{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T04:08:18Z","timestamp":1685419698727},"reference-count":0,"publisher":"National Library of Serbia","issue":"5-6","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Introduction. Chronic kidney disease (CKD) is a significant cause of\n   morbidity and mortality in paediatric population. Objective. The aim of the\n   study was analysis of aetiology, staging and associated complications of CKD\n   at the time of diagnosis. Methods. Data of 97 patients (56 boys) of average\n   age 7.8?5.8 years, referred for the first time to the Institute for Mother\n   and Child Healthcare ?Dr Vukan Cupic?, Belgrade in the period 1998- 2009, due\n   to CKD, stage 2-5, were analysed. In each patient illness history was\n   obtained, and physical examination, laboratory, X-ray and other\n   investigations were performed according to the indications. CKD was\n   classified according to the glomerular filtration rate into four grades: 2 -\n   mild (60-90 ml\/min\/1.73 m2); 3 - moderate (30-60 ml\/min\/1.73 m2); 4 -\n   advanced (15-30 ml\/ min\/1.73 m2); and 5 - terminal (&lt;15 ml\/min\/1.73 m2).\n   Results. The most frequent causes of CKD were congenital anomalies of the\n   kidney and urinary tract (43.3%), followed by glomerular diseases (17.5%),\n   hereditary kidney diseases (16.5%), metabolic diseases (7.2%) and other\n   causes (15.5%). Mild CKD was found in 29.8%, moderate in 28.9%, advanced in\n   22.7%, and terminal in 18.6% children. Among patients with CKD stage 4 and 5,\n   75% of patients presented with acute renal failure, while 25% had earlier\n   detected CKD (stage 1), but were not under regular follow-up. Associated\n   complications included metabolic acidosis (63%), anaemia (60%), hypertension\n   (42.3%), short stature (25.8%), renal osteodystrophy (13.4%) and\n   cardiovascular diseases (7.2%). Conclusion. Congenital anomalies of the\n   kidney and urinary tract are the leading cause of CKD in paediatric\n   population. A significant proportion (41.3%) of patients had advanced and\n   terminal CKD. In most patients CKD was diagnosed late and with associated\n   complications.<\/jats:p>","DOI":"10.2298\/sarh1206313p","type":"journal-article","created":{"date-parts":[[2012,7,18]],"date-time":"2012-07-18T06:30:58Z","timestamp":1342593058000},"page":"313-320","source":"Crossref","is-referenced-by-count":1,"title":["Chronic kidney disease during a 12-year period at tertiary health institution"],"prefix":"10.2298","volume":"140","author":[{"given":"Aleksandra","family":"Paripovic","sequence":"first","affiliation":[{"name":"Institut za zdravstvenu za\u0161titu majke i deteta Srbije \u201eDr Vukan \u010cupi\u0107\u201d, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasa","family":"Stajic","sequence":"additional","affiliation":[{"name":"Institut za zdravstvenu za\u0161titu majke i deteta Srbije \u201eDr Vukan \u010cupi\u0107\u201d, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jovana","family":"Putnik","sequence":"additional","affiliation":[{"name":"Institut za zdravstvenu za\u0161titu majke i deteta Srbije \u201eDr Vukan \u010cupi\u0107\u201d, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radovan","family":"Bogdanovic","sequence":"additional","affiliation":[{"name":"Institut za zdravstvenu za\u0161titu majke i deteta Srbije \u201eDr Vukan \u010cupi\u0107\u201d, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:32:00Z","timestamp":1685356320000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791206313P"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":0,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1206313p","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"value":"0370-8179","type":"print"},{"value":"2406-0895","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}