{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T04:07:53Z","timestamp":1685419673345},"reference-count":0,"publisher":"National Library of Serbia","issue":"4","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Introduction. Acroangiodermatitis is a rare skin disease characterized by\n   hyperplasia of pre-existing vasculature due to venous hypertension from\n   severe chronic venous stasis. Clinical appearance of this condition is often\n   similar to Kaposi sarcoma and is creating serious differential diagnostic\n   difficulties. Case report. A patient with acroangiodermatitis was presented\n   and the differential diagnosis discussed. Examination of the patella of the\n   affected area showed grayish-blue to brown infiltrates and reduced\n   elasticity, located in the supra- and infrapatellar regions. Clinically,\n   Kaposi?s sarcoma was suspected. Histopathologically there were acanthosis and\n   compact hyperkeratosis. The underlying papillary dermis showed fibrosis and\n   edema. A subepidermal lobular vascular proliferation with hemosiderin\n   deposition was also noted. This consisted of multiple newly formed\n   capillaries, featuring small blood vessels with dilated, rounded lumina.\n   Serologies for HIV and Borrelia burgdorferi were negative, as was a HHV-8 PCR\n   in lesional tissue. Doppler analysis of the vessels of the extremities showed\n   chronic venous insufficiency, insufficiency of v. perforantes, insufficiency\n   of the Cockett II-III. No deep thromboses in the area of the shank and thigh\n   were found. Initially, treatment consisted of clindamycin 600 mg 3 times per\n   day, intravenously, during a 2-week period. After that the treatment was\n   continued with prednisolone, 30 mg daily in combination with furosemide 40\n   mg\/day, as well as lymph drainage and adequate compression therapy. The\n   consequent clinical improvement allowed the patient to be discharged from the\n   clinic. Conclusion. The most important differential diagnostic marker in\n   distinguishing between acroangiodermatitis and Kaposi sarcoma seems to be the\n   confirmation of the presence of genetic material of HHV-8 in the affected\n   skin areas in patients with Kaposi sarcoma.<\/jats:p>","DOI":"10.2298\/vsp1204370t","type":"journal-article","created":{"date-parts":[[2012,4,9]],"date-time":"2012-04-09T07:29:45Z","timestamp":1333956585000},"page":"370-373","source":"Crossref","is-referenced-by-count":0,"title":["Unilateral presentation of pseudo-Kaposi\u2019s acroangiodermatitis: A diagnostic and therapeutic challenge"],"prefix":"10.2298","volume":"69","author":[{"given":"Georgi","family":"Tchernev","sequence":"first","affiliation":[{"name":"Polyclinic of Dermatology and Venerology, University Hospital Lozenetz, Medical Faculty, Saint Kliment Ohridski University, Sofia, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"W.","given":"James","family":"Patterson","sequence":"additional","affiliation":[{"name":"Division of Surgical Pathology and Cytopathology, University of Virginia Hospital, Charlottesville, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Ananiev","sequence":"additional","affiliation":[{"name":"Department of General and Clinical Pathology, Medical Faculty, Trakian University, Stara Zagora, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Tronnier","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Klinikum Hildesheim GmbH, Hildesheim, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:11:05Z","timestamp":1685358665000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84501204370T"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp1204370t","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"value":"0042-8450","type":"print"},{"value":"2406-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}