{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T04:03:41Z","timestamp":1685160221274},"reference-count":6,"publisher":"National Library of Serbia","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta chir iugo","ACTA CHIR IUG","ACTA CHIR IUGOSL"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>During the period 1995-2004 we treated 212 patients (pts) with brain tumors. There were 133 boys and 79 girls, aged from 2,5 yrs up to 18 yrs (Me=9,7 yrs). The majority of pts were in age group (4-16) yrs-179 pts. Supratentorial tumors were diagnosed in 118 pts vs. infratentorial 94 pts. Therapy involved surgery, postoperative radiotherapy with or without chemotherapy. Survival rates were calculated using Caplan-Meier method and differences between curves with log-rank test. During the follow-up period from 1 to 9 year (Me=3 yrs) 5-year disease free survival rate was 55,7%. 79 pts failed to therapy. There was no statistically significant difference in survival according to sex (p=0,123) and age (p=0,367). Pts with supratentorial tumors had statistically significant better survival (p=0,036). Pts with histologic type lowgrade astrocitomas had statistically significant better survival than malignant gliomas, ependymomas and PNET (p=0,0001). Surgery, postoperative radiotherapy and chemotherapy in selected cases are efficient therapeutic approach for pediatric brain tumors.<\/jats:p>","DOI":"10.2298\/aci0904019n","type":"journal-article","created":{"date-parts":[[2010,3,17]],"date-time":"2010-03-17T08:56:38Z","timestamp":1268816198000},"page":"19-24","source":"Crossref","is-referenced-by-count":1,"title":["Pediatric brain tumors: Diagnostic and treatment"],"prefix":"10.2298","volume":"56","author":[{"given":"M.R.","family":"Nikitovic","sequence":"first","affiliation":[{"name":"Institut za onkologiju i radiologiju Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.V.","family":"Golubicic","sequence":"additional","affiliation":[{"name":"Institut za onkologiju i radiologiju Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.D.","family":"Borojevic","sequence":"additional","affiliation":[{"name":"Institut za onkologiju i radiologiju Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.D.","family":"Pekmezovic","sequence":"additional","affiliation":[{"name":"Institut za epidemiologiju, Medicinski Fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.M.","family":"Grujicic","sequence":"additional","affiliation":[{"name":"Institut za neurohirurgiju, KC Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.S.","family":"Plesinac-Karapandzic","sequence":"additional","affiliation":[{"name":"Institut za onkologiju i radiologiju Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1080\/08880010902973533"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410290403"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(99)00015-8"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1177\/0883073809342491"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-911X(199812)31:6<506::AID-MPO7>"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.47.428"}],"container-title":["Acta chirurgica Iugoslavica"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T12:08:38Z","timestamp":1685102918000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0354-950X0904019N"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.2298\/aci0904019n","relation":{},"ISSN":["0354-950X","2406-0887"],"issn-type":[{"value":"0354-950X","type":"print"},{"value":"2406-0887","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}