{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T04:09:07Z","timestamp":1685419747926},"reference-count":0,"publisher":"National Library of Serbia","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med pregl","MED PREGLED"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Introduction. Schizophrenia represents the most severe mental disorder. The\n   aim of this study was to determine the frequency of disease in the first line\n   relatives of patients suffering from schizophrenia related to gender\n   differences and various subtypes. Material and Methods. The study included\n   453 subjects (121 patients suffering from schizophrenia - 52.1% males and\n   47.9% females and 332 first line relatives of the patients - 47.2% males and\n   52.7% females during a five year period, mostly in the region of Sarajevo.\n   Results. According to the analysis of disease frequency related to the\n   kinship, the disease developed more frequently in mothers (8.3%) and sisters\n   (7.8%) than in fathers (6.9) and brothers (7.1%) of the patients suffering\n   from paranoid schizophrenia. In the group of disorganized schizophrenia, only\n   mothers were found (4.2%), whereas the statistical difference in the group of\n   affected brothers and sisters was significant, the percentage being 9.7% and\n   15.3%, respectively. There was a statistically significant difference in\n   gender (p&lt;0.05) between the group of parents and siblings regarding the\n   frequency of schizophrenia. Discussion. The proof of participation of genetic\n   factors in etiology supports the assumption on genetic nature of familial\n   aggregation of schizophrenia. Our results completely match those of studies\n   which analyzed the frequency of disease regarding inheritance (gender\n   distribution and various subtypes). Conclusion. Investigation points to the\n   common epidemiological criteria regarding the frequency of schizophrenic\n   psychosis. Genetic predisposition could be also a demonstrator of the disease\n   course and outcome, which should enable better understanding of the etiology\n   of this disease.<\/jats:p>","DOI":"10.2298\/mpns1302019s","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T09:33:18Z","timestamp":1361266398000},"page":"19-23","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of disease frequency in the first line relatives of patients suffering from schizophrenia related to gender and diagnostic categories"],"prefix":"10.2298","volume":"66","author":[{"given":"Gorana","family":"Sulejmanpasic-Arslanagic","sequence":"first","affiliation":[{"name":"Univerzitet Sarajevo,Klini\u010dki centar Psihijatrijska klinika, Sarajevo, Bosna i Hercegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Medicinski pregled","Medical review"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T09:23:55Z","timestamp":1685352235000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0025-81051302019S"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":0,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.2298\/mpns1302019s","relation":{},"ISSN":["0025-8105","1820-7383"],"issn-type":[{"value":"0025-8105","type":"print"},{"value":"1820-7383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}