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Data from these trials, and one meta-analysis, suggest that aspirin prevents myocardial infarction in men and stroke in women, although the findings in women were driven by the results of a single large study, and a subsequent meta-analysis did not find a gender difference. The reasons for the possible gender differences in aspirin's effectiveness are not entirely clear. <\/jats:p>","DOI":"10.2217\/whe.11.21","type":"journal-article","created":{"date-parts":[[2011,5,25]],"date-time":"2011-05-25T15:47:29Z","timestamp":1306338449000},"page":"341-353","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Gender Differences in the Primary Prevention of Stroke with Aspirin"],"prefix":"10.1177","volume":"7","author":[{"given":"Eric E","family":"Adelman","sequence":"first","affiliation":[{"name":"Stroke Program, Department of Neurology, University of Michigan, Cardiovascular Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynda","family":"Lisabeth","sequence":"additional","affiliation":[{"name":"Stroke Program, Department of Neurology, University of Michigan, Cardiovascular Center, 1500 East Medical Center 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