{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T11:44:34Z","timestamp":1769600674061,"version":"3.49.0"},"reference-count":0,"publisher":"National Library of Serbia","issue":"5-6","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Introduction. West Syndrome (WS) is age-related epileptic encephalopathy\n   characterised by a triad of symptoms: specific seizure type, pathognomonic\n   electroencephalographic (EEG) pattern - hypsarrhythmia and delay and\/or\n   regression in psychomotor development (PMD). Aetiologically, it occurs in\n   three forms: symptomatic, cryptogenic and idiopathic. Objective. Estimation\n   of PMD in children with WS according to aetiology. Methods. The observed\n   group consisted of 65 children. Age range was between 6 and 30 months. The\n   patients were divided into three groups according to aetiology. All patients\n   underwent psychological examination with Brunet-Lesine test, as well as PMD\n   evaluation based on achieved developmental milestones for the corresponding\n   age. Results. Statistically significant better values in the Human\n   Developmental Index (HDI) had patients with idiopathic compared to other\n   forms of WS, at testing after 12 months (93.0?8.1 vs. 46.8?6.1 vs. 45.6?3.8),\n   as well as after 24 months (93.9?7.7 vs. 51.9?5.5 vs. 50.9?4.4). The best\n   values of HDI after 24 months had patients with improvement in PMD with the\n   average of 66.2?4.4, which was statistically significant compared to those\n   with unchanged PMD (41.5?5.3) and with further regression in PMD (28.3?4.4).\n   Significant correlation was obtained between PMD after 12 and 24 months\n   (r=0.477), as well as a considerable improvement in HDI from the 12th to 24th\n   month (49.4?4.0 vs. 53.7?3.9). Conclusion. The patients with idiopathic WS\n   accomplished the best PMD. Improvement in PMD after 12 and 24 months of\n   treatment was associated with improved HDI. Improvement in PMD was observed\n   in all patients after 2 years of follow-up.<\/jats:p>","DOI":"10.2298\/sarh1206278n","type":"journal-article","created":{"date-parts":[[2012,7,18]],"date-time":"2012-07-18T06:30:58Z","timestamp":1342593058000},"page":"278-284","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of psycho-motor development in children with West syndrome"],"prefix":"10.2298","volume":"140","author":[{"given":"Dimitrije","family":"Nikolic","sequence":"first","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd + Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petar","family":"Ivanovski","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd + Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragana","family":"Bogicevic","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd + Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikola","family":"Dimitrijevic","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5772-4355","authenticated-orcid":false,"given":"Ivan","family":"Milovanovic","sequence":"additional","affiliation":[{"name":"Institut za patolo\u0161ku fiziologiju, Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selena","family":"Puric","sequence":"additional","affiliation":[{"name":"Univerzitetska de\u010dja klinika, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jovanka","family":"Delic","sequence":"additional","affiliation":[{"name":"Medicinski fakultet, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5356-8706","authenticated-orcid":false,"given":"Nevena","family":"Mihailovic-Stanojevic","sequence":"additional","affiliation":[{"name":"Institut za medicinska istra\u017eivanja, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:31:56Z","timestamp":1685356316000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791206278N"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":0,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1206278n","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"value":"0370-8179","type":"print"},{"value":"2406-0895","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}