{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T12:33:53Z","timestamp":1752669233343,"version":"3.40.5"},"reference-count":0,"publisher":"National Library of Serbia","issue":"8","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VSP","VOJNOSANIT PREGL","VOJNOSANITETSKI PREG"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Background\/Aim. Pregnancies complicated with antiphospholipd syndrome are\n   associated with the increased perinatal mortality and morbidity. The aim of\n   this study was to assess perinatal outcome in pregnancies with primary\n   antiphospholipd syndrome. Methods. This prospective study evaluated perinatal\n   outcome in 25 pregnant women with antiphospholipid syndrome. After\n   establishing vital pregnancy all the patients were treated with\n   low-molecularweight heparin and aspirin. The perinatal outcome was measured\n   by rates of miscarriages, preterm deliveries, live births and neonatal\n   complications. Results. Of the 25 pregnancies, 20 (80%) resulted in live\n   birth, 3 (12%) in spontaneous abortion and 2 (8%) were stillbirths. The mean\n   gestational age at delivery was 37.2 ? 1.0 weeks, mean neonatal birth weight\n   was 2,930.4 ? 428.0 g. Prematurity occurs in 4 (20%) live births, and there\n   were 4 (20%) intrauterine growth restriction with mean birth weight 2,060 ?\n   210.6 g. Neonatal complications were present in 6 (30%) newborns. Adverse\n   perinatal outcome was significantly associated with anticardiolipin IgG\n   antibodies (p &lt; 0.01) and development of hypertension during pregnancy (p &lt;\n   0.01). Conclusion. Despite a high incidence of adverse perinatal outcomes in\n   pregnancies with primary antiphospholipid syndrome, early treatment with\n   aspirin and low-molecular-weight heparin, combined with meticulous\n   fetomaternal monitoring could be associated with a relatively high\n   probability of favorable perinatal outcome.<\/jats:p>","DOI":"10.2298\/vsp1408742c","type":"journal-article","created":{"date-parts":[[2014,7,31]],"date-time":"2014-07-31T09:26:38Z","timestamp":1406798798000},"page":"742-745","source":"Crossref","is-referenced-by-count":3,"title":["Prospective study of perinatal outcome in pregnancies with primary antiphospholipid syndrome"],"prefix":"10.2298","volume":"71","author":[{"given":"Aleksandar","family":"Cetkovic","sequence":"first","affiliation":[{"name":"Clinical Center of Serbia, Clinic of Gynecology and Obstetrics, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biljana","family":"Kastratovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0202-0673","authenticated-orcid":false,"given":"Ivana","family":"Novakovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Institute of Human Genetics, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1078","container-title":["Vojnosanitetski pregled","Military Medical and Pharmaceutical Journal of Serbia"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:14:37Z","timestamp":1685358877000},"score":1,"resource":{"primary":{"URL":"https:\/\/doiserbia.nb.rs\/Article.aspx?ID=0042-84501408742C"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.2298\/vsp1408742c","relation":{},"ISSN":["0042-8450","2406-0720"],"issn-type":[{"type":"print","value":"0042-8450"},{"type":"electronic","value":"2406-0720"}],"subject":[],"published":{"date-parts":[[2014]]}}}