{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:56:18Z","timestamp":1747209378847,"version":"3.40.5"},"reference-count":0,"publisher":"National Library of Serbia","issue":"9-10","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Introduction. Gestational diabetes mellitus (GDM) is defined as any degree of\n   glucose intolerance with onset or first recognition during pregnancy. The\n   diagnosis of GDM is made by performing the oral glucose tolerance test (OGTT)\n   in women with risk factors, usually during 24th to 28th week of gestation.\n   The most common used insulin therapy regime is a conventional intensive\n   insulin therapy with four daily doses. Objective. The aim of our study was to\n   determine the changes in parameters of glycoregulation in GDM patients with\n   different approach to the introduction of insulin therapy. Methods. Study\n   group consisted of 50 pregnant women divided into two groups depending on the\n   parameters of glycoregulation (glycemic profile and HbA1). Group 1 consisted\n   of pregnant women initially treated with diet only and then, according to\n   glycemic profile and HbA1 profile, in the next few weeks with insulin\n   therapy. Group 2 were pregnant women who were treated with insulin therapy\n   immediately after GDM diagnosis. Results. There was a statistically\n   significant difference in mean glycemia values in the 60th and 120th minute\n   between the two groups (p=0.001). There was a difference in mean value of\n   fasting blood and postprandial glucose between the two groups; it was higher\n   in Group 2. There was a statistically significant difference between the two\n   groups in HbA1c value at the beginning (5.1?0.4% vs. 5.42?0.43%, p=0.005) and\n   at the end of therapy (4.87?0.29% vs. 5.1?0.39 %, p=0.018). Conclusion.\n   Satisfactory glycoregulation was achieved in both studied groups.<\/jats:p>","DOI":"10.2298\/sarh1210583m","type":"journal-article","created":{"date-parts":[[2012,11,26]],"date-time":"2012-11-26T08:53:05Z","timestamp":1353919985000},"page":"583-588","source":"Crossref","is-referenced-by-count":0,"title":["Changes in parameters of glycoregulation in gestational diabetes mellitus patients with different approach to insulin therapy introduction"],"prefix":"10.2298","volume":"140","author":[{"given":"Violeta","family":"Mladenovic","sequence":"first","affiliation":[{"name":"Centar za endokrinologiju, dijabetes i bolesti metabolizma, Interna klinika, Klini\u010dki centar, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandar","family":"Djukic","sequence":"additional","affiliation":[{"name":"Centar za endokrinologiju, dijabetes i bolesti metabolizma, Interna klinika, Klini\u010dki centar, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1528-9305","authenticated-orcid":false,"given":"Mirjana","family":"Varjacic","sequence":"additional","affiliation":[{"name":"Ginekolo\u0161ko-aku\u0161erska klinika, Klini\u010dki centar, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6731-8596","authenticated-orcid":false,"given":"Djuro","family":"Macut","sequence":"additional","affiliation":[{"name":"Klinika za endokrinologiju, dijabetes i bolesti metabolizma, Klini\u010dki centar Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:32:36Z","timestamp":1685356356000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791210583M"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":0,"journal-issue":{"issue":"9-10","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1210583m","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"type":"print","value":"0370-8179"},{"type":"electronic","value":"2406-0895"}],"subject":[],"published":{"date-parts":[[2012]]}}}