{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T04:10:10Z","timestamp":1685419810060},"reference-count":0,"publisher":"National Library of Serbia","issue":"7-8","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Introduction. Recurrent depression is a psychiatric disorder of which\n   etiology and pathogenesis might be related to immune response. Metabolic\n   Syndrome (MetS) and its components are also strongly associated with elevated\n   inflammatory indicators, as so as the body mass index (BMI) and total\n   cholesterol levels. Objective. Objective of this study was to investigate if\n   there was any difference in C-reactive protein (CRP) levels in patients with\n   recurrent depressive disorder, treated with antidepressants, compared to a\n   healthy control group of subjects and if there was an association between\n   increased CRP levels and the presence of MetS in these two groups. Methods.\n   Sixty subjects entered the study; of these 35 patients with the diagnosis of\n   recurrent depressive disorder, while the healthy control group included 25\n   subjects. MetS was defined according to the NCEP ATP III criteria. The\n   cut-off point for CRP was set at &gt;5 mg \/L. Results. There was no\n   statistically significant difference in the prevalence of MetS and CRP values\n   between the studied groups. Waist circumference and total cholesterol levels\n   were significantly higher in the experimental group. Patients that fulfilled\n   the criteria for MetS showed significantly higher values of central obesity\n   and arterial hypertension in the experimental group as well. The elevated CRP\n   levels were associated with increased frequency of MetS in depressed\n   patients. Conclusion. Both CRP levels and metabolic risk profile screening,\n   according to the international criteria, may be beneficial in order to obtain\n   better assessment for depressive long term medicated patients.<\/jats:p>","DOI":"10.2298\/sarh1308511s","type":"journal-article","created":{"date-parts":[[2013,11,6]],"date-time":"2013-11-06T09:34:07Z","timestamp":1383730447000},"page":"511-515","source":"Crossref","is-referenced-by-count":3,"title":["Metabolic syndrome and C-reactive protein in patients with depressive disorder on antidepressive medication"],"prefix":"10.2298","volume":"141","author":[{"given":"Albina","family":"Stanojevic","sequence":"first","affiliation":[{"name":"Specijalna bolnica za psihijatrijske bolesti \u201eGornja Toponica\u201c, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irena","family":"Popovic","sequence":"additional","affiliation":[{"name":"Specijalna bolnica za psihijatrijske bolesti \u201eGornja Toponica\u201c, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milutin","family":"Nenadovic","sequence":"additional","affiliation":[{"name":"Specijalna bolnica za psihijatrijske bolesti \u201eLaza Lazarevi\u0107\u201c, Beograd + Medicinski fakultet, Kosovska Mitrovica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragan","family":"Ravanic","sequence":"additional","affiliation":[{"name":"Medicinski fakultet, Katedra za psihijatriju, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordana","family":"Paunovic-Milosavljevic","sequence":"additional","affiliation":[{"name":"Narodna skup\u0161tina Republike Srbije, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:33:34Z","timestamp":1685356414000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791308511S"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":0,"journal-issue":{"issue":"7-8","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1308511s","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"value":"0370-8179","type":"print"},{"value":"2406-0895","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}