{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T03:21:29Z","timestamp":1792984889051,"version":"4.5.0"},"reference-count":0,"publisher":"National Library of Serbia","issue":"3-4","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004564","name":"Ministry of Education, Science and Technological Development of the Republic of Serbia","doi-asserted-by":"publisher","award":["41008"],"award-info":[{"award-number":["41008"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Introduction. Oxidative stress and antioxidants play an important role in the\n   pathogenesis of inflammatory disease, including chronic periodontitis (CP).\n   Saliva contains enzymatic (glutathione peroxidase - GPx, superoxide dismutase\n   - SOD, etc.) and non-enzymatic (albumin - ALB, uric acid - UA, glutathione,\n   etc.) antioxidants. Objective. The aims of this study were to investigate: a)\n   level of SOD, GPx, UA, ALB and total antioxidative status (TAS) of saliva in\n   CP patients before and after non-surgical treatment, and b) correlations\n   between clinical periodontal parameters and levels of salivary antioxidants.\n   Methods. Saliva was collected from 21 CP patients before and after\n   non-surgical treatment. The condition of periodontium was assessed by plaque\n   index, gingival index, bleeding on probing, probing depth and clinical\n   attachment loss. Level of investigated antioxidants (except GPx) and TAS was\n   determined using colorimetric method and commercial kits. GPx activity was\n   determined using UV method and commercial kits. Results. After the treatment\n   significant increase of UA, ALB, Gpx, TAS was detected (p&lt;0.01) and decrease\n   of SOD activity (p&gt;0.05). A significant correlation was observed between GPx\n   and PI (r=0.575, p=0.008), SOD and GI (r=0.525, p=0.017) before therapy, and\n   SOD and bleeding on probing (BP) (r=0.59, p=0.006), TAS and BP (r=0.453,\n   p=0.045) after therapy. Conclusion. These data suggest that levels of\n   salivary antioxidants generally increase after non-surgical periodontal\n   treatment. Correlation between some clinical periodontal parameters and level\n   of salivary antioxidants was found.<\/jats:p>","DOI":"10.2298\/sarh1304163n","type":"journal-article","created":{"date-parts":[[2013,5,22]],"date-time":"2013-05-22T13:02:31Z","timestamp":1369227751000},"page":"163-168","source":"Crossref","is-referenced-by-count":38,"title":["Antioxidative status of saliva before and after non-surgical periodontal treatment"],"prefix":"10.2298","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7086-298X","authenticated-orcid":false,"given":"Nada","family":"Novakovic","sequence":"first","affiliation":[{"name":"ZU stomatolo\u0161ka ordinacija \u201eVera\u201c, Zvornik, Republika Srpska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasa","family":"Cakic","sequence":"additional","affiliation":[{"name":"Stomatolo\u0161ki fakultet, Klinika za parodontologiju i oralnu medicinu, Beograd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatjana","family":"Todorovic","sequence":"additional","affiliation":[{"name":"Stomatolo\u0161ki fakultet, OJ institutski predmeti Biohemija, Beograd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biljana","family":"Andjelski-Raicevic","sequence":"additional","affiliation":[{"name":"Stomatolo\u0161ki fakultet, OJ institutski predmeti Biohemija, Beograd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Dozic","sequence":"additional","affiliation":[{"name":"Stomatolo\u0161ki fakultet, OJ institutski predmeti Biohemija, Beograd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanja","family":"Petrovic","sequence":"additional","affiliation":[{"name":"Stomatolo\u0161ki fakultet, Klinika za de\u010dju i preventivnu stomatologiju, Beograd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neda","family":"Perunovic","sequence":"additional","affiliation":[{"name":"Stomatolo\u0161ki fakultet, Klinika za parodontologiju i oralnu medicinu, Beograd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanja","family":"Spadijer-Gostovic","sequence":"additional","affiliation":[{"name":"Stomatolo\u0161ki fakultet, Klinika za stomatolo\u0161ku protetiku, Beograd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Kadovic-Sretenovic","sequence":"additional","affiliation":[{"name":"Dom zdravlja, Stomatolo\u0161ka slu\u017eba, Bogati\u0107"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emina","family":"Colak","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Srbije, Institut za medicinsku biohemiju, Beograd"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:33:09Z","timestamp":1685356389000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791304163N"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":0,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1304163n","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"value":"0370-8179","type":"print"},{"value":"2406-0895","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}