{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T04:05:52Z","timestamp":1685419552818},"reference-count":27,"publisher":"National Library of Serbia","issue":"11","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;zakljucak&gt; Hepatorenalni sindrom je funkcionalna insuficijencija bubrega u sklopu terminalne insuficijencije jetre. U patogenezi ovog sindroma ucestvuju hemodinamske promene (snizeni srednji arterijski pritisak i perfuzioni pritisak bubrega) i povecano stvaranje sistemskih i bubreznih vazoaktivnih medijatora sa stimulacijom bubreznog simpatickog sistema. Standardna medicinska farmakoloska terapija usmerena je na prethodno navedene patofizioloske poremecaje. U poslednje vreme postupci detoksikacije, npr. jedan od vidova albuminske dijalize, pojavljuju se sve vise u lecenju bolesnika sa HRS, ali se jos ne preporucuju kao standardna procedura. Oba vida lecenja preduzimaju se samo kao premoscenje perioda do transplantacije jetre ili u slucajevima kada se ocekuje oporavak funkcije jetre, jer bubrezna funkcija direktno zavisi od funkcije jetre. Standardna hemodijaliza ne pomaze u poboljsanju funkcije bubrega. Jedino kauzalno resenje ovog problema donosi transplantacija jetre.<\/jats:p>","DOI":"10.2298\/vsp0711773k","type":"journal-article","created":{"date-parts":[[2010,12,10]],"date-time":"2010-12-10T11:34:32Z","timestamp":1291980872000},"page":"773-777","source":"Crossref","is-referenced-by-count":0,"title":["Treatment of hepatorenal syndrome"],"prefix":"10.2298","volume":"64","author":[{"given":"Aleksandra","family":"Kezic","sequence":"first","affiliation":[{"name":"Klini\u010dki centar Srbije, Nefrolo\u0161ka klinika, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragana","family":"Mijac","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Srbije, Institut za bolesti digestivnog sistema, Klinika za gastroenterologiju i hepatologiju, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biljana","family":"Stojimirovic","sequence":"additional","affiliation":[{"name":"Klini\u010dki centar Srbije, Nefrolo\u0161ka klinika, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.49.5.729"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.33575"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2003.10.007"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14903-3"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21094"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.2174\/138161206779010413"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510270107"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(96)80297-2"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s11938-005-0030-z"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2006.03086.x"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2002.02816.x"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1080\/00365520500527441"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510280407"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-006-9312-0"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1594.2002.06822.x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(02)00334-3"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(03)00468-9"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.17.s3.14.x"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1053\/lv.2000.6355"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1023\/B:MEBR.0000043972.50878.f0"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-9987.2006.00354.x"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2006.00215.x"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1186\/cc4985"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1594.2002.06931_1.x"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/13.1.20"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfi212"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20445"}],"container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:05:53Z","timestamp":1685358353000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84500711773K"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":27,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp0711773k","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"value":"0042-8450","type":"print"},{"value":"2406-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}