{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T18:10:08Z","timestamp":1740161408931,"version":"3.37.3"},"reference-count":0,"publisher":"National Library of Serbia","issue":"12","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004564","name":"Ministry of Education, Science and Technological Development of the Republic of Serbia","doi-asserted-by":"publisher","award":["175092"],"award-info":[{"award-number":["175092"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Introduction. Primary acinic cell carcinoma (ACC) is an uncommon malignant\n   neoplasm of the salivary gland (SG), which usually presents as slow growing\n   tumor. Case report. We reported a 69-year-old woman with tumor in the right\n   parotid gland with a 5-year progress. Biopsy sections revealed a hybrid form\n   of ACC with a low- and high-grade component and prominent lymphoid tissue in\n   tumor stroma. Immunohistochemistry was performed to define the molecular\n   profile of this unusual ACC, with special interest for stromal influence on\n   to the proliferative activity of ACC with dedifferentiation. We detected that\n   the level and the type of stromal lymphoid reaction (particularly CD8+\/CD4+\n   ratio) had a significant influence on to Ki-67 index in the high-grade\n   component of ACC, as well as the involvement of the CXCR4 signaling axis in\n   the stromal reaction influence. Conclusion. We suggest that tumor stroma may\n   be a source of potential new tumor biomarkers which can determine the\n   aggressivity of this tumor.<\/jats:p>","DOI":"10.2298\/vsp1312155j","type":"journal-article","created":{"date-parts":[[2013,12,9]],"date-time":"2013-12-09T10:26:45Z","timestamp":1386584805000},"page":"1155-1158","source":"Crossref","is-referenced-by-count":0,"title":["Stromal reaction and prognosis in acinic cell carcinoma of the salivary gland"],"prefix":"10.2298","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1957-734X","authenticated-orcid":false,"given":"Ljubinka","family":"Jankovic-Velickovic","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Institute of Pathology, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irena","family":"Dimov","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Immunology, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragan","family":"Petrovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Clinic of Stomatology, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slavica","family":"Stojnev","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Institute of Pathology, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Dacic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Clinic of Stomatology, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Velickovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Clinic of Stomatology, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladisav","family":"Stefanovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Institute of Nephrology, Ni\u0161"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:13:13Z","timestamp":1685358793000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84501312155J"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp1312155j","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"type":"print","value":"0042-8450"},{"type":"electronic","value":"2406-0720"}],"subject":[],"published":{"date-parts":[[2013]]}}}