{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:58:06Z","timestamp":1747209486447,"version":"3.40.5"},"reference-count":0,"publisher":"National Library of Serbia","issue":"Suppl. 4","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>INTRODUCTION. Adult polycystic kidney disease (APKD) is the most common\n   hereditary kidney disease in humans. The course of the disease is accompanied\n   by numerous complications. OBJECTIVE The aim was to assess the prevalence,\n   clinical course and outcome of adult dominant polycystic kidney disease\n   (ADPKD) patients on renal replacement therapy. METHOD. Medical data on 700\n   haemodialyzed (HD) and 500 transplanted patients treated in 10 Serbian\n   centres from 1996 to 2000 were retrospectively analyzed. While ADPKD patients\n   accounted for 13% of HD patients in Serbia in 2000, in the period between\n   1996 and 2000, the percent of patients with ADPKD in the population of\n   patients starting HD in 8 examined centres changed from 13.5% to 6.9%.\n   RESULTS. The total number of 180 ADPKD patients on HD was analyzed (96 males;\n   aged 55 years at HD onset). Their HD lasted between 1 and 22 years: males\n   started HD 1.3 years earlier and spent on HD 1.1 years less than females. In\n   53% of HD patients one or more family members had ADPKD but the cause of\n   death was unknown for many family members. Hypertension was present in 75% of\n   ADPKD patients, anaemia in 37% and other organ involvement (usually liver)\n   was found in 53 patients. Fifty patients experienced AV fistula thrombosis\n   and a vascular prosthesis had to be used in 9 of them. A hundred and two HD\n   patients died (aged between 38 and 78 years, on HD for 5.3 years). The causes\n   of death were stroke (19.6%), cardiovascular diseases (29%), infections,\n   while 5% of patients died with the picture of acute abdomen. Among 500\n   transplanted patients, there were 20 patients with ADPKD (11 males, ages\n   between 35 and 56 years at the time of transplantation) and 14 of them\n   received graft from cadaver donor. Uni- or bilateral nephrectomy was done in\n   4 patients in the pretransplant preparation, and in another two early after\n   transplantation due to urinary infection. Three patients restarted HD in the\n   first 3 months after transplantation due to acute tubular necrosis and 10\n   patients died 56.5 months after the transplantation. The known causes of\n   death were cardiovascular disease (3 patients), severe gastrointestinal\n   bleeding (2 patients), infection (2 patients) and cancer (2 patients).\n   CONCLUSION. The obtained results showed that it was possible to provide a\n   favourable outcome of patients with APBB on renal replacement therapy in\n   spite of numerous complications.<\/jats:p>","DOI":"10.2298\/sarh08s4287l","type":"journal-article","created":{"date-parts":[[2015,8,6]],"date-time":"2015-08-06T11:13:58Z","timestamp":1438859638000},"page":"287-293","source":"Crossref","is-referenced-by-count":0,"title":["Renal replacement therapy in adult dominant polycystic kidney disease - multicentre study"],"prefix":"10.2298","volume":"136","author":[{"given":"Visnja","family":"Lezaic","sequence":"first","affiliation":[{"name":"Clinical Centre of Serbia, Institute of Urology and Nephrology, Department of Nephrology, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Ostric","sequence":"additional","affiliation":[{"name":"Clinical Centre of Serbia, Institute of Urology and Nephrology, Department of Nephrology, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4242-1132","authenticated-orcid":false,"given":"Gordana","family":"Popovic","sequence":"additional","affiliation":[{"name":"Zvezdara Clinical Centre, Unit for Haemodialysis, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milja","family":"Vukoje","sequence":"additional","affiliation":[{"name":"Medical Centre, Unit for Dialysis, Zrenjanin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Branislava","family":"Dragoljic","sequence":"additional","affiliation":[{"name":"Medical Centre \u201cKosta Sredojevi\u0107 \u0160ljuka\u201d, Unit for Dialysis, Kikinda"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevena","family":"Kostic","sequence":"additional","affiliation":[{"name":"Medical Centre \u201cStudenica\u201d, Unit for Dialysis, Kraljevo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Stojanovic","sequence":"additional","affiliation":[{"name":"Internal Medicine Hospital, Unit for Haemodialysis, Mladenovac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milorad","family":"Labudovic","sequence":"additional","affiliation":[{"name":"Health Centre, Unit for Haemodialysis, Obrenovac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milan","family":"Mandic","sequence":"additional","affiliation":[{"name":"Medical Centre \u201cDr Radivoj Simonovi\u0107\u201d, Unit for Haemodialysis, Sombor"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verica","family":"Djordjevic","sequence":"additional","affiliation":[{"name":"General Hospital \u201cStefan Visoki\u201d, Unit for Dialysis, Smederevska Palanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jovan","family":"Bakovic","sequence":"additional","affiliation":[{"name":"General Hospital, Medical Centre, Unit for Haemodialysis, \u010ca\u010dak"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:27:15Z","timestamp":1685356035000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-817908287L"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":0,"journal-issue":{"issue":"Suppl. 4","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh08s4287l","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"type":"print","value":"0370-8179"},{"type":"electronic","value":"2406-0895"}],"subject":[],"published":{"date-parts":[[2008]]}}}