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Its diagnosis is mainly based on careful clinical judgment, although it may require additional investigation by blood testing or imaging techniques in the differential diagnosis of androgen excess. This article summarizes the most important aspects of the diagnostic procedure and suggests how to apply them in clinical practice. <\/jats:p>","DOI":"10.2217\/whe.15.13","type":"journal-article","created":{"date-parts":[[2015,3,10]],"date-time":"2015-03-10T17:02:27Z","timestamp":1426006947000},"page":"501-512","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["A Comprehensive Approach in Diagnosing the Polycystic Ovary Syndrome"],"prefix":"10.1177","volume":"11","author":[{"given":"Renato","family":"Pasquali","sequence":"first","affiliation":[{"name":"Endocrinology Unit, Department of Medical & Surgical Sciences, University Alma Mater Studiorum of Bologna, S Orsoia-Maipighi Hospital, 40138 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Gambineri","sequence":"additional","affiliation":[{"name":"Endocrinology Unit, Department of Medical & Surgical Sciences, University Alma Mater Studiorum of Bologna, S Orsoia-Maipighi Hospital, 40138 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,7,1]]},"reference":[{"key":"bibr1a-WHE.15.13","unstructured":"Papers of special note have been highlighted as: \u2022 of interest; \u2022\u2022 of considerable interest."},{"key":"bibr1-WHE.15.13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041536"},{"key":"bibr2-WHE.15.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(15)30642-6"},{"key":"bibr3-WHE.15.13","first-page":"377","volume-title":"Polycystic Ovary Syndrome.","author":"Zawadzki JK","year":"1992"},{"key":"bibr4-WHE.15.13","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh098"},{"key":"bibr5-WHE.15.13","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0178"},{"key":"bibr6-WHE.15.13","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-2040"},{"key":"bibr8a-WHE.15.13","unstructured":"This article focuses on the need to identify specific phenotypes of polycystic ovary syndrome (PCOS), and suggests potential strategies for clinical management and research development."},{"key":"bibr7-WHE.15.13","doi-asserted-by":"publisher","DOI":"10.1159\/000341682"},{"key":"bibr8-WHE.15.13","unstructured":"National Institute of Health. 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