{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:20:28Z","timestamp":1777483228272,"version":"3.51.4"},"reference-count":0,"publisher":"National Library of Serbia","issue":"5","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Introduction. Disulfiram is used in the treatment of chronic alcoholism,\n   because of the unpleasant symptoms produced after ethanol intake. Although it\n   is well tolerated in most patients, one in 15,000 patients will develop\n   peripheral neuropathy every year, which is frequently misdiagnosed as\n   alcoholic neuropathy. Case report. We report clinical, laboratory,\n   electrophysiological and histopathological features in a 19-year-old patient\n   who developed an acute distal sensorymotor neuropathy during the treatment of\n   alcoholism. At the end of 4-month treatment with disulfiram 250 mg\/day, the\n   patient complained of weakness in distal segments of the lower limbs\n   associated with burning dysesthesias, numbness and pain in the soles of the\n   feet and the legs below the knees; reduction in foot strength, the absence of\n   ankle jerk tendon reflexes, and tactile stocking pin-pick and vibratory\n   sensory impairment in the lower limbs below the knee. Recovery was successful\n   after treatment cessation. Conclusion. The significance of toxic neuropathy\n   is shown by the fact that the recognition of clinical picture, identifying\n   etiological factors and its elimination may prevent the evolution of\n   polyneuropathy. This allows for more effective treatment of these\n   neuropathies as apposite to idiopathic ones which can be treated only\n   symptomatically. Our case report indicates the possibilities during a period\n   with no serious damage to the axons manifested.<\/jats:p>","DOI":"10.2298\/vsp1205453v","type":"journal-article","created":{"date-parts":[[2012,5,15]],"date-time":"2012-05-15T07:26:58Z","timestamp":1337066818000},"page":"453-475","source":"Crossref","is-referenced-by-count":2,"title":["Disulfiram-induced polyneurophaty"],"prefix":"10.2298","volume":"69","author":[{"given":"Slavica","family":"Vujisic","sequence":"first","affiliation":[{"name":"Neurolo\u0161ka klinika, Klini\u010dki centar Crne Gore, Podgorica, Crna Gora"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ljiljana","family":"Radulovic","sequence":"additional","affiliation":[{"name":"Neurolo\u0161ka klinika, Klini\u010dki centar Crne Gore, Podgorica, Crna Gora"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sladjana","family":"Knezevic-Apostolski","sequence":"additional","affiliation":[{"name":"Neurolo\u0161ka klinika, Vojnomedicinska akademija, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stevan","family":"Petkovic","sequence":"additional","affiliation":[{"name":"Privatni dom zdravlja \u201eDr Risti\u0107\u201c, Novi Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filip","family":"Vukmirovic","sequence":"additional","affiliation":[{"name":"Centar za patologiju i sudsku medicinu, Klini\u010dki centar Crne Gore, Podgorica, Crna Gora"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slobodan","family":"Apostolski","sequence":"additional","affiliation":[{"name":"Specijalisti\u010dka ordinacija za neurologiju \u201eApostolski\u201c, Beograd"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:11:11Z","timestamp":1685358671000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84501205453V"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp1205453v","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"value":"0042-8450","type":"print"},{"value":"2406-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}