{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T05:50:10Z","timestamp":1791611410294,"version":"4.3.4"},"reference-count":30,"publisher":"The Japanese Society of Interventional Radiology","issue":"0","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,5]]},"DOI":"10.22575\/interventionalradiology.2025-0091","type":"journal-article","created":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T22:11:18Z","timestamp":1791151878000},"page":"e2025-0091-e2025-0091","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of the Peritoneovenous Shunt as Palliative Care for Patients with Advanced Cancer with Refractory Ascites: A Randomized Controlled Trial (JIVROSG-0803 Study)"],"prefix":"10.22575","volume":"11","author":[{"given":"Yasuaki","family":"Arai","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology, National Cancer Center Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miyuki","family":"Sone","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, National Cancer Center Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshito","family":"Takeuchi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Fukuchiyama City Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Sugawara","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, National Cancer Center Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Aramaki","sequence":"additional","affiliation":[{"name":"Division of Interventional Radiology, Shizuoka Cancer Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiro","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Radiology and IVR Center, Nara Medical University, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikio","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Ryugasaki Saiseikai Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Morita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Niigata Prefectural Central Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"9863","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Arai Y, Inaba Y, Sone M, et al. Phase I\/II study of transjugular transhepatic peritoneovenous venous shunt, a new procedure to manage refractory ascites in cancer patients: Japan Interventional Radiology in Oncology Study Group 0201. AJR Am J Roentgenol. 2011; 196: W621-W626.","DOI":"10.2214\/AJR.10.4716"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Ikegami T, Ishiki H, Kadono T, Ito T, Yokomichi N. Narrative review of malignant ascites: epidemiology, pathophysiology, assessment, and treatment. Ann Palliat Med. 2024; 13: 842-857.","DOI":"10.21037\/apm-23-554"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Sugawara S, Sone M, Arai Y, et al. Radiological insertion of Denver peritoneovenous shunts for malignant refractory ascites: a retrospective multicenter study (JIVROSG-0809). Cardiovasc Intervent Radiol. 2011; 34: 980-988.","DOI":"10.1007\/s00270-010-0057-y"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Becker G, Galandi D, Blum HE. Malignant ascites: systematic review and guideline for treatment. Eur J Cancer. 2006; 42: 589-597.","DOI":"10.1016\/j.ejca.2005.11.018"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Smith EM, Jayson GC. The current and future management of malignant ascites. Clin Oncol (R Coll Radiol). 2003; 15: 59-72.","DOI":"10.1053\/clon.2002.0135"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Saif MW, Siddiqui IA, Sohail MA. Management of ascites due to gastrointestinal malignancy. Ann Saudi Med. 2009; 29: 369-377.","DOI":"10.5144\/0256-4947.2009.369"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Sangisetty SL, Miner TJ. Malignant ascites: a review of prognostic factors, pathophysiology and therapeutic measures. World J Gastrointest Surg. 2012; 4: 87-95.","DOI":"10.4240\/wjgs.v4.i4.87"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Adam RA, Adam YG. Malignant ascites: past, present, and future. J Am Coll Surg. 2004; 198: 999-1011.","DOI":"10.1016\/j.jamcollsurg.2004.01.035"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Ayll\u00f3n MD, Ciria R, G\u00f3mez-Luque I, et al. Use of peritoneovenous shunt for the management of refractory ascites. Transplant Proc. 2019; 51: 41-43.","DOI":"10.1016\/j.transproceed.2018.04.089"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Bieligk SC, Calvo BF, Coit DG. Peritoneovenous shunting for nongynecologic malignant ascites. Cancer. 2001; 91: 1247-1255.","DOI":"10.1002\/1097-0142(20010401)91:7<1247::AID-CNCR1125>3.0.CO;2-W"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Bratby MJ, Hussain FF, Lopez AJ. Radiological insertion and management of peritoneovenous shunt. Cardiovasc Intervent Radiol. 2007; 30: 415-418.","DOI":"10.1007\/s00270-006-0213-6"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Gough IR, Balderson GA. Malignant ascites. A comparison of peritoneovenous shunting and nonoperative management. Cancer. 1993; 71: 2377-2382.","DOI":"10.1002\/1097-0142(19930401)71:7<2377::AID-CNCR2820710732>3.0.CO;2-H"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Mamada Y, Yoshida H, Taniai N, et al. Peritoneovenous shunts for palliation of malignant ascites. J Nippon Med Sch. 2007; 74: 355-358.","DOI":"10.1272\/jnms.74.355"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Martin LG. Percutaneous placement and management of peritoneovenous shunts. Semin Intervent Radiol. 