{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:11:21Z","timestamp":1762866681678},"reference-count":0,"publisher":"National Library of Serbia","issue":"7-8","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Srp Arh Celok Lek","SRP ARH CELOK LEK","SRP ARK CELOK LEK","SRPSKI ARHIV CELOKUP"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Introduction. Streptococcal necrotizing fasciitis (NF) is a serious soft\n   tissue infection with rapid progression of inflammatory process among\n   superficial or deep fascia, systemic host response to infection leading to\n   toxic shock syndrome (TSS), and multiple organ failure. Lethality is high.\n   Case Outline. A 46-year-old male without co-morbidities was admitted to the\n   Emergency Department with redness, swelling and pain on his right lower leg.\n   He became sick two day s ea rlier with m alaise, chills and shivering. On\n   admission he was hypotensive, anuric, with erythematous rash on his face,\n   neck and chest, with acute ren al failure and elevated creatine phosphokinase\n   level. During the next several hours, the changes on his right lower leg\n   rapidly spread to the whole leg, followed by skin destruction and subcutaneo\n   us bleeding, indicating NF. Aggressive antimicrobial, supportive and symptom\n   atic therapy was initiated immediately and on the same evening surgical\n   intervention was performed. Despite these measures, a rapid development of\n   severe TSS, with lethal outcome, occurred in less than 40 hours after the\n   admission. Stre ptococcus pyogenes (group A ?-hemolytic Streptococcus) was\n   isolated from the throat, skin and tissue obtained duri ng the surgery.\n   Conclusion. Necrotizing fasciitis is a very serious disease with unpre\n   dictable course. For that reason doctors must devote a great deal of a\n   ttention to early, i.e. timely diagnosis of this disease, whose treatment\n   with a multid isciplinary approach is very important.<\/jats:p>","DOI":"10.2298\/sarh1508476k","type":"journal-article","created":{"date-parts":[[2015,9,9]],"date-time":"2015-09-09T13:15:16Z","timestamp":1441804516000},"page":"476-479","source":"Crossref","is-referenced-by-count":7,"title":["Streptococcal necrotizing fasciitis with toxic shock syndrome and rapid fatal outcome"],"prefix":"10.2298","volume":"143","author":[{"given":"Miroslav","family":"Kojic","sequence":"first","affiliation":[{"name":"Military Medical Academy, Clinic for Infectious and Tropical Diseases, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragan","family":"Mikic","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Clinic for Infectious and Tropical Diseases, Belgrade + University of Defense, Faculty of Medicine, Military Medical Academy, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darko","family":"Nozic","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Clinic for Infectious and Tropical Diseases, Belgrade + University of Defense, Faculty of Medicine, Military Medical Academy, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bojan","family":"Rakonjac","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Institute for Microbiology, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Srpski arhiv za celokupno lekarstvo"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T09:57:10Z","timestamp":1685354230000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0370-81791508476K"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":0,"journal-issue":{"issue":"7-8","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.2298\/sarh1508476k","relation":{},"ISSN":["0370-8179","2406-0895"],"issn-type":[{"value":"0370-8179","type":"print"},{"value":"2406-0895","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}