{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T12:40:25Z","timestamp":1685104825837},"reference-count":3,"publisher":"National Library of Serbia","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta chir iugo","ACTA CHIR IUG","ACTA CHIR IUGOSL"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>Introduction: Etiology of thrombosis in malignant diseases is multifactorial, and mechanisms that lead to thrombosis include release of the procoagulants from tumor cells (PC), factor related to bed rest, infections, as well as oncological therapy - chemotherapy, hormones, radiotherapy and surgical treatment. Thrombocytosis has frequently been found to be associated with various malignancies. Case report: 53 years old female patient hospitalized because of hypopharingeal cancer with metastasis in the left neck. Her state was complicated with deep leg vein thrombosis and pseudomonas infection. Persistent thrombocitosis in laboratory monitoring indicated more adequate diagnostic procedures, which led to discovering of Chorioidal Malignant Mellanoma as a second cancer. She was treated: Surgically, with antibiotics, with anticoagulants and radiotherapy. Patient was discharged from the hospital in good health condition, free of any other symptom of the malignant disease. Conclusion: Presence of thrombocytosis and idiopatic thrombosis can suggest occult malignancy. It would be prudent to further evaluate the relationship of trombotic events, trombocitosis and head and neck tumors. We suggest anticoagulants to prevent thromboembolic complications, affect the angiogenesis and prevent development of metastatic disease. It may lead to lower mortality rate.<\/jats:p>","DOI":"10.2298\/aci0503091d","type":"journal-article","created":{"date-parts":[[2008,11,28]],"date-time":"2008-11-28T15:05:29Z","timestamp":1227884729000},"page":"91-93","source":"Crossref","is-referenced-by-count":1,"title":["Patient with double cancer: Successfully treated"],"prefix":"10.2298","volume":"52","author":[{"given":"V.B.","family":"Djukic","sequence":"first","affiliation":[{"name":"Institute of Othorhynolaringology and maxillofacial surgery"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"A.","given":"Dragana","family":"Kastratovic","sequence":"additional","affiliation":[{"name":"Centre for Clinical Pharmacology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.P.","family":"Pendjer","sequence":"additional","affiliation":[{"name":"Institute of Othorhynolaringology and maxillofacial surgery"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"M.","given":"Branislava","family":"Majstorovic","sequence":"additional","affiliation":[{"name":"Centre for Clinical Pharmacology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lj.I.","family":"Nikolic","sequence":"additional","affiliation":[{"name":"Institute for gynecology and obstetrics, Laboratory of haematology and transfusiology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"V.","given":"Ivan","family":"Boricic","sequence":"additional","affiliation":[{"name":"Institute for pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.N.","family":"Vujicic","sequence":"additional","affiliation":[{"name":"Institute of Othorhynolaringology and maxillofacial surgery"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199909000-00001"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2004.01.022"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2003.10.039"}],"container-title":["Acta chirurgica Iugoslavica"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T12:06:19Z","timestamp":1685102779000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0354-950X0503091D"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":3,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.2298\/aci0503091d","relation":{},"ISSN":["0354-950X","2406-0887"],"issn-type":[{"value":"0354-950X","type":"print"},{"value":"2406-0887","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}