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A simple model exhibiting this physics is the transverse-field Ising model, which can host a topological defect that performs the Kramers-Wannier duality transformation. When acting on one point in space, this duality defect imposes the duality twisted boundary condition and binds a single zero mode. This zero mode is unusual as it lacks a localized partner in the same\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\">\n                      <mml:msub>\n                        <mml:mrow class=\"MJX-TeXAtom-ORD\">\n                          <mml:mi mathvariant=\"double-struck\">Z<\/mml:mi>\n                        <\/mml:mrow>\n                        <mml:mn>2<\/mml:mn>\n                      <\/mml:msub>\n                    <\/mml:math>\n                    sector and has an infinite lifetime, even in finite systems. Using Floquet driving of a closed Ising chain with a duality defect, we generate this zero mode in a digital quantum computer. We detect the mode by measuring its associated persistent autocorrelation function using an efficient sampling protocol and a compound strategy for error mitigation. We also show that the zero mode resides at the domain wall between two regions related by a Kramers-Wannier duality transformation. Finally, we highlight the robustness of the isolated zero mode to integrability- and symmetry-breaking perturbations. Our findings provide a method for exploring exotic topological defects, associated with noninvertible generalized symmetries, in digitized quantum devices.\n                  <\/jats:p>","DOI":"10.22331\/q-2025-12-30-1957","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T08:39:53Z","timestamp":1767083993000},"page":"1957","update-policy":"https:\/\/doi.org\/10.22331\/q-crossmark-policy-page","source":"Crossref","is-referenced-by-count":1,"title":["Isolated zero mode in a quantum computer from a duality twist"],"prefix":"10.22331","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1872-1864","authenticated-orcid":false,"given":"Sutapa","family":"Samanta","sequence":"first","affiliation":[{"name":"Department of Physics and Astronomy, Western Washington University, Bellingham, Washington 98225, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek S.","family":"Wang","sequence":"additional","affiliation":[{"name":"IBM Quantum, IBM T.J. Watson Research Center, Yorktown Heights, New York 10598, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armin","family":"Rahmani","sequence":"additional","affiliation":[{"name":"Department of Physics and Astronomy, Western Washington University, Bellingham, Washington 98225, USA"},{"name":"Advanced Materials Science and Engineering Center, Western Washington University, Bellingham, Washington 98225, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2169-3796","authenticated-orcid":false,"given":"Aditi","family":"Mitra","sequence":"additional","affiliation":[{"name":"Center for Quantum Phenomena, Department of Physics, New York University, 726 Broadway, New York, New York 10003, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"9598","published-online":{"date-parts":[[2025,12,30]]},"reference":[{"key":"0","doi-asserted-by":"publisher","unstructured":"Emilio Cobanera, Gerardo Ortiz, and Zohar Nussinov. ``The bond-algebraic approach to dualities&apos;&apos;. 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