{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T12:27:44Z","timestamp":1754483264633},"reference-count":0,"publisher":"National Library of Serbia","issue":"9","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Background\/Aim. Bleeding from peptic ulcers can be effectively and safely\n   treated with endoscopic hemoclips therapy. However, due to certain limiting\n   factors of hemoclips, application of combination with another endoscopic\n   method may give better results. The aim of this study was to examine the\n   efficacy and safety of endoscopic hemoclips therapy and to evaluate potential\n   benefits of this therapy combined with epinephrine in the treatment of\n   bleeding peptic ulcers. Methods. This prospective randomized study included\n   70 patients with bleeding gastric or duodenal ulcer. In 34 of the patients\n   endoscopic hemoclips therapy was applied (group I), and in 36 of them a\n   combined therapy of hemoclips and epinephrine (group II). Results. Initial\n   hemostasis was achieved in most patients treated with endoscopic hemoclips\n   therapy (94.1%) as well as in the patients treated with combination therapy\n   (97.2%). After initial hemostasis achieved rebleeding occurred in 3 (9.3%)\n   patients treated with hemoclips and in 2 (5.7%) patients treated with\n   combination therapy, but this difference was not statistically significant (p\n   &gt; 0.05). The difference in the achieved final hemostasis between the group I\n   (91.1%) and the group II (94.4%) was not statistically significant. Also, the\n   differences between the two groups of patients in the need for blood\n   transfusions, length of hospital stay, need for surgery and mortality were\n   not statistically significant (p &gt; 0.05). Conclusion. Endoscopic hemoclips\n   therapy is effective and safe in treatment of bleeding peptic ulcers.\n   Combination therapy of hemoclips and epinephrine has no advantage over\n   hemoclips monotherapy.<\/jats:p>","DOI":"10.2298\/vsp110411009g","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T12:06:38Z","timestamp":1361966798000},"page":"824-829","source":"Crossref","is-referenced-by-count":6,"title":["Could application of epinephrine improve hemostatic efficacy of hemoclips for bleeding peptic ulcers? A prospective randomized study"],"prefix":"10.2298","volume":"70","author":[{"given":"Sasa","family":"Grgov","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, General Hospital Leskovac, Leskovac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biljana","family":"Radovanovic-Dinic","sequence":"additional","affiliation":[{"name":"Clinic for Gastroenterology and Hepatology, Clinical Center Ni\u0161, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomislav","family":"Tasic","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, General Hospital Leskovac, Leskovac"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:11:47Z","timestamp":1685358707000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84501300009G"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp110411009g","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"value":"0042-8450","type":"print"},{"value":"2406-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}