{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T17:59:30Z","timestamp":1713981570260},"reference-count":0,"publisher":"MRE Press","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:p>This case series aimed to assess the treatment outcomes of onabotulinum toxin A (BTX-A) in patients with refractory posttraumatic trigeminal neuropathic pain (PTNP) and to conduct a narrative review of the evidence for BTX-A in PTNP. Thirteen patients were treated with BTX-A infiltrations. Patient demographic and pain characteristics, BTX-A administration, and treatment outcomes were retrospectively analyzed. Papers retrieved after a literature search of articles on PTNP treatment using BTX-A were reviewed. Six patients reported an improvement in pain 3 months after the initial BTX-A injection, with 4 patients reporting a 50% reduction. Two patients achieved an 80% reduction in pain score over 3 years of BTX-A therapy. Three patients reported temporary ipsilateral facial muscle weakness. The literature review revealed five case reports on the use of BTX-A in PTNP patients that reported similar effectiveness to the present cohort study. BTX-A may be a potential treatment modality for refractory PTNP, thus reducing the need for polypharmacy. Multiple intraoral BTX-A injections administered over the painful sites are well tolerated, safe and easily practiced. High-quality studies are required to evaluate the long-term therapeutic efficacy and side effects of BTX-A therapy.<\/jats:p>","DOI":"10.22514\/jofph.2024.009","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T01:14:40Z","timestamp":1710292480000},"source":"Crossref","is-referenced-by-count":0,"title":["Onabotulinum toxin a treatment for posttraumatic trigeminal neuropathic pain: case series and literature review"],"prefix":"10.22514","member":"26027","published-online":{"date-parts":[[2024]]},"container-title":["Journal of Oral &amp; Facial Pain and Headache"],"original-title":[],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T01:14:40Z","timestamp":1710292480000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jofph.com\/articles\/10.22514\/jofph.2024.009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":0,"URL":"https:\/\/doi.org\/10.22514\/jofph.2024.009","relation":{},"ISSN":["2333-0376","2333-0384"],"issn-type":[{"value":"2333-0376","type":"electronic"},{"value":"2333-0384","type":"print"}],"subject":[],"published":{"date-parts":[[2024]]}}}