{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:48:19Z","timestamp":1760888899556,"version":"3.37.3"},"reference-count":0,"publisher":"National Library of Serbia","issue":"1-2","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004564","name":"Ministry of Education, Science and Technological Development of the Republic of Serbia","doi-asserted-by":"publisher","award":["175075"],"award-info":[{"award-number":["175075"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Introduction. Periodontitis is a destructive inflammatory disease of the\n   tooth-supporting tissues, primarily caused by Gram-negative microorganisms.\n   Thus, the primary objective of cause-related initial periodontal therapy is\n   disruption and removal of the subgingival biofilm. Objective. The aim of this\n   study was to evaluate the clinical and microbiological effects of the initial\n   therapy in patients diagnosed with chronic periodontitis. Methods. Forty\n   patients with chronic periodontitis were included in the study. As a part of\n   the clinical assessment undertaken prior to the initial therapy, as well as\n   one month and three months post-therapy, plaque index, gingival index,\n   papilla bleeding index, probing pocket depth and clinical attachment level\n   were recorded. Microbiological testing was performed prior to the initial\n   therapy and three months after therapy. Polymerase chain reaction assays were\n   used to determine the presence of Porphyromonas gingivalis, Tannerella\n   forsythensis, Prevotella intermedia and Aggregatibacter\n   actinomycetemcomitans. Results. All clinical parameters were significantly\n   reduced after therapy. The prevalence of Aggregatibacter\n   actinomycetemcomitans was reduced by 22.5%, which was a statistically\n   significant decrease compared to the baseline. The prevalence of\n   Porphyromonas gingivalis, Tannerella forsythensis and Prevotella intermedia\n   tended to decrease after therapy; however, the difference did not reach\n   statistical significance. Conclusion. The results of the present study\n   demonstrated the beneficial effects of the initial periodontal therapy on\n   both the clinical and microbiological parameters.<\/jats:p>","DOI":"10.2298\/sarh1402010p","type":"journal-article","created":{"date-parts":[[2014,4,14]],"date-time":"2014-04-14T11:10:21Z","timestamp":1397473821000},"page":"10-16","source":"Crossref","is-referenced-by-count":3,"title":["Clinical and microbiological effects of the initial periodontal therapy"],"prefix":"10.2298","volume":"142","author":[{"given":"Tanja","family":"Predin","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milanko","family":"Djuric","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Novi Sad + Dental Clinic of Vojvodina, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jelena","family":"Mirnic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3638-9690","authenticated-orcid":false,"given":"Ivana","family":"Gusic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Novi Sad + Dental Clinic of Vojvodina, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadja","family":"Nikolic","sequence":"additional","affiliation":[{"name":"School of Dentistry, Department of Human Genetics, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dubravka","family":"Markovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Novi Sad + Dental Clinic of Vojvodina, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Andjelkovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Novi Sad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6225-7210","authenticated-orcid":false,"given":"Jelena","family":"Milasin","sequence":"additional","affiliation":[{"name":"School of Dentistry, Department of Human Genetics, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T10:34:13Z","timestamp":1685356453000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791402010P"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":0,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1402010p","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"type":"print","value":"0370-8179"},{"type":"electronic","value":"2406-0895"}],"subject":[],"published":{"date-parts":[[2014]]}}}