{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T16:16:48Z","timestamp":1780330608064,"version":"3.54.1"},"reference-count":0,"publisher":"National Library of Serbia","issue":"11-12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med pregl","MED PREGLED"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Introduction. This research has been aimed at determining whether incomplete\n   Circle of Willis in patients with significant extracranial carotid stenosis\n   is associated with a higher incidence of neurological symptomatology and\/or\n   ischemic cerebral lesions. Material and Methods. The research was conducted\n   as a prospective study which comprised 211 patients who underwent surgical\n   treatment of extracranial carotid disease at the Department of Vascular\n   Surgery in Novi Sad and 102 patients in the control group. Each patient\n   underwent preoperative magnetic resonance imaging and magnetic resonance\n   angiography with visualization of cerebral parenchyma, extracranial and\n   intracranial cerebral circulation. Assessment of Circle of Willis morphology\n   was performed by 3D time-of-flight magnetic resonance angiogram sequence\n   analysis. The patients were divided into two groups: group I - the patients\n   with complete Circle of Willis and group II - the patients with incomplete\n   Circle of Willis i.e. with the disruption of anterior and\/or ipsilateral\n   posterior circulation - regarding the side of significant carotid stenosis.\n   Results. Out of 211 patients who were operated during a two-year period, 133\n   had the complete Circle of Willis, while 78 patients had the incomplete\n   Circle of Willis. Out of 111 patients with symptomatic carotid disease or\n   silent cerebral infarction, 52.5% (58) had the complete Circle of Willis\n   and 47.5% (53) had the incomplete Circle of Willis. It was shown to be\n   statistically different (P = 0.0146) in relation with the asymptomatic\n   group of patients (100), where the frequency of the complete Circle of\n   Willis was 75% (75) while the insufficiency of anterior or ipsilateral\n   posterior collateralization was found in 25% (25). In the control group\n   there were significantly fewer cases of developed collateral flow and the\n   complete Circle of Willis (41%) compared to the operated patients with\n   extracranial carotid stenosis (63%) (P = 0.0003). Conclusion. Incompleteness\n   of Circle of Willis is associated with more frequent occurrence of\n   neurological symptomatology or ischemic lesions of brain parenchyma in\n   operated patients with significant extracranial carotid stenosis. The\n   control group without extracranial carotid stenosis had less developed\n   collaterals of Circle of Willis compared to extracranial carotid patients.<\/jats:p>","DOI":"10.2298\/mpns1612351m","type":"journal-article","created":{"date-parts":[[2017,1,23]],"date-time":"2017-01-23T13:19:44Z","timestamp":1485177584000},"page":"351-355","source":"Crossref","is-referenced-by-count":6,"title":["Completeness of Circle of Willis in asymptomatic and symptomatic extracranial carotid disease"],"prefix":"10.2298","volume":"69","author":[{"given":"Vladimir","family":"Manojlovic","sequence":"first","affiliation":[{"name":"Clinical Center of Vojvodina, Clinic for Vascular Surgery, Novi Sad"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladan","family":"Popovic","sequence":"additional","affiliation":[{"name":"Clinical Center of Vojvodina, Clinic for Vascular Surgery, Novi Sad"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dragan","family":"Nikolic","sequence":"additional","affiliation":[{"name":"Clinical Center of Vojvodina, Clinic for Vascular Surgery, Novi Sad"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djordje","family":"Milosevic","sequence":"additional","affiliation":[{"name":"Clinical Center of Vojvodina, Clinic for Vascular Surgery, Novi Sad"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janko","family":"Pasternak","sequence":"additional","affiliation":[{"name":"Clinical Center of Vojvodina, Clinic for Vascular Surgery, Novi Sad"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nebojsa","family":"Budakov","sequence":"additional","affiliation":[{"name":"Clinical Center of Vojvodina, Clinic for Vascular Surgery, Novi Sad"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1078","container-title":["Medicinski pregled","Medical review"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T09:25:37Z","timestamp":1685352337000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0025-81051612351M"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":0,"journal-issue":{"issue":"11-12","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.2298\/mpns1612351m","relation":{},"ISSN":["0025-8105","1820-7383"],"issn-type":[{"value":"0025-8105","type":"print"},{"value":"1820-7383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}