{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"Authorea, Inc."}],"indexed":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T16:40:07Z","timestamp":1748968807551,"version":"3.41.0"},"posted":{"date-parts":[[2023,4,21]]},"group-title":"Preprints","reference-count":0,"publisher":"Wiley","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2023,4,21]]},"abstract":"<jats:p id=\"p1\">Aim. To investigate the impact of pharmacists\u2019 presence in long-term\ncare facilities (LTCFs) on medication usage. Methods. The study followed\na retrospective cohort design, with a sample of patients aged \u2265 65 years\nold admitted to 3 LTCFs over 30 months. Data on age, gender, type of\nstay, presence\/absence of pharmacist and medication at admission and\ndischarge were obtained for study patients. Variations in the number of\nmedicines (NoM), anticholinergic burden (ACB), and potentially\ninappropriate medication (PIMs), at admission and discharge, were\nassessed as outcome variables. Anticholinergic burden and PIMs were\nidentified using the Anticholinergic Cognitive Burden scale and the\nEU(7)-PIM List, respectively. One-sample t-tests were applied to compare\noutcome variables\u2019 mean values at admission and discharge. A 4-way ANOVA\nwas employed to test the association between background and outcome\nvariables. Partial Eta squared (\u03b72) was used to measure the effect size.\nResults. The 3 LTCFs assisted 1643 patients during the study period, of\nwhich 1366 were included in data analysis. Only one LTCF had pharmacy\nservices. All outcome variables showed a statistically significant\nincrease at discharge compared with admission. Pharmacist\u2019s presence was\nstatistically significant at improving the NoM (p&lt;0.001) and\nACB score (p&lt;0.001), while no statistically significant value\nwas reached on PIMs (p = 0.642). Small effect size values were reached\nfor pharmacist impact on the NoM and ACB score (\u03b72 = 0.021, \u03b72 = 0.011,\nrespectively). Conclusion. The present findings suggest that\npharmacists\u2019 presence positively impacts the use of medications\nimplicated in adverse health outcomes in LTC patients.<\/jats:p>","DOI":"10.22541\/au.168210367.79773996\/v1","type":"posted-content","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T19:01:27Z","timestamp":1682103687000},"source":"Crossref","is-referenced-by-count":1,"title":["Impact of a pharmacist\u2019s presence on medication usage in Long-Term Care Facilities: a retrospective cohort study"],"prefix":"10.22541","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6627-0714","authenticated-orcid":true,"given":"Jo\u00e3o","family":"Gon\u00e7alves","sequence":"first","affiliation":[{"name":"iMedULisboa"}]},{"given":"Mariana","family":"Requeijo","sequence":"additional","affiliation":[{"name":"Resid\u00eancias Montepio"}]},{"given":"Betsy","family":"Sleath","sequence":"additional","affiliation":[{"name":"The University of North Carolina at Chapel Hill Eshelman School of Pharmacy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8466-0484","authenticated-orcid":true,"given":"Afonso","family":"Cavaco","sequence":"additional","affiliation":[{"name":"iMed.ULisboa Research Institute for Medicines and Pharmaceutical Sciences"}]}],"member":"311","container-title":[],"original-title":[],"deposited":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T19:01:28Z","timestamp":1682103688000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.authorea.com\/users\/610164\/articles\/639200-impact-of-a-pharmacist-s-presence-on-medication-usage-in-long-term-care-facilities-a-retrospective-cohort-study?commit=4b76f7e624538fe3a5a1ac0411b66e8253f825c2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,21]]},"references-count":0,"URL":"https:\/\/doi.org\/10.22541\/au.168210367.79773996\/v1","relation":{},"subject":[],"published":{"date-parts":[[2023,4,21]]},"subtype":"preprint"}}