{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T04:10:21Z","timestamp":1685419821294},"reference-count":0,"publisher":"National Library of Serbia","issue":"5","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Background\/Aim. Matrix metalloproteinase-9 (MMP-9) index is the ratio of\n   active MMP-9 and total MMP-9 levels. It reflects the importance of MMP-9 in\n   acute coronary syndrome (ACS). Methods. The study included 3 groups of\n   patients (n = 87): the group 1 - non-diabetic subjects without ACS\n   (control); the group 2 - diabetic patients with ACS [subgroups with unstable\n   angina pectoris (UAP), myocardial infarction (MI) or reinfarction]; and the\n   group 3 non-diabetics patients with ACS. Total and active MMP-9 were\n   measured and used to create MMP-9 index. Results. MMP-9 index, as a marker\n   showed good sensitivity and specificity, of ACS in diabetics, with a cut-off\n   value over 58.2. MMP-9 was higher in the study groups than in the control\n   one. MMP-9 correlated with ACS occurrence and type of cardiovascular event.\n   A statistically significant difference was found among the groups according\n   to active MMP-9 (p &lt; 0.001). The same was found with active MMP-9 between\n   the control and the group with MI (p &lt; 0.001). The control was highly\n   statistically significantly different from the group of patients with UAP (p\n   &lt; 0.01). Statically significant differences in MMP-9 index was found between\n   the control and the diabetics with ACS (p &lt; 0.001). Statistically\n   significant difference of MMP-9 index was also found in the controls\n   compared to the value in non-diabetic patients with ACS (p &lt; 0.01).\n   Conclusion. MMP-9 index may be a possible marker of atheromatous plaque\n   rupture in diabetics.<\/jats:p>","DOI":"10.2298\/vsp140204055p","type":"journal-article","created":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T06:23:02Z","timestamp":1409552582000},"page":"421-426","source":"Crossref","is-referenced-by-count":2,"title":["Matrix metalloproteinase-9 index as a possible parameter for predicting acute coronary syndrome in diabetics"],"prefix":"10.2298","volume":"72","author":[{"given":"Srdjan","family":"Popovic","sequence":"first","affiliation":[{"name":"Clinical Center of Serbia, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fadil","family":"Canovic","sequence":"additional","affiliation":[{"name":"Clinical Center of Serbia, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miroljub","family":"Ilic","sequence":"additional","affiliation":[{"name":"Clinical Center of Serbia, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saso","family":"Rafajlovski","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vesna","family":"Dimitrijevic-Sreckovic","sequence":"additional","affiliation":[{"name":"Clinical Center of Serbia, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragana","family":"Matanovic","sequence":"additional","affiliation":[{"name":"Clinical Center of Serbia, Clinic for Physical Medicine and Rehabilitation, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svetlana","family":"Vujovic","sequence":"additional","affiliation":[{"name":"Clinical Center of Serbia, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Belgrade, Serbia + Military Medical Academy, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Predrag","family":"Djordjevic","sequence":"additional","affiliation":[{"name":"University of Belgrade, Faculty of Medicine, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Drasko","family":"Gostiljac","sequence":"additional","affiliation":[{"name":"Clinical Center of Serbia, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:13:39Z","timestamp":1685358819000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84501400055P"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp140204055p","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"value":"0042-8450","type":"print"},{"value":"2406-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}