{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T15:40:39Z","timestamp":1770133239967,"version":"3.49.0"},"reference-count":0,"publisher":"National Library of Serbia","issue":"8","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Background\/Aim. Recurrent aphthous stomatitis (RAS) is defined as multifactor\n   immunologic inflammatory lesions in the oral cavity, characterized by\n   painful, recurrent single\/multiple, shallow, round or ovoid ulcerations of\n   mucosal tissues. To date, a considerable number of RAS treatment protocols\n   have been suggested, but since the etiology of RAS is idiopathic, these\n   treatment options have symptomatic rather than curative or preventive\n   effect. Recently, it has been suggested that laser therapy could be\n   successfully used as an efficient treatment approach in therapy of RAS.\n   Therefore, the aim of this review was to estimate the effects of laser\n   therapy in treatment of RAS analyzing results of clinical studies published\n   in peer reviewed journals. Methods. The studies published until 31 December\n   2013 were obtained from the Medline\/PubMed, Science Direct and Cochrane\n   Library of the Cochrane Collaboration (CENTRAL) online databases, using\n   following search terms and key words: ?laser? AND ?recurrent aphthous\n   stomatitis?, ?laser? AND ?aphthous?, and ?laser? AND ?aphthae?. In total 4\n   original research articles met the all required inclusion\/exclusion\n   criteria, and were used for this review. The main outcome measures assessed\n   were: a reduction of pain associated with RAS and a reduction in episode\n   duration (faster RAS healing). Results. The assessed literature demonstrates\n   the benefits of laser therapy mainly due to immediate analgesia and ability\n   to speed up a RAS healing process. Conclusion. Even though the assessed\n   literature suggests beneficial outcomes of laser therapy in treatment of\n   RAS, these results should be interpreted with caution. The issues related to\n   the study designs and different sets of laser irradiation parameters of a\n   limited number of available studies with the same treatment outcomes prevent\n   us from making definite conclusions.<\/jats:p>","DOI":"10.2298\/vsp140410028p","type":"journal-article","created":{"date-parts":[[2015,5,29]],"date-time":"2015-05-29T13:49:49Z","timestamp":1432907389000},"page":"722-728","source":"Crossref","is-referenced-by-count":13,"title":["Treatment of recurrent aphthous stomatitis by laser therapy: A systematic review of the literature"],"prefix":"10.2298","volume":"72","author":[{"given":"Verica","family":"Pavlic","sequence":"first","affiliation":[{"name":"Institute of Dentistry, Department of Periodontology and Oral Medicine, Banja Luka, Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vesna","family":"Vujic-Aleksic","sequence":"additional","affiliation":[{"name":"The Republic of Srpska Agency for Certification, Accreditation and Quality Improvement in Health Care, Banja Luka, Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Aoki","sequence":"additional","affiliation":[{"name":"Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Department of Hard Tissue Engineering, Section of Periodontology, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lana","family":"Nezic","sequence":"additional","affiliation":[{"name":"University of Banja Luka, Faculty of Medicine, Department of Pharmacology, Toxicology and Clinical Pharmacology, Banja Luka, Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:15:05Z","timestamp":1685358905000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84501500028P"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp140410028p","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"value":"0042-8450","type":"print"},{"value":"2406-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}