.2217\/whe.09.37","type":"journal-article","created":{"date-parts":[[2010,2,3]],"date-time":"2010-02-03T09:09:59Z","timestamp":1265188199000},"page":"555-563","source":"Crossref","is-referenced-by-count":1,"title":["State of the Art of Sentinel Lymph Node Biopsy in Vulvar Carcinoma"],"prefix":"10.1177","volume":"5","author":[{"given":"Jacob","family":"McGee","sequence":"first","affiliation":[{"name":"Allan Covens, MD, FRCSC, Odette Cancer Center, 2075 Bayview Ave T2051, Toronto, Ontario, M4N 3M5, Canada, and, Division of Gynecologic Oncology, Sunnybrook Health Sciences Center, University of Toronto, Canada, Tel.: +1 416 480 4026, Fax: +1 416 490 6002,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan","family":"Covens","sequence":"additional","affiliation":[{"name":"Jacob McGee, Division of Gynecologic Oncology, Sunnybrook Health Sciences Center, University of Toronto, Canada, Tel.: +1 647 449 3268,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,9,1]]},"reference":[{"key":"bibr0101-WHE.09.37","unstructured":"Papers of special note have been highlighted as:"},{"key":"bibr0102-WHE.09.37","unstructured":"of interest"},{"key":"bibr0103-WHE.09.37","unstructured":"of considerable interest"},{"key":"bibr1-WHE.09.37","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.54.1.8"},{"volume-title":"Clinical Gynecologic Oncology.","year":"2007","author":"DiSaia P","key":"bibr2-WHE.09.37"},{"key":"bibr3-WHE.09.37","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(79)90119-4"},{"issue":"4","key":"bibr4-WHE.09.37","first-page":"457","volume":"62","author":"Andersen BL","year":"1983","journal-title":"Obstet. 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