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In a systematic search of the literature, we identified nine prognostic studies, of which we assessed the quality, the different phases of development and their performance. From these data, we identified the most important predictor variables. None of the detected models completed external validation or impact analysis. Models including power Doppler showed best performance in internal validation, but Doppler in general gynecological practice is not easily accessible. We can conclude that we have indications that the first step in the approach of women with postmenopausal bleeding should be to distinguish between women with low risk versus high risk of having endometrial carcinoma and the next step would be to refer patients for further (invasive) testing. <\/jats:p>","DOI":"10.2217\/whe.12.10","type":"journal-article","created":{"date-parts":[[2012,5,3]],"date-time":"2012-05-03T13:57:05Z","timestamp":1336053425000},"page":"251-262","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Prediction Models in Women with Postmenopausal Bleeding: A Systematic Review"],"prefix":"10.1177","volume":"8","author":[{"given":"Nehalennia","family":"van Hanegem","sequence":"first","affiliation":[{"name":"Department of Obstetrics & Gynecology, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, the Netherlands"},{"name":"Department of Obstetrics & Gynecology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C","family":"Breijer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, the Netherlands"},{"name":"Department of Obstetrics & Gynecology, Albert Schweitzer Hospital, Dordrecht, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent C","family":"Opmeer","sequence":"additional","affiliation":[{"name":"Clinical Research Unit, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben WJ","family":"Mol","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Timmermans","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,5,1]]},"reference":[{"unstructured":"Papers of special note have been highlighted as:","key":"bibr1a-WHE.12.10"},{"unstructured":"of interest.","key":"bibr2a-WHE.12.10"},{"unstructured":"of considerable interest.","key":"bibr3a-WHE.12.10"},{"doi-asserted-by":"publisher","key":"bibr1-WHE.12.10","DOI":"10.1016\/S0002-9378(96)80082-2"},{"volume-title":"Diagnostics in Abnormal Vaginal Blood Loss in the Postmenopausal Period","year":"2003","key":"bibr2-WHE.12.10"},{"doi-asserted-by":"publisher","key":"bibr3-WHE.12.10","DOI":"10.1016\/0029-7844(95)00450-5"},{"key":"bibr4-WHE.12.10","first-page":"237","volume":"4","author":"Emanuel M","year":"1995","journal-title":"Gynecol. 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