{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:56:19Z","timestamp":1747209379976,"version":"3.40.5"},"reference-count":0,"publisher":"National Library of Serbia","issue":"1-2","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Introduction. Sarcoidosis is an antigen-mediated disease of unknown cause\n   defined by granulomatous inflammation of different organs. Objective. The aim\n   of this study was to analyze the clinical picture in 26 patients with a\n   definitive and presumed ocular sarcoidosis. Methods. The following tests were\n   conducted: angiotensin-converting enzyme, tuberculin skin test, liver enzymes\n   and calcium in urine and serum. Enlarged hilar lymph glands were diagnosed\n   using X-ray tomography or computed tomography of the mediastinum. A biopsy of\n   lymph glands was performed either transbronchially or transmediastinally.\n   Ophthalmic examination included biomicroscopic examination, intraocular\n   pressure measurement, photofundus, fluorescein angiography, optical coherence\n   tomography and computerized perimetry. Results. The average follow-up period\n   of the disease was 6.1 years. The average age was 52.0 years. There were\n   62.5% female patients, with bilateral incidence of 69.2%. The clinical\n   picture included: panuveitis (in 30.8% of patients), anterior uveitis\n   (26.9%), posterior uveitis (26.9%), intermediate uveitis (7.7%) and vitritis\n   in (7.7%). The following complications were observed: cataract (in 34.6% of\n   patients), cystoid macular edema (23.1%), glaucoma (15.4%), macroaneurysms\n   (15.4%), neovascularization (7.7%) and band keratopathy (3.8%). There was a\n   statistically significant difference in the visual acuity (p=0.033) and\n   severity of clinical symptoms (p=0.02) between the groups of patients with\n   retinal vasculitis associated with ?candle-wax? phenomenon and the group of\n   patients with multiple chorioretinal lesions - ?white dot? syndrome.\n   Conclusion. To our consideration, the differences observed between the two\n   groups are the result of retinal vasculitis and subsequent macular edema,\n   which is significantly more frequent in the group with ?candle-wax?\n   phenomenon.<\/jats:p>","DOI":"10.2298\/sarh1302013j","type":"journal-article","created":{"date-parts":[[2013,4,24]],"date-time":"2013-04-24T10:28:16Z","timestamp":1366799296000},"page":"13-16","source":"Crossref","is-referenced-by-count":0,"title":["Clinical profile of presumed and definitive ocular sarcoidosis"],"prefix":"10.2298","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9003-4404","authenticated-orcid":false,"given":"Svetlana","family":"Jovanovic","sequence":"first","affiliation":[{"name":"Klini\u010dki centar Kragujevac, Klinika za o\u010dne bolesti, Kragujevac + Medicinski fakultet, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6997-7715","authenticated-orcid":false,"given":"Gordana","family":"Zlatanovic","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar, Klinika za o\u010dne bolesti, Ni\u0161 + Medicinski fakultet, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9040-9031","authenticated-orcid":false,"given":"Zorica","family":"Jovanovic","sequence":"additional","affiliation":[{"name":"Medicinski fakultet, Odeljenje za patofiziologiju, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filip","family":"Radotic","sequence":"additional","affiliation":[{"name":"Medicinski fakultet, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:32:59Z","timestamp":1685356379000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791302013J"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":0,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1302013j","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"type":"print","value":"0370-8179"},{"type":"electronic","value":"2406-0895"}],"subject":[],"published":{"date-parts":[[2013]]}}}