{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:17:19Z","timestamp":1789870639551,"version":"4.0.1"},"reference-count":19,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2010,4,1]]},"abstract":"<jats:p>Our study aimed to examine the hypothesis that women have more stable plaques (a lower proportion of lipid component and a higher proportion of fibrous tissue) compared to men. Plaque specimens of 141 consecutive carotid endarterectomy patients (60 females and 81 males) were studied. Medical histories were recorded and the plasma concentrations of cholesterol and inflammatory markers were measured. We found that plaques from females had significantly less lipid than those from males ( p = .01): the mean percentage of plaque lipid for women and men was 47.8% and 58.2%, respectively. Plaques from females had more fibrous tissue than those from men ( p = .02): the mean percentage of fibrous tissue for women and men was 38.8% and 29.8%, respectively. This study concluded that the histology of carotid artery plaques from women appears to be more stable than that of those from men.<\/jats:p>","DOI":"10.2310\/6670.2010.00008","type":"journal-article","created":{"date-parts":[[2011,5,24]],"date-time":"2011-05-24T07:52:25Z","timestamp":1306223545000},"page":"77-81","source":"Crossref","is-referenced-by-count":8,"title":["Sex Difference in Composition of Plaques of Patients Undergoing Carotid Endarterectomy"],"prefix":"10.1177","volume":"18","author":[{"given":"Kittipan","family":"Rerkasem","sequence":"first","affiliation":[{"name":"*Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; \u2020Department of Pathology, Southampton General Hospital, Southampton, UK; \u2021Institute of Human Nutrition, University of Southampton, Southampton, UK; \u00a7Department of Vascular Surgery, Southampton General Hospital, Southampton, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Gallagher","sequence":"additional","affiliation":[{"name":"*Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; \u2020Department of Pathology, Southampton General Hospital, Southampton, UK; \u2021Institute of Human Nutrition, University of Southampton, Southampton, UK; \u00a7Department of Vascular Surgery, Southampton General Hospital, Southampton, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert F.","family":"Grimble","sequence":"additional","affiliation":[{"name":"*Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; \u2020Department of Pathology, Southampton General Hospital, Southampton, UK; \u2021Institute of Human Nutrition, University of Southampton, Southampton, UK; \u00a7Department of Vascular Surgery, Southampton General Hospital, Southampton, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip C.","family":"Calder","sequence":"additional","affiliation":[{"name":"*Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; \u2020Department of Pathology, Southampton General Hospital, Southampton, UK; \u2021Institute of Human Nutrition, University of Southampton, Southampton, UK; \u00a7Department of Vascular Surgery, Southampton General Hospital, Southampton, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clifford P.","family":"Shearman","sequence":"additional","affiliation":[{"name":"*Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; \u2020Department of Pathology, Southampton General Hospital, Southampton, UK; \u2021Institute of Human Nutrition, University of Southampton, Southampton, UK; \u00a7Department of Vascular Surgery, Southampton General Hospital, Southampton, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,6,23]]},"reference":[{"key":"bibr-bib1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurpsyc.1951.02320030083009"},{"key":"bibr-bib2","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1056\/NEJM199811123392002","volume":"339","author":"Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis","year":"1998","journal-title":"N Engl J Med"},{"key":"bibr-bib3","unstructured":"Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST)Lancet1998351137987"},{"key":"bibr-bib4","doi-asserted-by":"publisher","DOI":"10.1001\/jama.273.18.1421"},{"key":"bibr-bib5","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001923.pub2"},{"key":"bibr-bib6","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/S0140-6736(04)16146-1","volume":"363","author":"Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial","year":"2004","journal-title":"Lancet"},{"key":"bibr-bib7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15785-1"},{"key":"bibr-bib8","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000147040.20446.f6"},{"key":"bibr-bib9","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.108.177659"},{"key":"bibr-bib10","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S1078-5884(05)80194-7","volume":"10","author":"Carotid artery plaque composition-relationship to clinical presentation and ultrasound B-mode imaging","year":"1995","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"bibr-bib11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.09.051"},{"key":"bibr-bib12","doi-asserted-by":"publisher","DOI":"10.1159\/000207443"},{"key":"bibr-bib13","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.146.5.1061"},{"key":"bibr-bib14","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000166056.04922.f2"},{"key":"bibr-bib15","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000157141.00778.AC"},{"key":"bibr-bib16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2008.01.017"},{"key":"bibr-bib17","doi-asserted-by":"publisher","DOI":"10.1201\/b14239"},{"key":"bibr-bib18","doi-asserted-by":"publisher","DOI":"10.1159\/000086509"},{"key":"bibr-bib19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2000.tb04747.x"}],"container-title":["Vascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/6670.2010.00008","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/6670.2010.00008","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/6670.2010.00008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:30:56Z","timestamp":1777602656000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/6670.2010.00008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,1]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,4,1]]}},"alternative-id":["10.2310\/6670.2010.00008"],"URL":"https:\/\/doi.org\/10.2310\/6670.2010.00008","relation":{},"ISSN":["1708-5381","1708-539X"],"issn-type":[{"value":"1708-5381","type":"print"},{"value":"1708-539X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,1]]}}}