{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:18:30Z","timestamp":1762521510645,"version":"3.38.0"},"reference-count":39,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Womens Health (Lond Engl)"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p> Polycystic ovary syndrome (PCOS) has been managed surgically since the development of wedge resection in the 1930s. Second-line surgical interventions for anovulation associated with PCOS include laparoscopic ovarian diathermy, which is as effective as medical induction of ovulation with gonadotropins, with a much reduced risk of multiple pregnancy. Bariatric surgery may be considered for morbidly obese patients with PCOS, although further research assessing such surgery specifically in PCOS patients is needed. Assisted reproduction, in the form of IVF with or without intracytoplasmic sperm injection, is usually indicated as third-line medical treatment or in the presence of other infertility factors. There is an ongoing debate concerning the relative merits of IVF and ovulation induction in PCOS, comparing the higher multiple pregnancy rate of ovulation induction with the greater cost and psychological stress of IVF. <\/jats:p>","DOI":"10.2217\/whe.12.7","type":"journal-article","created":{"date-parts":[[2012,5,3]],"date-time":"2012-05-03T13:57:05Z","timestamp":1336053425000},"page":"291-300","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Evidence-Based Management of Infertility in Women with Polycystic Ovary Syndrome Using Surgery or Assisted Reproductive Technology"],"prefix":"10.1177","volume":"8","author":[{"given":"Michael F","family":"Costello","sequence":"first","affiliation":[{"name":"School of Women's & Children's Health, Division of Obstetrics & Gynaecology, University of New South Wales, Level 1 Women's Health Institute, Royal Hospital for Women, Locked Bag 2000, Randwick, Sydney, NSW 2031, Australia and Department of Reproductive Medicine & IVF Australia, Royal Hospital for Women, Sydney, NSW, Australia, Tel.: +61 2 9382 6677, Fax: +61 2 9382 6444, , Tel.: +61 2 9382 6731, Fax: +61 2 9382 6556,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William L","family":"Ledger","sequence":"additional","affiliation":[{"name":"School of Women's & Children's Health, Division of Obstetrics & Gynaecology, University of New South Wales, Level 1 Women's Health Institute, Royal Hospital for Women, Locked Bag 2000, Randwick, Sydney, NSW 2031, Australia and Department of Reproductive Medicine & IVF Australia, Royal Hospital for Women, Sydney, NSW, Australia, Tel.: +61 2 9382 6677, Fax: +61 2 9382 6444, , Tel.: +61 2 9382 6731, Fax: +61 2 9382 6556,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,5,1]]},"reference":[{"key":"bibr1a-WHE.12.7","unstructured":"Papers of special note have been highlighted as:"},{"key":"bibr2a-WHE.12.7","unstructured":"of interest."},{"key":"bibr3a-WHE.12.7","unstructured":"of considerable interest."},{"key":"bibr1-WHE.12.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(15)30642-6"},{"key":"bibr2-WHE.12.7","doi-asserted-by":"publisher","DOI":"10.1097\/01.gco.0000193020.82814.9d"},{"key":"bibr3-WHE.12.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)47534-5"},{"key":"bibr4-WHE.12.7","first-page":"CD001122","volume":"3","author":"Farquhar C","year":"2007","journal-title":"Cochrane Database Syst. 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