{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:24:04Z","timestamp":1762017844277},"reference-count":0,"publisher":"National Library of Serbia","issue":"3-4","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Introduction. Brain metastases from epithelial ovarian cancer (EOC) are rare\n   events. We present a rare case of single ovarian cancer metastasis to the\n   brain treated with gamma-knife radiosurgery (GKRS). Case Outline. A\n   65-year-old woman with advanced EOC presented with severe neurologic\n   symptoms. A single brain metastasis of 3.2 cm with surrounding edema in the\n   left parietal lobe was detected by brain magnetic resonance imaging (MRI)\n   scan during the work-up. The decision to perform GKRS was due to a surgical\n   inaccessibility of intracranial lesion. Twelve weeks after the procedure, the\n   MRI scan showed reduction in the diameter of brain metastasis and surrounding\n   edema and the patient returned to good mental and motor performance. The\n   patient survived for 22 months following treatment and died from a\n   progressive intra-abdominal disease. Prognosis of ovarian cancer patients\n   with brain metastases is generally poor regardless of treatment. Conclusion.\n   Our case shows that GKRS as primary treatment modality for the control of\n   ovarian cancer metastases to the brain was effective and can be considered as\n   a treatment of choice if international selection criteria are followed.<\/jats:p>","DOI":"10.2298\/sarh1504205n","type":"journal-article","created":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T14:13:38Z","timestamp":1428329618000},"page":"205-209","source":"Crossref","is-referenced-by-count":5,"title":["Management of brain metastasis in a patient with advanced epithelial ovarian carcinoma by gamma-knife radiosurgery"],"prefix":"10.2298","volume":"143","author":[{"given":"Marinos","family":"Nikolaou","sequence":"first","affiliation":[{"name":"General Hospital of Agios Nikolaos, Department of Obstetrics and Gynecology, Lasithi, Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srdjan","family":"Stamenkovic","sequence":"additional","affiliation":[{"name":"University Women\u2019s Hospital in Neuenheimer Feld, Department of Obstetrics and Gynecology, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christos","family":"Stergiou","sequence":"additional","affiliation":[{"name":"Hygeia Hospital, Marousi, Ganmma Knife Department, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christos","family":"Skarleas","sequence":"additional","affiliation":[{"name":"Hygeia Hospital, Marousi, Ganmma Knife Department, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Torrens","sequence":"additional","affiliation":[{"name":"Hygeia Hospital, Marousi, Ganmma Knife Department, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T09:56:46Z","timestamp":1685354206000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791504205N"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":0,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1504205n","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"value":"0370-8179","type":"print"},{"value":"2406-0895","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}