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Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics. J Exp Med 181:1365-1372, 1995."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Sez-Cirin A, Lacabaratz C, Lambotte O, Versmisse P, Urrutia A, Boufassa F, Barr-Sinoussi F, Delfraissy JF, Sinet M, Pancino G, and Venet A; Agence Nationale de Recherches sur le Sida EP36 HIV Controllers Study Group. HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype. Proc Natl Acad Sci U S A 104:6776-6781, 2007.","DOI":"10.1073\/pnas.0611244104"},{"key":"3","unstructured":"3) Sez-Cirin A, Sinet M, Shin SY, Urrutia A, Versmisse P, Lacabaratz C, Boufassa F, Avettand-Fnol V, Rouzioux C, Delfraissy JF, Barr-Sinoussi F, Lambotte O, Venet A, and Pancino G; ANRS EP36 HIV Controllers Study Group. Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses. J Immunol 182:7828-7837, 2009."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Chen H, Ndhlovu ZM, Liu D, Porter LC, Fang JW, Darko S, Brockman MA, Miura T, Brumme ZL, Schneidewind A, Piechocka-Trocha A, Cesa KT, Sela J, Cung TD, Toth I, Pereyra F, Yu XG, Douek DC, Kaufmann DE, Allen TM, and Walker BD. TCR clonotypes modulate the protective effect of HLA class I molecules in HIV infection. Nat Immunol 13:691-700, 2012.","DOI":"10.1038\/ni.2342"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, Shin LY, Kovacs CM, Rodriguez B, Sieg SF, Teixeira-Johnson L, Gudonis D, Goepfert PA, Lederman MM, Frank I, Makedonas G, Kaul R, Walker BD, and Betts MR. Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. PLoS Pathog 6:e1000917, 2010.","DOI":"10.1371\/journal.ppat.1000917"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, Weeks KA, Rood JE, Berkley AM, Sacha JB, Cogliano-Shutta NA, Lloyd M, Roby G, Kwan R, McLaughlin M, Stallings S, Rehm C, O'Shea MA, Mican J, Packard BZ, Komoriya A, Palmer S, Wiegand AP, Maldarelli F, Coffin JM, Mellors JW, Hallahan CW, Follman DA, and Connors M. Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control. Immunity 29:1009-1021, 2008.","DOI":"10.1016\/j.immuni.2008.10.010"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Migueles SA, Laborico AC, Shupert WL, Sabbaghian MS, Rabin R, Hallahan CW, Van Baarle D, Kostense S, Miedema F, McLaughlin M, Ehler L, Metcalf J, Liu S, and Connors M. HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors. Nature Immunol 3:1061-1068, 2002.","DOI":"10.1038\/ni845"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Zimmerli SC, Harari A, Cellerai C, Vallelian F, Bart PA, and Pantaleo G. HIV-1-specific IFN-\u03b3\/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells. Proc Natl Acad Sci U S A 102:7239-7244, 2005.","DOI":"10.1073\/pnas.0502393102"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, Moodley E, Reddy S, de Pierres C, Mncube Z, Mkhwanazi N, Bishop K, van der Stok M, Nair K, Khan N, Crawford H, Payne R, Leslie A, Prado J, Prendergast A, Frater J, McCarthy N, Brander C, Learn GH, Nickle D, Rousseau C, Coovadia H, Mullins JI, Heckerman D, Walker BD, and Goulder P. CD8+ T cell responses to different HIV proteins have discordant associations with viral load. Nature Med 13:46-53, 2007.","DOI":"10.1038\/nm1520"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Zuiga R, Lucchetti A, Galvan P, Sanchez S, Sanchez C, Hernandez A, Sanchez H, Frahm N, Linde CH, Hewitt HS, Hildebrand W, Altfeld M, Allen TM, Walker BD, Korber BT, Leitner T, Sanchez J, and Brander C. Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control. J Virol 80:3122-3125, 2006.","DOI":"10.1128\/JVI.80.6.3122-3125.2006"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Edwards BH, Bansal A, Sabbaj S, Bakari J, Mulligan MJ, and Goepfert PA. Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma. J Virol 76:2298-2305, 2002.","DOI":"10.1128\/jvi.76.5.2298-2305.2002"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Novitsky VA, Gilbert PB, Shea K, McLane MF, Rybak N, Klein I, Thior I, Ndung'u T, Lee TH, and Essex ME. Interactive association of proviral load and IFN-\u03b3-secreting T cell responses in HIV-1C infection. Virology 349:142-155, 2006.","DOI":"10.1016\/j.virol.2006.02.006"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Addo MM, Yu XG, Rathod A, Cohen D, Eldridge RL, Strick D, Johnston MN, Corcoran C, Wurcel AG, Fitzpatrick CA, Feeney ME, Rodriguez WR, Basgoz N, Draenert R, Stone DR, Brander C, Goulder PJ, Rosenberg ES, Altfeld M, and Walker BD. Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. J Virol 77:2081-2092, 2003.","DOI":"10.1128\/JVI.77.3.2081-2092.2003"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Feeney ME, Roosevelt KA, Tang Y, Pfafferott KJ, McIntosh K, Burchett SK, Mao C, Walker BD, and Goulder PJ. Comprehensive screening reveals strong and broadly directed human immunodeficiency virus type 1-specific CD8 responses in perinatally infected children. J Virol 77: 7492-7501, 2003.","DOI":"10.1128\/JVI.77.13.7492-7501.2003"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Frahm N, Korber BT, Adams CM, Szinger JJ, Draenert R, Addo MM, Feeney ME, Yusim K, Sango K, Brown NV, SenGupta D, Piechocka-Trocha A, Simonis T, Marincola FM, Wurcel AG, Stone DR, Russell CJ, Adolf P, Cohen D, Roach T, StJohn A, Khatri A, Davis K, Mullins J, Goulder PJ, Walker BD, and Brander C. Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities. 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J Virol 81: 6742-6751, 2007.","DOI":"10.1128\/JVI.00022-07"},{"key":"18","unstructured":"18) Masemola A, Mashishi T, Khoury G, Mohube P, Mokgotho P, Vardas E, Colvin M, Zijenah L, Katzenstein D, Musonda R, Allen S, Kumwenda N, Taha T, Gray G, McIntyre J, Karim SA, Sheppard HW, and Gray CM; HIVNET 028 Study Team. Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load. J Virol 78:3233-3243, 2004."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Huang S, Dunkley-Thompson J, Tang Y, Macklin EA, Steel-Duncan J, Singh-Minott I, Ryland EG, Smikle M, Walker BD, Christie CD, and Feeney ME. Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containment. J Immunol 181:8103-8111, 2008.","DOI":"10.4049\/jimmunol.181.11.8103"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Emu B, Sinclair E, Hatano H, Ferre A, Shacklett B, Martin JN, McCune JM, and Deeks SG. HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J Virol 82:5398-5407, 2008.","DOI":"10.1128\/JVI.02176-07"},{"key":"21","unstructured":"21) Goulder PJ and Walker BD. HIV and HLA class I: an evolving relationship. Immunity 37:426-40, 2012."},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Ammaranond P, van Bockel DJ, Petoumenos K, McMurchie M, Finlayson R, Middleton MG, Davenport MP, Venturi V, Suzuki K, Gelgor L, Kaldor JM, Cooper DA, and Kelleher AD. HIV immune escape at an immunodominant epitope in HLA-B*27-positive individuals predicts viral load outcome. J Immunol 186:479-488, 2011.","DOI":"10.4049\/jimmunol.0903227"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Feeney ME, Tang Y, Roosevelt KA, Leslie AJ, McIntosh K, Karthas N, Walker BD, and Goulder PJ. 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J Virol 84: 7151-7160, 2010.","DOI":"10.1128\/JVI.00171-10"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Ladell K, Hashimoto M, Iglesias MC, Wilmann PG, McLaren JE, Gras S, Chikata T, Kuse N, Fastenackels S, Gostick E, Bridgeman JS, Venturi V, Arkoub ZA, Agut H, van Bockel DJ, Almeida JR, Douek DC, Meyer L, Venet A, Takiguchi M, Rossjohn J, Price DA, and Appay V. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 38:425-436, 2013.","DOI":"10.1016\/j.immuni.2012.11.021"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Tomiyama H, Fujiwara M, Oka S, and Takiguchi M. Epitope-dependent effect of Nef-mediated HLA class I down-regulation on ability of HIV-specific CTLs to suppress HIV replication. J Immunol 174:36-40, 2005.","DOI":"10.4049\/jimmunol.174.1.36"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Naruto T, Gatanaga H, Nelson G, Sakai K, Carrington M, Oka S, and Takiguchi M. HLA class I-mediated control of HIV in the Japanese population, in which the protective HLA-B*57 and HLA-B*27 alleles are absent. J Virol 86 :10870-10872, 2012.","DOI":"10.1128\/JVI.00689-12"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Borrow P, Lewicki H, Wei X, Horwitz MS, Peffer N, Meyers H, Nelson JA, Gairin JE, Hahn BH, Oldstone MB, and Shaw GM. Antiviral pressure exerted by HIV-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nat Med 3:205-211, 1997.","DOI":"10.1038\/nm0297-205"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Ammaranond P, Zaunders J, Satchell C, van Bockel D, Cooper DA, and Kelleher AD. A new variant cytotoxic T lymphocyte escape mutation in HLA-B27-positive individuals infected with HIV type 1. AIDS Res Hum Retroviruses 21:395-397, 2005.","DOI":"10.1089\/aid.2005.21.395"},{"key":"31","unstructured":"31) Leslie AJ, Pfafferott KJ, Chetty P, Draenert R, Addo MM, Feeney M, Tang Y, Holmes EC, Allen T, Prado JG, Altfeld M, Brander C, Dixon C, Ramduth D, Jeena P, Thomas SA, St John A, Roach TA, Kupfer B, Luzzi G, Edwards A, Taylor G, Lyall H, Tudor-Williams G, Novelli V, Martinez-Picado J, Kiepiela P, Walker BD, and Goulder PJ. HIV evolution: CTL escape mutation and reversion after transmission. Nat Med 10:282-289, 2004."},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Crawford H, Lumm W, Leslie A, Schaefer M, Boeras D, Prado JG, Tang J, Farmer P, Ndung'u T, Lakhi S, Gilmour J, Goepfert P, Walker BD, Kaslow R, Mulenga J, Allen S, Goulder PJ, and Hunter E. Evolution of HLA-B*5703 HIV escape mutations in HLA-B*5703-positive individuals and their transmission recipients. J Exp Med 206:909-921, 2009.","DOI":"10.1084\/jem.20081984"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Kawashima Y, Pfafferott K, Frater J, Matthews P, Payne R, Addo M, Gatanaga H, Fujiwara M, Hachiya A, Koizumi H, Kuse N, Oka S, Duda A, Prendergast A, Crawford H, Leslie A, Brumme Z, Brumme C, Allen T, Brander C, Kaslow R, Tang J, Hunter E, Allen S, Mulenga J, Branch S, Roach T, John M, Mallal S, Ogwu A, Shapiro R, Prado JG, Fidler S, Weber J, Pybus OG, Klenerman P, Ndung'u T, Phillips R, Heckerman D, Harrigan PR, Walker BD, Takiguchi M, and Goulder P. Adaptation of HIV to human leukocyte antigen class I. 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