2012; 29: 129-134.","DOI":"10.1055\/s-0032-1312574"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Qazi R, Savlov ED. Peritoneovenous shunt for palliation of malignant ascites. Cancer. 1982; 49: 600-602.","DOI":"10.1002\/1097-0142(19820201)49:3<600::AID-CNCR2820490333>3.0.CO;2-T"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Schumacher DL, Saclarides TJ, Staren ED. Peritoneovenous shunts for palliation of the patient with malignant ascites. Ann Surg Oncol. 1994; 1: 378-381.","DOI":"10.1007\/BF02303809"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Seike M, Maetani I, Sakai Y. Treatment of malignant ascites in patients with advanced cancer: peritoneovenous shunt versus paracentesis. J Gastroenterol Hepatol. 2007; 22: 2161-2166.","DOI":"10.1111\/j.1440-1746.2006.04793.x"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Siebert S, Helbling C, Wolff M, et al. Peritoneovenous shunting as palliative treatment in an infant with chylous ascites due to generalised congenital lymphangiectasia. Klin Padiatr. 2010; 222: 317-318.","DOI":"10.1055\/s-0030-1247588"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. S\u00f6derlund C. Denver peritoneovenous shunting for malignant or cirrhotic ascites. A prospective consecutive series. Scand J Gastroenterol. 1986; 21: 1161-1172.","DOI":"10.3109\/00365528608996438"},{"key":"20","unstructured":"20. Tueche SG, Pector JC. Peritoneovenous shunt in malignant ascites. The Bordet Institute experience from 1975-1998. Hepato-gastroenterology. 2000; 47: 1322-1324."},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. White MA, Agle SC, Padia RK, Zervos EE. Denver peritoneovenous shunts for the management of malignant ascites: a review of the literature in the post LeVeen Era. Am Surg. 2011; 77: 1070-1075.","DOI":"10.1177\/000313481107700830"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Won JY, Choi SY, Ko HK, et al. Percutaneous peritoneovenous shunt for treatment of refractory ascites. J Vasc Interv Radiol. 2008; 19: 1717-1722.","DOI":"10.1016\/j.jvir.2008.09.005"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Morita T, Tsunoda J, Inoue S, Chihara S. The Palliative Prognostic Index: a scoring system for survival prediction of terminally ill cancer patients. Support Care Cancer. 1999; 7: 128-133.","DOI":"10.1007\/s005200050242"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Aramaki T, Arai Y, Takeuchi Y, et al. A randomized, controlled trial of the efficacy of percutaneous transesophageal gastro-tubing (PTEG) as palliative care for patients with malignant bowel obstruction: the JIVROSG0805 trial. Support Care Cancer. 2020; 28: 2563-2569.","DOI":"10.1007\/s00520-019-05066-8"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Takeuchi Y, Arai Y, Sone M, et al. Evaluation of stent placement for vena cava syndrome: phase II trial and phase III randomized controlled trial. Support Care Cancer. 2019; 27: 1081-1088.","DOI":"10.1007\/s00520-018-4397-5"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Tsuchiya A, Ikeda S, Ikegami N, et al. Estimating an EQ-5D population value set: the case of Japan. Health Econ. 2002; 11: 341-353.","DOI":"10.1002\/hec.673"},{"key":"27","unstructured":"27. Fukuhara S, Suzukamo Y. Manual of the SF-8 Japanese version Research. Kyoto, Japan: Institute for Health Outcomes &amp; Process Evaluation Research (iHope International); 2004. p.154."},{"key":"28","unstructured":"28. Taniura T, Yamamoto T, Inoue K, et al. Role of peritoneovenous shunt therapy in end-of-life care of refractory malignant ascites cases. Nihon Shokakibyo Gakkai Zasshi. 2023; 120: 1003-1011. Japanese."},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Segawa T, Kato K, Kawashima K, Suzuki T, Ehara S. The influence of a peritoneovenous shunt for cirrhotic and malignant intractable ascites on renal function. Acta Radiol Open. 2018; 7: 2058460118764208.","DOI":"10.1177\/2058460118764208"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Zenda S, Arai Y, Sugawara S, et al. Protocol for a confirmatory trial of the effectiveness and safety of palliative arterial embolization for painful bone metastases. BMC Cancer. 2023; 23: 109.","DOI":"10.1186\/s12885-023-10538-6"}],"container-title":["Interventional Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/interventionalradiology\/11\/0\/11_2025-0091\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T05:13:49Z","timestamp":1791609229000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/interventionalradiology\/11\/0\/11_2025-0091\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,5]]},"references-count":30,"journal-issue":{"issue":"0","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.22575\/interventionalradiology.2025-0091","relation":{},"ISSN":["2432-0935"],"issn-type":[{"value":"2432-0935","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,5]]},"article-number":"2025-0091"}}