{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:22:33Z","timestamp":1762503753848},"reference-count":17,"publisher":"National Library of Serbia","issue":"8","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2006]]},"abstract":"<jats:p>Background. Parathyroid carcinoma is the least frequent malignancy among endocrine tumors. In the most reported series of patients with primary hyperparathyroidism the incidence of carcinoma is less than 1%. Recognition by a surgeon that the parathyroid tumor is malignant, and the performance of an adequate en bloc removal of primary lesion, with histologic diagnosis offer the best treatment of a patient with this unusual malignancy. Case report. We reported a 30-year-old patient with parathyroid carcinoma, primary hyperparathyroidism, and recurrent nephrocalcinosis. Marked hypercalcemia, low serum phosphorus, and substantial elevation of serum parathyroid hormone indicated a diagnosis of primary hiperparathyroidism. General symptoms were anorexia, muscle weakness, back pain and depression. Ultrasonography done before the surgery revealed a 2 cm upper left parathyroid gland with solid and cystic areas. The neck exploration was done with en block resection of the tumor. A histopathological evaluation confirmed the diagnosis of parathyroid carcinoma. Over more than a three-year-follow-up, the patient had no evidence of the disease recurrence and his serum PTH and calcium levels remained within the normal. Conclusion. Parathyroid carcinoma is a rare cause of primary hyperparathyroidism. Preoperative diagnosis remains a challenge. Radical en bloc resection of the tumor is the treatment of choice for this malignancy.<\/jats:p>","DOI":"10.2298\/vsp0608765f","type":"journal-article","created":{"date-parts":[[2010,12,10]],"date-time":"2010-12-10T11:31:44Z","timestamp":1291980704000},"page":"765-769","source":"Crossref","is-referenced-by-count":1,"title":["Parathyroid carcinoma"],"prefix":"10.2298","volume":"63","author":[{"given":"Aleksandar","family":"Filipovic","sequence":"first","affiliation":[{"name":"Klini\u010dki centar Crne Gore, Hirur\u0161ka klinika, Podgorica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Paunovic","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Srbije, Centar za endokrinu hirurgiju, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragutin","family":"Savjak","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Crne Gore, Institut za patologiju, Podgorica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Zivkovic","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Crne Gore, Hirur\u0161ka klinika, Podgorica"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-7404(99)00037-7"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(85)80050-7"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199101000-00010"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930301)71:5<1923::AID-CNCR2820"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S0147-0272(85)80035-0"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/BF01665308"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-4-10"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199204000-00002"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/BF02067369"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.136.8.878"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199308000-00007"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199207000-00002"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/BF01655520"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930520105"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/BF01670531"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1053\/hupa.2003.55"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200404000-00007"}],"container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:04:57Z","timestamp":1685358297000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84500608765F"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2006]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp0608765f","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"value":"0042-8450","type":"print"},{"value":"2406-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}