{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:41:29Z","timestamp":1777909289512,"version":"3.51.4"},"reference-count":6,"publisher":"National Library of Serbia","issue":"8","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Background\/Aim. Drug abuse remains a significant social problem in many\n   countries. The aim of the study was to estimate association between pulmonary\n   histopathological changes and results of toxicological analyses in forensic\n   autopsies of illicit drug users. Methods. This investigation was performed in\n   the Institute of Forensic Medicine, Belgrade, and in the Clinical Center,\n   Department of Forensic Medicine, Kragujevac, from 2000 to 2004, and included\n   63 medicolegal autopsies of heroin or other drug consumers who suddenly died.\n   Autopsies, postmortem toxicological examination of drugs and serological\n   analyses of anti- HIV\/HBV\/HCV antibodies were performed. Results. The\n   deceased persons were mostly male, 46\/63 (73.01%), ranged in age from 19 to\n   49 years (mean 31 years) and all were whites. Postmortem toxicological\n   examination was performed on all of the deceased persons and drugs in the\n   fatal range were identified in only eight of them (12.7%), in the toxic range\n   in ten (15.87%), and in minimal concentrations in 35 (55.56%) of the deceased\n   persons. Drugs identified in the fatal, toxic or minimal range included\n   heroin-morphine (38\/53), cocaine (4\/53), tramadol (3\/53), and lorazepam\n   (1\/53). In the 7 remaining subjects, ethanol in combination with heroin was\n   found in 4 cases, and diazepam in combination with heroin in 3 cases.\n   Dominant pathomorphological changes were findings in the lung tissue. Most\n   common histological changes observed in drug users were pulmonary edema -\n   55\/63 (87.3%), acute alveolar hemorrhages - 49\/63 (77.78%), hemosiderin-laden\n   macrophages (siderophages) - 52\/63 (82,54%), and emphysematous changes -\n   51\/63 (80,95%). Conclusion. Pulmonary edema is the frequent non-specific\n   autopsy finding which is associated with virtually all routes of drug\n   administration. The histopatological study is necessary to determinate a\n   cause of death when a deceased person has the history of dependence or abouse\n   of psychoactive drugs with negative toxicological results.<\/jats:p>","DOI":"10.2298\/vsp1108639t","type":"journal-article","created":{"date-parts":[[2011,8,23]],"date-time":"2011-08-23T12:17:58Z","timestamp":1314101878000},"page":"639-642","source":"Crossref","is-referenced-by-count":8,"title":["Association of pulmonary histopathological findings with toxicological findings in forensic autopsies of illicit drug users"],"prefix":"10.2298","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6166-7103","authenticated-orcid":false,"suffix":"S.","given":"Milos","family":"Todorovic","sequence":"first","affiliation":[{"name":"School of Medicine, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slobodanka","family":"Mitrovic","sequence":"additional","affiliation":[{"name":"School of Medicine, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Branimir","family":"Aleksandric","sequence":"additional","affiliation":[{"name":"School of Medicine, Institute of Forensic Medicine, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nenad","family":"Mladjenovic","sequence":"additional","affiliation":[{"name":"Clinical Center Kragujevac, Department of Forensic Medicine, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6422-5354","authenticated-orcid":false,"given":"Suzana","family":"Matejic","sequence":"additional","affiliation":[{"name":"School of Medicine, Kragujevac"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.91.4.596"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1136\/ewjm.172.1.11"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0376-8716(03)00191-1"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(72)80053-4"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(71)90298-1"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.93.2.427"}],"container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:10:03Z","timestamp":1685358603000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84501108639T"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":6,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp1108639t","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"value":"0042-8450","type":"print"},{"value":"2406-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}