{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T04:10:35Z","timestamp":1685419835635},"reference-count":0,"publisher":"National Library of Serbia","issue":"7","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Bacground\/Aim. The therapy with intravesical instillation of bacillus\n   Calmette-Gu?rin (BCG) after transurethral resection (TUR) of tumor is the\n   gold standard of treatment of non-muscle invasive bladder cancer (NMIBC). The\n   role and importance of BCG intravesical therapy in various shape of tumors,\n   were confirmed by our previous investigation. The aim of this study was to\n   examine whether incidence of recurrence and tumor regression differs\n   depending on sex and age of patients. Methods. This study included a total of\n   899 patients suffering from NIMBC, treated at our institution from January 1,\n   2007 to March 1, 2013. Two groups of patients were formed: patients underwent\n   TUR + BCG therapy (the group I) and the group II with patients in whom TUR\n   was performed as only therapy. These two groups of patients were divided into\n   subgroups of respondents male and female, age 60 years or younger and older\n   than 60 years. Statistical analysis was performed using ?2 test and the\n   Kolmogorov-Smirnov test. Results. This research suggests that if the\n   frequency of recurrence is seen as the only parameter, considering all the\n   subjects, the lowest recurrence rate was determined in the male subjects,\n   aged 60 years and younger who had received BCG after TUR. A high statistical\n   significance was found in the incidence of recurrence in patients younger\n   than 60 years, depending on the response to the therapy, while in those older\n   than 60 years, the difference was at the level of statistical significance.\n   This can be attributed to a certain degree of infravesical obstruction in\n   older men. Conclusions. Sex and age of patients may have a significant\n   influence on the course and outcome of NMIBC. The disease has the most\n   malignant and most aggressive behavior when present in males older than 60\n   years.<\/jats:p>","DOI":"10.2298\/vsp140616003m","type":"journal-article","created":{"date-parts":[[2015,1,27]],"date-time":"2015-01-27T12:43:33Z","timestamp":1422362613000},"page":"596-601","source":"Crossref","is-referenced-by-count":1,"title":["The clinical course of non-muscle invasive bladder cancer after transuretral resection of the tumor with or without subsequent intravesical application of bacillus Calmette-Gu\u00e9rin: The influence of patients gender and age"],"prefix":"10.2298","volume":"72","author":[{"given":"Radovan","family":"Milosevic","sequence":"first","affiliation":[{"name":"Military Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Novak","family":"Milovic","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Predrag","family":"Aleksic","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miodrag","family":"Lazic","sequence":"additional","affiliation":[{"name":"Clinical Hospital Center \u201cDr Dragi\u0161a Mi\u0161ovi\u0107\u201d, Department of Urology, Faculty of Medicine, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Snezana","family":"Cerovic","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Institute for Pathology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rade","family":"Prelevic","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Clinic of Urology, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandar","family":"Spasic","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Clinic of Urology, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dejan","family":"Simic","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Clinic of Urology, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bozidar","family":"Kovacevic","sequence":"additional","affiliation":[{"name":"Military Medical Academy, Institute for Pathology, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:14:54Z","timestamp":1685358894000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84501500003M"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp140616003m","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"value":"0042-8450","type":"print"},{"value":"2406-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}