{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T09:40:21Z","timestamp":1685353221382},"reference-count":9,"publisher":"National Library of Serbia","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med pregl","MED PREGLED"],"published-print":{"date-parts":[[2003]]},"abstract":"<jats:p>Introduction The aim of this study was to examine interconnections between changes in serum levels of biochemical parameters during pregnancy and sonographic parameters relevant for evaluation of early pregnancy. Material and methods We analyzed serum levels of human chorionic gonadotropin (HCG) estradiol (E2), progesterone (PRG) and prolactin (PRL) using ELISA method, in cases of complicated pregnancies with symptoms of imminent miscarriage, and in patients with uncomplicated pregnancies. We evaluated their impact on mean gestational sac diameter (MSD), crown-rump length (CRL), inner diameter of the vitelline sac (SV), trophoblast (Trf) thickness and embryonic heart rate (STP). All results were correlated using Pearson's test and regression Results Changes in biochemical parameters of pregnancy correlate significantly with dimensions of analyzed sonographic parameters. Discussion Levels of chorionic gonadotropin affect production of ovarian and placental steroidogenesis,. Interrelations were also discussed. Conclusion Changes in biochemical values of pregnancy hormones affect dimensions of analyzed sonographic parameters. During uncomplicated pregnancy, levels of chorionic gonadotropin, progesterone and estradiol affect mean gestation-sac diameter embryo length, depth of trophoblast invasion and formation and function of vitelline sac, and thus they alter the embryonic heart rate.<\/jats:p>","DOI":"10.2298\/mpns0302063m","type":"journal-article","created":{"date-parts":[[2006,7,21]],"date-time":"2006-07-21T09:15:44Z","timestamp":1153473344000},"page":"63-68","source":"Crossref","is-referenced-by-count":0,"title":["Values of biochemical and sonographic parameters in early pregnancy in women with a history of recurrent abortions"],"prefix":"10.2298","volume":"56","author":[{"given":"Anita","family":"Mitreski","sequence":"first","affiliation":[{"name":"Klini\u010dki centar, Novi Sad - Klinika za ginekologiju i aku\u0161erstvo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordana","family":"Radeka","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar, Novi Sad - Klinika za ginekologiju i aku\u0161erstvo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/12.12.2820"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3552(05)80092-6"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod43.5.898"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199811000-00001"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70618-5"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70409-5"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s004040000111"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1210\/jc.84.1.291"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1042\/BST0290052"}],"container-title":["Medicinski pregled","Medical review"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T09:18:03Z","timestamp":1685351883000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0025-81050302063M"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"references-count":9,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2003]]}},"URL":"https:\/\/doi.org\/10.2298\/mpns0302063m","relation":{},"ISSN":["0025-8105","1820-7383"],"issn-type":[{"value":"0025-8105","type":"print"},{"value":"1820-7383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003]]}}}