{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T04:07:33Z","timestamp":1685419653447},"reference-count":0,"publisher":"National Library of Serbia","issue":"9-10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med pregl","MED PREGLED"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Introduction. Neuropathic pain, or pain associated with disease or injury to\n   the peripheral or central nervous system, is a common symptom of a\n   heterogeneous group of conditions, including diabetic neuropathy, trigeminal\n   neuralgia, postherpetic neuralgia and spinal cord injury. Chronic neuropathic\n   pain should not be thought of as a symptom. It should truly be thought of as\n   a disease with a very complicated pathophysiology. Pathophysiology. The\n   mechanisms involved in neuropathic pain are complex and involve both\n   peripheral and central pathophysiologic phenomenon. The underlying\n   dysfunction may involve deafferentation within the peripheral nervous system\n   (e.g. neuropathy), deafferentation within the central nervous system (e.g.\n   post-thalamic stroke) or an imbalance between the two (e.g. phantom limb\n   pain). Clinical characteristics. Neuropathic pain is non-nociceptive, in\n   contrast to acute nociceptive pain, and it can be described as ?burning?,\n   ?electric?, ?tingling?, and ?shooting? in nature. Treatment. Rational\n   polypharmacy is often necessary and actually it is almost always the rule. It\n   would be an exception if a patient was completely satisfied with his\n   treatment. Treatment goals should include understanding that our patients may\n   need to be titrated and managed with more than one agent and one type of\n   treatment. There should be the balance of safety, efficacy, and tolerability.\n   Conclusion. There are many new agents and new applications of the existing\n   agents being currently studied which will most certainly lead to even more\n   improved ways of managing this very complicated set of disorders.<\/jats:p>","DOI":"10.2298\/mpns1110443c","type":"journal-article","created":{"date-parts":[[2011,11,17]],"date-time":"2011-11-17T16:01:58Z","timestamp":1321545718000},"page":"443-447","source":"Crossref","is-referenced-by-count":0,"title":["Contemporary treatment neuropathic pain"],"prefix":"10.2298","volume":"64","author":[{"given":"Milan","family":"Cvijanovic","sequence":"first","affiliation":[{"name":"Klini\u010dki centar Vojvodine, Klinika za neurologiju, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svetlana","family":"Simic","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Vojvodine, Klinika za neurologiju, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofija","family":"Banic-Horvat","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Vojvodine, Klinika za neurologiju, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zita","family":"Jovin","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Vojvodine, Klinika za neurologiju, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petar","family":"Slankamenac","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Vojvodine, Klinika za neurologiju, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miroslav","family":"Ilin","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Vojvodine, Klinika za neurologiju, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Medicinski pregled","Medical review"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T09:22:59Z","timestamp":1685352179000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0025-81051110443C"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":0,"journal-issue":{"issue":"9-10","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.2298\/mpns1110443c","relation":{},"ISSN":["0025-8105","1820-7383"],"issn-type":[{"value":"0025-8105","type":"print"},{"value":"1820-7383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}