{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T04:07:10Z","timestamp":1685419630363},"reference-count":0,"publisher":"National Library of Serbia","issue":"9-10","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Introduction. For the difference from poorly differentiated, well\n   differentiated endocrine carcinomas of the pancreas are the tumours in whom\n   with aggressive surgery and chemotherapy fair results can be achieved.\n   Objective. The aim of the study was to point out the importance of such\n   treatment. Methods. Over a 6-year period eight patients (seven female and one\n   male) of average age 51 years (ranging from 23 to 71 years) were operated on\n   for well differentiated endocrine carcinoma: six of the head and two of the\n   tail of the pancreas. There were two functional and six nonfunctional\n   tumours. Pain in the upper part of the abdomen in seven, mild loss in weight\n   in two, strong heartburn in two, obstructive jaundice in three, diarrhoea in\n   one, sudden massive bleeding from gastric varicosities due to prehepatic\n   portal hypertension caused by pancreatic head tumour in one, and bruise in\n   one patient were registered preoperatively. US and CT in all, angiography in\n   one, octreoscan in two and PET scan in one patient were performed. Whipple?s\n   procedure was performed in six and distal pancreatectomy in two patients, as\n   well as systemic lymphadenectomy in all and excision of liver secondary\n   tumours in two patients. In the patient with massive gastric bleeding a total\n   gastrectomy was performed first, followed by Whipple?s procedure a month\n   later. Results. R0 resection was achieved in all patients. Lymph nodes\n   metastases were found in six patients. Six patients were given chemotherapy.\n   One patient died 3 years after surgery, seven are still alive, on average 2.5\n   years. A local recurrence after distal pancreatectomy that occurred 5 years\n   after surgery was successfully reresected and the patient is on\n   peptide-receptor radiotherapy. In other six patients there were no local\n   recurence or distant metastases. Conclusion. With aggressive surgery and\n   chemotherapy fair results can be achieved in well differentiated endocrine\n   carcinomas of the pancreas.<\/jats:p>","DOI":"10.2298\/sarh1110625c","type":"journal-article","created":{"date-parts":[[2011,11,8]],"date-time":"2011-11-08T09:09:52Z","timestamp":1320743392000},"page":"625-630","source":"Crossref","is-referenced-by-count":0,"title":["Well differentiated endocrine carcinomas of the pancreas"],"prefix":"10.2298","volume":"139","author":[{"given":"Radoje","family":"Colovic","sequence":"first","affiliation":[{"name":"Klinika za digestivnu hirurgiju, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikica","family":"Grubor","sequence":"additional","affiliation":[{"name":"Klinika za digestivnu hirurgiju, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjan","family":"Micev","sequence":"additional","affiliation":[{"name":"Klinika za digestivnu hirurgiju, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Dugalic","sequence":"additional","affiliation":[{"name":"Klinika za digestivnu hirurgiju, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dejan","family":"Stojakov","sequence":"additional","affiliation":[{"name":"Klinika za digestivnu hirurgiju, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stojan","family":"Latincic","sequence":"additional","affiliation":[{"name":"Klinika za digestivnu hirurgiju, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasa","family":"Colovic","sequence":"additional","affiliation":[{"name":"Klinika za hematologiju, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miodrag","family":"Jovanovic","sequence":"additional","affiliation":[{"name":"Klinika za digestivnu hirurgiju, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vesna","family":"Karapandzic","sequence":"additional","affiliation":[{"name":"Klinika za digestivnu hirurgiju, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:30:36Z","timestamp":1685356236000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791110625C"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":0,"journal-issue":{"issue":"9-10","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1110625c","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"value":"0370-8179","type":"print"},{"value":"2406-0895","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}