{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:56:08Z","timestamp":1747209368916,"version":"3.40.5"},"reference-count":10,"publisher":"National Library of Serbia","issue":"3-4","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Introduction. About one half of the first gout attacks occur in the first\n   metatarsophalangeal joint (MTPJ1); in the disease course this joint is\n   practically inevitably affected. Radiographic evidence of bone erosions is\n   the indication for hypouricaemic therapy in order to prevent joint\n   destruction and nephropathy. Advantages of ultrasonography (US) comparing to\n   conventional x-ray findings in depicting early bone erosions in various\n   inflammatory arthropathies have been demonstrated by several studies.\n   Objective. The aims of this study were to compare US and x-ray findings in\n   the detection of MTPJ1 erosions in patients with gout, to correlate\n   sonographic and clinical features, and to detect possible characteristic\n   sonographic features of gout. Methods. Thirty patients (60 MTPJ1) with\n   primary gout (ACR) and 10 age-matched control subjects (20 MTPJ1) with\n   different inflammatory arthropathies were clinically evaluated. Standard\n   dorsiplantar weight bearing and lateral weight bearing x-ray views of both\n   feet were taken. US was performed and interpreted by an independent\n   sonographer on the presence of bone erosions, synovial fluid, synovial\n   hypertrophy, Doppler signal and hyperechoic spots. Statistical analysis was\n   performed (Spearman and Pearson correlation coefficient, Wilcoxon and ?2\n   test.) Results. Twenty-four studied MTPJ1 had evidence of erosions, 17 only\n   on US and seven both on x-ray and on US (Z=-4.123; p=0.000). US findings\n   showed that hyperechoic spots were the most prominent feature of gouty MTPJ1\n   (?2=40.909; p=0.000), followed by erosions and synovial fluid presentation.\n   Conclusion. US of MTPJ1 in gout discovers significantly more erosions than\n   x-ray, which may have therapeutic implications. The evidence of hyperechoic\n   spots (surrogate crystals) of the different size, number and orientation is a\n   major sonographic feature of the MTPJ1 in gout, which may be of importance in\n   the diagnosis of certain cases (low serum urate, unavailable synovial fluid\n   or the urate crystals absence).<\/jats:p>","DOI":"10.2298\/sarh1104161r","type":"journal-article","created":{"date-parts":[[2011,6,14]],"date-time":"2011-06-14T21:29:45Z","timestamp":1308086985000},"page":"161-164","source":"Crossref","is-referenced-by-count":2,"title":["Ultrasonography of the first metatarsophalangeal joint in gout"],"prefix":"10.2298","volume":"139","author":[{"given":"Marija","family":"Radak-Perovic","sequence":"first","affiliation":[{"name":"Institut za reumatologiju, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktorija","family":"Savic","sequence":"additional","affiliation":[{"name":"Institut za reumatologiju, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3225-3793","authenticated-orcid":false,"given":"Sanja","family":"Milutinovic","sequence":"additional","affiliation":[{"name":"Institut za reumatologiju, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7123-140X","authenticated-orcid":false,"given":"Mirjana","family":"Zlatkovic-Svenda","sequence":"additional","affiliation":[{"name":"Institut za reumatologiju, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200105000-00015"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200012)43:12<2762::AID-ANR16>3.0"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1186\/ar1904"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/37.11.1152"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2006.062802"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/01.bor.0000209430.59226.0f"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.024109"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh214"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.1.52"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/art.20935"}],"container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:29:50Z","timestamp":1685356190000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791104161R"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":10,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1104161r","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"type":"print","value":"0370-8179"},{"type":"electronic","value":"2406-0895"}],"subject":[],"published":{"date-parts":[[2011]]}}}