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In this manuscript, we present numerical techniques inspired by Nonperturbative Analytical Diagonalization (NPAD) and the Magnus expansion for the efficient calculation of effective Hamiltonians. While these tools are appropriate for a wide array of applications, we here demonstrate their utility for models that can be realized in circuit-QED settings. Our numerical techniques are available as an open-source Python package,\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\">\n                      <mml:msub>\n                        <mml:mtext>qCH<\/mml:mtext>\n                        <mml:mtext>eff<\/mml:mtext>\n                      <\/mml:msub>\n                    <\/mml:math>\n                    , which is available on GitHub  and PyPI. We use the CuPy library for GPU-acceleration and report up to 15x speedup on GPU over CPU for NPAD, and up to 42x speedup for the Magnus expansion (compared to QuTiP), for large system sizes.\n                  <\/jats:p>","DOI":"10.22331\/q-2025-12-15-1946","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T10:21:01Z","timestamp":1765794061000},"page":"1946","update-policy":"https:\/\/doi.org\/10.22331\/q-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["GPU-accelerated Effective Hamiltonian Calculator"],"prefix":"10.22331","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9483-3394","authenticated-orcid":false,"given":"Abhishek","family":"Chakraborty","sequence":"first","affiliation":[{"name":"NVIDIA, Santa Clara, California 95051, USA"},{"name":"Center for Coherence and Quantum Science (CCQS), University of Rochester, Rochester, NY 14627, USA"},{"name":"Department of Physics and Astronomy, University of Rochester, Rochester, NY 14627, USA"},{"name":"Institute for Quantum Studies (IQS), Chapman University, Orange, CA 92866, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4242-6072","authenticated-orcid":false,"given":"Taylor L.","family":"Patti","sequence":"additional","affiliation":[{"name":"NVIDIA, Santa Clara, California 95051, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7584-3489","authenticated-orcid":false,"given":"Brucek","family":"Khailany","sequence":"additional","affiliation":[{"name":"NVIDIA, Santa Clara, California 95051, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9646-7013","authenticated-orcid":false,"given":"Andrew N.","family":"Jordan","sequence":"additional","affiliation":[{"name":"Center for Coherence and Quantum Science (CCQS), University of Rochester, Rochester, NY 14627, USA"},{"name":"Department of Physics and Astronomy, University of Rochester, Rochester, NY 14627, USA"},{"name":"Institute for Quantum Studies (IQS), Chapman University, Orange, CA 92866, USA"},{"name":"The Kennedy Chair in Physics, Chapman University, Orange, CA 92866, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6974-6797","authenticated-orcid":false,"given":"Anima","family":"Anandkumar","sequence":"additional","affiliation":[{"name":"Department of Computing + Mathematical Sciences (CMS), California Institute of Technology (Caltech), Pasadena, CA 91125, USA"}]}],"member":"9598","published-online":{"date-parts":[[2025,12,15]]},"reference":[{"key":"0","doi-asserted-by":"publisher","unstructured":"Flemming J\u00f8rgensen. ``Effective hamiltonians&apos;&apos;. 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