{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:56:08Z","timestamp":1747209368928,"version":"3.40.5"},"reference-count":14,"publisher":"National Library of Serbia","issue":"3-4","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Introduction. Idiopathic ulcerative colitis (IUC) represents a rare disease\n   of childhood. It usually occurs at age over 10 years, and below that\n   exceptionally rarely. Objective. The aim of the paper was to analyze the\n   clinical signs, symptoms and therapeutic procedures in children with IUC.\n   Methods. The aims of the paper were based on a sample of 17 children (11 male\n   and 6 female, mean age 11.90?3.50 years; range 3.8-17.5 years) with IUC. The\n   disease diagnosis was based on characteristic endoscopic and\n   pathohistological findings. Results. The basic signs of the disease involved\n   chronic mucosal haemorrhagic diarrhoea which was confirmed in 16 of 17\n   patients, with body weight deficiency (10), recurrent abdominal pain (6),\n   fever (5), slowed-down maturation (5), marked anorexia (4), and tenesmus (3).\n   Two patients had recurrent aphthous stomatitis, 2 anal fissures, 2\n   arthralgia, one autoimmune hepatitis and one pyoderma gangrenosum. None of\n   the children had longitudinal growth retardation. Elevated sedimentation rate\n   and C-reactive protein in blood were registered in 11, sideropenia in 10,\n   anaemia in 6 and hypoalbuminemia in 3 patients. The remission of\n   proctosigmoiditis and left-sided colitis was achieved with aminosalicylates,\n   and of pancolitis with the combination of aminosalicylates and\n   glucocorticoids, except in cases of steroid-dependent colitis, which\n   additionally required azathioprine. Conclusion. The main signs of IUC in\n   children are chronic mucous haemorrhagic diarrhoea, body weight loss and\n   sideropenic anaemia, while the basic therapy consists of aminosalicylates,\n   and in more severe cases of the disease the initial use of glucocorticoids\n   and later azathioprine.<\/jats:p>","DOI":"10.2298\/sarh1104170l","type":"journal-article","created":{"date-parts":[[2011,6,14]],"date-time":"2011-06-14T21:29:45Z","timestamp":1308086985000},"page":"170-173","source":"Crossref","is-referenced-by-count":1,"title":["Clinical characteristics of idiopathic ulcerative colitis in children"],"prefix":"10.2298","volume":"139","author":[{"given":"Zoran","family":"Lekovic","sequence":"first","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nedeljko","family":"Radlovic","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd + Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radivoj","family":"Brdar","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd + Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biljana","family":"Vuletic","sequence":"additional","affiliation":[{"name":"Pedijatrijska klinika, Klini\u010dki centar, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nenad","family":"Janic","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd + Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragana","family":"Ristic","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zorica","family":"Stojsic","sequence":"additional","affiliation":[{"name":"Institut za patologiju, Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Radlovic","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8424-4704","authenticated-orcid":false,"given":"Dusica","family":"Simic","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd + Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0609-9916","authenticated-orcid":false,"given":"Dejan","family":"Nikolic","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3164\/jcbn.09-77"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.05785.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2005.080481"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1136\/gut.25.2.188"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1159\/000016891"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199101103240203"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199803000-00013"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/gut.42.2.188"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-03-0672"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2009.06.001"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-12-195651"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199406303302601"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199901000-00013"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(98)70251-3"}],"container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:29:51Z","timestamp":1685356191000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791104170L"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":14,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1104170l","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"type":"print","value":"0370-8179"},{"type":"electronic","value":"2406-0895"}],"subject":[],"published":{"date-parts":[[2011]]}}}